SAXSdb — 4yde

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1. Protein Identity and Related Structures Protein Identity & Related Structures

Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha

Candida albicans (strain SC5314 / ATCC MYA-2876)

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 2	Protein farnesyltransferase/geranylgeranyltransferase type-1 Subunit beta × 1 （Q59LE1） 1,2-ETHANEDIOL × 2 ZINC ION × 1 (3R,7S)-3,7,11-trimethyldodecyl trihydrogen diphosphate × 1 water × 2	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	Q5APE8_CANAL
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain A； PDBConstruct 25–329； UniProt 1–305

Protein farnesyltransferase/geranylgeranyltransferase type-1 Subunit beta

Candida albicans (strain SC5314 / ATCC MYA-2876)

UniProt Q59LE1

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 2	Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha × 1 （Q5APE8） 1,2-ETHANEDIOL × 2 ZINC ION × 1 (3R,7S)-3,7,11-trimethyldodecyl trihydrogen diphosphate × 1 water × 2	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	Q59LE1_CANAL
Isoform	—
PDB entities	2
Chains and sequence ranges	Author chain B； PDBConstruct 1–587； UniProt 1–587

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	4yde
Deposition date deposition_date	2015-02-22
Structure title title	CRYSTAL STRUCTURE OF CANDIDA ALBICANS PROTEIN FARNESYLTRANSFERASE BINARY COMPLEX WITH THE ISOPRENOID FARNESYLDIPHOSPHATE
Keywords keywords	Farnesyl transferase, TRANSFERASE; TRANSFERASE
Experimental Method method	X-RAY DIFFRACTION

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

4yde__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

4yde__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

4yde__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	27.27 Å
Rg (electron density)	26.14 Å
Total Rg	27.02 Å
Atom count	5910
Residues	714
Excluded volume	105380 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`4yde__assembly_1__model_1`	dimeric （2）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (6)

Entity 1 Entity 1 polymer

Description description	Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
Molecular weight formula_weight	39236.8 kDa
Source method src_method	man
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	A
Atom count atom_count	6060

MGSSHHHHHHSQDPNSSSARLQVDMTDSKYDYSDITPVDINTEEPQICQILYDEDYKQIMGILLSLMKAEEYSERALHITELGINELASHYTIWIYRFNILKNLPNRNLYDELDWCEEIALDNEKNYQIWNYRQLIIGQIMELNNNDFDPYREFPILEAMLSSDPKNHHVWSYRKWLVDTFDLHNDAKELSFVDKVIDTDLKNNSAWSHRFFLLFSKKHLATDNTIDEELNYVKDKIVKCPQNPSTWNYLLGIHERFDRSITQLEEFSLQFVDLEKDQVTSSFALETLAKIYTQQKKYNESRTVYDLLKSKYDPIRSNFWDYQISKLTS

Source Source

Source organism organism	Candida albicans (strain SC5314 / ATCC MYA-2876)
Common name common_name	Yeast
NCBI taxonomy ID ncbi_taxonomy_id	237561
Host organism host_organism	Escherichia coli

Entity 2 Entity 2 polymer

Description description	Protein farnesyltransferase/geranylgeranyltransferase type-1 Subunit beta
Molecular weight formula_weight	66693.3 kDa
Source method src_method	man
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	B

MSQDSNAKINYLLNIINSQRKPPIINNPSISSNTNRVRTKTKTRTRTSPNSKTKIKTKTMNTMKTNNRNSILTETEELFTNESQIIESFNSNCTIVDSNSDFHDKLHVYKSPIIDITKYFSPTVESQMDLELIILNEYYLKTHQHHQEQQNDEDEDEDEDDELNYFYIDAHLKYILSSLIDPMPSGYQVLDVNHSWMIYWLLNSYYLIQNPTMEINQSILDLIVNKITKCINYGDSLSGVPFDGIGGGNNQLGHLASTYAAILTLILTDQYELLDNLRELIRDWLLTLKKRSSCGSGASFIMHENGEMDARSTYCALIIINLLNLTNYEENSSSPEELDPLIDGVENWLNSCQTYEGGFSNIPNTEAHGGYTYCALASYFLLYDNRKQFSSGSTSSLSNSVCWEKLLEWSVHRQHELEGGVDGRTNKLVDACYGFWIGGLSPLLQLIIMNSSQGQGQQQEVKVFDEEKLRQYLLIIAQDESGGFKDKPGKQVDYYHTNYSLSGLSILEHSYKFSQDDEGRSLAFQIDVEREEEEEGGGGGGGGGGGDNFTNPIHPVFGIPIKFVKKCHDYFKLKPISKPKKRAEQKR

