SAXSdb — 5anr

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1. Protein Identity and Related Structures Protein Identity & Related Structures

CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1

HOMO SAPIENS

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 3	PROBABLE ATP-DEPENDENT RNA HELICASE DDX6 × 1 （P26196） EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TRANSPORTER × 1 （Q9NRA8） water × 3	Consistent with protein count
2	Protein heterocomplex	Heteromer	Protein 3	PROBABLE ATP-DEPENDENT RNA HELICASE DDX6 × 1 （P26196） EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TRANSPORTER × 1 （Q9NRA8） water × 3	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	CNOT1_HUMAN
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain A； PDBConstruct 7–258； UniProt 1063–1314

PROBABLE ATP-DEPENDENT RNA HELICASE DDX6

HOMO SAPIENS

UniProt P26196

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 3	CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1 × 1 （A5YKK6） EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TRANSPORTER × 1 （Q9NRA8） water × 3	Consistent with protein count
2	Protein heterocomplex	Heteromer	Protein 3	CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1 × 1 （A5YKK6） EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TRANSPORTER × 1 （Q9NRA8） water × 3	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	DDX6_HUMAN
Isoform	—
PDB entities	2
Chains and sequence ranges	Author chain B； PDBConstruct 4–378； UniProt 95–469

EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TRANSPORTER

HOMO SAPIENS

UniProt Q9NRA8

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein heterocomplex	Heteromer	Protein 3	CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1 × 1 （A5YKK6） PROBABLE ATP-DEPENDENT RNA HELICASE DDX6 × 1 （P26196） water × 3	Consistent with protein count
2	Protein heterocomplex	Heteromer	Protein 3	CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1 × 1 （A5YKK6） PROBABLE ATP-DEPENDENT RNA HELICASE DDX6 × 1 （P26196） water × 3	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	4ET_HUMAN
Isoform	—
PDB entities	3
Chains and sequence ranges	Author chain C； PDBConstruct 4–44； UniProt 199–239

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	5anr
Deposition date deposition_date	2015-09-08
Structure title title	Structure of a human 4E-T - DDX6 - CNOT1 complex
Keywords keywords	RNA BINDING PROTEIN; RNA BINDING PROTEIN
Experimental Method method	X-RAY DIFFRACTION

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

5anr__assembly_2__model_1

Assembly 2 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

5anr__assembly_2__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

5anr__assembly_2__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	28.33 Å
Rg (electron density)	27.06 Å
Total Rg	27.88 Å
Atom count	4929
Residues	628
Excluded volume	88685 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`5anr__assembly_1__model_1`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download
2	1	`5anr__assembly_2__model_1`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (4)

Entity 1 Entity 1 polymer

Description description	CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1
Molecular weight formula_weight	29695.4 kDa
Source method src_method	man
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	A
Atom count atom_count	5205

QGPDSMKKDVPPSINTTNIDTLLVATDQTERIVEPPENIQEKIAFIFNNLSQSNMTQKVEELKETVKEEFMPWVSQYLVMKRVSIEPNFHSLYSNFLDTLKNPEFNKMVLNETYRNIKVLLTSDKAAANFSDRSLLKNLGHWLGMITLAKNKPILHTDLDVKSLLLEAYVKGQQELLYVVPFVAKVLESSIRSVVFRPPNPWTMAIMNVLAELHQEHDLKLNLKFEIEVLCKNLALDINELKPGNLLKDKDRLKNLDE

Source Source

Source organism organism	HOMO SAPIENS
Common name common_name	HUMAN
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	ESCHERICHIA COLI

Entity 2 Entity 2 polymer

Description description	PROBABLE ATP-DEPENDENT RNA HELICASE DDX6
Molecular weight formula_weight	43189.2 kDa
EC 编号 ec_number	3.6.4.13
Source method src_method	man
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	B

RSMGNEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINLMEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLY

Source Source

Source organism organism	HOMO SAPIENS
Common name common_name	HUMAN
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	ESCHERICHIA COLI

Entity 3 Entity 3 polymer

Description description	EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TRANSPORTER
Molecular weight formula_weight	5092.4 kDa
Source method src_method	man
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	C

