Homo sapiens
| Assembly | 物理组成 | 蛋白状态 | 分子拷贝数 | 共同组分 | 数据核对 |
|---|---|---|---|---|---|
| 1 | 蛋白同源多聚体 | 同源多聚体 | 蛋白 2 | MAGNESIUM ION × 2 PHOSPHATE ION × 2 1-{2-deoxy-3,5-O-[phenyl(phosphono)methylidene]-beta-D-threo-pentofuranosyl}-5-[(E)-2-phosphonoethenyl]pyrimidine-2,4(1H,3H)-dione × 2 GLYCEROL × 1 water × 2 | 与蛋白数一致 |
| UniProt名称 | NT5C_HUMAN |
| Isoform | — |
| PDB实体 | 1 |
| 链与序列区间 | 作者链 A； PDB构建体 1–195； UniProt 1–195 作者链 B； PDB构建体 1–195； UniProt 1–195 |
页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。
| 条目编号 entry_id | 4yih |
| 沉积日期 deposition_date | 2015-03-02 |
| 结构标题 title | Crystal structure of human cytosolic 5'(3')-deoxyribonucleotidase in complex with the inhibitor PB-PVU |
| 关键词 keywords | ;5'-nucleotidase, dephosphorylation, phosphorylation, HAD-like, mitochondria, HYDROLASE-HYDROLASE INHIBITOR complex ;; HYDROLASE/HYDROLASE INHIBITOR |
| 实验方法 method | X-RAY DIFFRACTION |
页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 23.31 Å |
| Rg（电子密度） | 22.30 Å |
| 总 Rg | 23.08 Å |
| 原子数 | 3140 |
| 残基数 | 379 |
| 排除体积 | 55602 ų |
| 最大 q | 0.500 Å⁻¹ |
| 结构域编号 domain_id | d4yiha_ |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.108 — HAD-like |
| 超家族 Superfamily superfamily | c.108.1 — HAD-like |
| 家族 Family family | c.108.1.8 — 5'(3')-deoxyribonucleotidase (dNT-2) |
| 结构域编号 domain_id | d4yihb_ |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.108 — HAD-like |
| 超家族 Superfamily superfamily | c.108.1 — HAD-like |
| 家族 Family family | c.108.1.8 — 5'(3')-deoxyribonucleotidase (dNT-2) |
| 结构域编号 domain_id | 4yihA01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 1000 — HAD superfamily/HAD-like |
| 结构域编号 domain_id | 4yihA02 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 40 — Ribonucleotide Reductase Protein R1; domain 1 |
| 同源超家族 H-superfamily homologous superfamily | 40 — Deoxyribonucleotidase; domain 2 |
| 结构域编号 domain_id | 4yihB01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 1000 — HAD superfamily/HAD-like |
| 结构域编号 domain_id | 4yihB02 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 40 — Ribonucleotide Reductase Protein R1; domain 1 |
| 同源超家族 H-superfamily homologous superfamily | 40 — Deoxyribonucleotidase; domain 2 |