Source Source

Source organism organism	Candida albicans (strain SC5314 / ATCC MYA-2876)
Common name common_name	Yeast
NCBI taxonomy ID ncbi_taxonomy_id	237561
Host organism host_organism	Escherichia coli

Entity 3 Entity 3 non-polymer

Description description	1,2-ETHANEDIOL
Molecular weight formula_weight	62.1 kDa
Source method src_method	syn
Copy count entity_count	2

Entity 4 Entity 4 non-polymer

Description description	ZINC ION
Molecular weight formula_weight	65.4 kDa
Source method src_method	syn
Copy count entity_count	1

Entity 5 Entity 5 non-polymer

Description description	(3R,7S)-3,7,11-trimethyldodecyl trihydrogen diphosphate
Molecular weight formula_weight	388.4 kDa
Source method src_method	syn
Copy count entity_count	1

Entity 6 Entity 6 water

Description description	water
Molecular weight formula_weight	18.0 kDa
Source method src_method	nat
Copy count entity_count	150

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6. Fold Classification (SCOP + CATH) 3 domains

SCOP 2.08 (1 domains)

Domain ID domain_id	d4ydea_
Class class	a — All alpha proteins
Fold Fold fold	a.118 — alpha-alpha superhelix
Superfamily Superfamily superfamily	a.118.6 — Protein prenylyltransferase
Family Family family	a.118.6.0 — automated matches

CATH v4.4 (2 domains)

Domain ID domain_id	4ydeA00
Class class	1 — Mainly Alpha
Architecture architecture	25 — Alpha Horseshoe
Topology topology	40 — Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat
Homologous superfamily homologous superfamily	120 — Protein prenylyltransferase

Domain ID domain_id	4ydeB00
Class class	1 — Mainly Alpha
Architecture architecture	50 — Alpha/alpha barrel
Topology topology	10 — Glycosyltransferase
Homologous superfamily homologous superfamily	20 —

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Unit-cell length a length_a	98.874 Å
Unit-cell length b length_b	98.874 Å
Unit-cell length c length_c	188.616 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	8

Space group space_group	P 43 2 2
Space-group number int_tables_number	95
Crystal system crystal_system	—

Resolution resolution	2.701 Å
Low-resolution limit resolution_low	47.822 Å
R factor r_factor	0.1972
R_work r_work	0.1946
R_free r_free	0.2281

CRYSTAL STRUCTURE OF CANDIDA ALBICANS PROTEIN FARNESYLTRANSFERASE BINARY COMPLEX WITH THE ISOPRENOID FARNESYLDIPHOSPHATE

1. Protein Identity and Related Structures Protein Identity & Related Structures

Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha

State in the Current Structure

Other States of the Same Protein in the Database

Protein farnesyltransferase/geranylgeranyltransferase type-1 Subunit beta

State in the Current Structure

Other States of the Same Protein in the Database

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

4yde__assembly_1__model_1

4yde__assembly_1__model_1 | I(q)

4yde__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (6)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 polymer

Polymer Polymer

Source Source

Entity 3 Entity 3 non-polymer

Entity 4 Entity 4 non-polymer

Entity 5 Entity 5 non-polymer

Entity 6 Entity 6 water

6. Fold Classification (SCOP + CATH) 3 domains

SCOP 2.08 (1 domains)

CATH v4.4 (2 domains)

7. Citations (1)

CRYSTAL STRUCTURE OF CANDIDA ALBICANS PROTEIN FARNESYLTRANSFERASE BINARY COMPLEX WITH THE ISOPRENOID FARNESYLDIPHOSPHATE

1. Protein Identity and Related Structures Protein Identity & Related Structures

Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Protein farnesyltransferase/geranylgeranyltransferase type-1 Subunit beta

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

4yde__assembly_1__model_1

4yde__assembly_1__model_1 | I(q)

4yde__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (6)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 polymer

Polymer Polymer

Source Source

Entity 3 Entity 3 non-polymer

Entity 4 Entity 4 non-polymer

Entity 5 Entity 5 non-polymer

Entity 6 Entity 6 water

6. Fold Classification (SCOP + CATH) 3 domains

SCOP 2.08 (1 domains)

CATH v4.4 (2 domains)

7. Citations (1)