RSMGDSKRVFGERRRNDSYTEEEPEWFSAGPTSQSETIELTGFD

Source Source

Source organism organism	HOMO SAPIENS
Common name common_name	HUMAN
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	ESCHERICHIA COLI

Entity 4 Entity 4 water

Description description	water
Molecular weight formula_weight	18.0 kDa
Source method src_method	nat
Copy count entity_count	276

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6. Fold Classification (SCOP + CATH) 5 domains

SCOP 2.08 (2 domains)

Domain ID domain_id	d5anrb1
Class class	c — Alpha and beta proteins (a/b)
Fold Fold fold	c.37 — P-loop containing nucleoside triphosphate hydrolases
Superfamily Superfamily superfamily	c.37.1 — P-loop containing nucleoside triphosphate hydrolases
Family Family family	c.37.1.0 — automated matches

Domain ID domain_id	d5anrb2
Class class	c — Alpha and beta proteins (a/b)
Fold Fold fold	c.37 — P-loop containing nucleoside triphosphate hydrolases
Superfamily Superfamily superfamily	c.37.1 — P-loop containing nucleoside triphosphate hydrolases
Family Family family	c.37.1.0 — automated matches

CATH v4.4 (3 domains)

Domain ID domain_id	5anrA00
Class class	1 — Mainly Alpha
Architecture architecture	25 — Alpha Horseshoe
Topology topology	40 — Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat
Homologous superfamily homologous superfamily	180 —

Domain ID domain_id	5anrB01
Class class	3 — Alpha Beta
Architecture architecture	40 — 3-Layer(aba) Sandwich
Topology topology	50 — Rossmann fold
Homologous superfamily homologous superfamily	300 — P-loop containing nucleotide triphosphate hydrolases

Domain ID domain_id	5anrB02
Class class	3 — Alpha Beta
Architecture architecture	40 — 3-Layer(aba) Sandwich
Topology topology	50 — Rossmann fold
Homologous superfamily homologous superfamily	300 — P-loop containing nucleotide triphosphate hydrolases

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Unit-cell length a length_a	93.129 Å
Unit-cell length b length_b	93.129 Å
Unit-cell length c length_c	175.329 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	120.00 °
Molecules per unit cell Z z_pdb	6

Space group space_group	P 32 2 1
Space-group number int_tables_number	154
Crystal system crystal_system	—

Resolution resolution	2.102 Å
Low-resolution limit resolution_low	47.324 Å
R factor r_factor	0.1950
R_work r_work	0.1931
R_free r_free	0.2319

Structure of a human 4E-T - DDX6 - CNOT1 complex

1. Protein Identity and Related Structures Protein Identity & Related Structures

CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1

State in the Current Structure

Other States of the Same Protein in the Database

PROBABLE ATP-DEPENDENT RNA HELICASE DDX6

State in the Current Structure

Other States of the Same Protein in the Database

EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TRANSPORTER

State in the Current Structure

Other States of the Same Protein in the Database

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

5anr__assembly_2__model_1

5anr__assembly_2__model_1 | I(q)

5anr__assembly_2__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (4)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 polymer

Polymer Polymer

Source Source

Entity 3 Entity 3 polymer

Polymer Polymer

Source Source

Entity 4 Entity 4 water

6. Fold Classification (SCOP + CATH) 5 domains

SCOP 2.08 (2 domains)

CATH v4.4 (3 domains)

7. Citations (1)

Structure of a human 4E-T - DDX6 - CNOT1 complex

1. Protein Identity and Related Structures Protein Identity & Related Structures

CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

PROBABLE ATP-DEPENDENT RNA HELICASE DDX6

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TRANSPORTER

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

5anr__assembly_2__model_1

5anr__assembly_2__model_1 | I(q)

5anr__assembly_2__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (4)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 polymer

Polymer Polymer

Source Source

Entity 3 Entity 3 polymer

Polymer Polymer

Source Source

Entity 4 Entity 4 water

6. Fold Classification (SCOP + CATH) 5 domains

SCOP 2.08 (2 domains)

CATH v4.4 (3 domains)

7. Citations (1)