← Back to search
5aw6

Kinetics by X-ray crystallography: Rb+-substitution of bound K+ in the E2.MgF42-.2K+ crystal after 5.5 min

Method: X-RAY DIFFRACTION
▼

1. Protein Identity and Related Structures Protein Identity & Related Structures

Na, K-ATPase alpha subunit

OrganismNot specified

UniProt Q4H132

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 3 其他Polymer 1 Na+,K+-ATPase beta subunit × 1 （C4IX13） Phospholemman-like protein × 1 （Q70Q12） 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 1 TETRAFLUOROMAGNESATE(2-) × 1 MAGNESIUM ION × 1 POTASSIUM ION × 3 RUBIDIUM ION × 3 CHOLESTEROL × 1 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 water × 1 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
2zxe 3a3y 5avq 5avr 5avs 5avt 5avu 5avv 5avw 5avx 5avy 5avz

44 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name Q4H132_SQUAC
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–1028； UniProt 1–1028

Na+,K+-ATPase beta subunit

OrganismNot specified

UniProt C4IX13

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 3 其他Polymer 1 Na, K-ATPase alpha subunit × 1 （Q4H132） Phospholemman-like protein × 1 （Q70Q12） 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 1 TETRAFLUOROMAGNESATE(2-) × 1 MAGNESIUM ION × 1 POTASSIUM ION × 3 RUBIDIUM ION × 3 CHOLESTEROL × 1 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 water × 1 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
5avq 5avr 5avs 5avt 5avu 5avv 5avw 5avx 5avy 5avz 5aw0 5aw1

42 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name C4IX13_SQUAC
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B； PDBConstruct 1–305； UniProt 1–305

Phospholemman-like protein

OrganismNot specified

UniProt Q70Q12

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Heteromer Protein 3 其他Polymer 1 Na, K-ATPase alpha subunit × 1 （Q4H132） Na+,K+-ATPase beta subunit × 1 （C4IX13） 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 1 TETRAFLUOROMAGNESATE(2-) × 1 MAGNESIUM ION × 1 POTASSIUM ION × 3 RUBIDIUM ION × 3 CHOLESTEROL × 1 2-acetamido-2-deoxy-beta-D-glucopyranose × 1 water × 1 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
2zxe 3a3y 5avq 5avr 5avs 5avt 5avu 5avv 5avw 5avx 5avy 5avz

44 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name Q70Q12_SQUAC
Isoform —
PDB entities 3
Chains and sequence ranges Author chain G； PDBConstruct 1–74； UniProt 21–94

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

▼

2. Structure Basics 2. Structure Basics

Entry ID entry_id5aw6
Deposition date deposition_date2015-07-01
Structure title titleKinetics by X-ray crystallography: Rb+-substitution of bound K+ in the E2.MgF42-.2K+ crystal after 5.5 min
Keywords keywords;MEMBRANE PROTEIN, ION PUMP, ATPASE, K+ BINDING, HALOACID DEHYDROGENEASE SUPERFAMILY, PHOSPHATE ANALOGUE, ATP-BINDING, HYDROLASE, ION TRANSPORT, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, HYDROLASE-TRANSPORT PROTEIN COMPLEX, KINETICS ;; HYDROLASE/TRANSPORT PROTEIN
Experimental Method methodX-RAY DIFFRACTION
▼

3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

5aw6__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

5aw6__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

5aw6__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）46.90 Å
Rg (electron density)47.04 Å
Total Rg46.80 Å
Atom count10233
Residues1299
Excluded volume183920 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 5aw6__assembly_1__model_1 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
▶

4. Crystallography and Experiment 4. Crystallography & Experiment

▶

5. Entities and Polymers Entities & Polymers (11)

▼

6. Fold Classification (SCOP + CATH) 13 domains

SCOP 2.08 (7 domains)

Domain ID domain_idd5aw6a1
Class classf — Membrane and cell surface proteins and peptides
Fold Fold foldf.33 — Metal cation-transporting ATPase, transmembrane domain
Superfamily Superfamily superfamilyf.33.1 — Metal cation-transporting ATPase, transmembrane domain
Family Family familyf.33.1.1 — Metal cation-transporting ATPase, transmembrane domain
Domain ID domain_idd5aw6a2
Class classb — All beta proteins
Fold Fold foldb.82 — Double-stranded beta-helix
Superfamily Superfamily superfamilyb.82.7 — Metal cation-transporting ATPase, actuator domain A
Family Family familyb.82.7.1 — Metal cation-transporting ATPase, actuator domain A
Domain ID domain_idd5aw6a3
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.108 — HAD-like
Superfamily Superfamily superfamilyc.108.1 — HAD-like
Family Family familyc.108.1.7 — Meta-cation ATPase, catalytic domain P
Domain ID domain_idd5aw6a4
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.220 — Metal cation-transporting ATPase, ATP-binding domain N
Superfamily Superfamily superfamilyd.220.1 — Metal cation-transporting ATPase, ATP-binding domain N
Family Family familyd.220.1.1 — Metal cation-transporting ATPase, ATP-binding domain N
Domain ID domain_idd5aw6b1
Class classf — Membrane and cell surface proteins and peptides
Fold Fold foldf.23 — Single transmembrane helix
Superfamily Superfamily superfamilyf.23.42 — Sodium/potassium-transporting ATPase, beta subunit transmembrane helix
Family Family familyf.23.42.1 — Sodium/potassium-transporting ATPase, beta subunit transmembrane helix
Domain ID domain_idd5aw6b2
Class classb — All beta proteins
Fold Fold foldb.1 — Immunoglobulin-like beta-sandwich
Superfamily Superfamily superfamilyb.1.32 — Sodium/potassium-transporting ATPase, beta subunit extracellular domain
Family Family familyb.1.32.1 — Sodium/potassium-transporting ATPase, beta subunit extracellular domain
Domain ID domain_idd5aw6g_
Class classf — Membrane and cell surface proteins and peptides
Fold Fold foldf.23 — Single transmembrane helix
Superfamily Superfamily superfamilyf.23.43 — ATP1G1/PLM/MAT8-like (FXYD-like)
Family Family familyf.23.43.1 — ATP1G1/PLM/MAT8-like (FXYD-like)

CATH v4.4 (6 domains)

Domain ID domain_id5aw6A01
Class class2 — Mainly Beta
Architecture architecture70 — Distorted Sandwich
Topology topology150 — Calcium-transporting ATPase, cytoplasmic transduction domain A
Homologous superfamily homologous superfamily10 — Calcium-transporting ATPase, cytoplasmic transduction domain A
Domain ID domain_id5aw6A02
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology1110 — Calcium-transporting ATPase, transmembrane domain
Homologous superfamily homologous superfamily10 — Calcium-transporting ATPase, transmembrane domain
Domain ID domain_id5aw6A03
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily1000 — HAD superfamily/HAD-like
Domain ID domain_id5aw6A04
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology1110 — Calcium-transporting ATPase, cytoplasmic domain N
Homologous superfamily homologous superfamily10 — Calcium-transporting ATPase, cytoplasmic domain N
Domain ID domain_id5aw6B01
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily170 —
Domain ID domain_id5aw6B02
Class class2 — Mainly Beta
Architecture architecture60 — Sandwich
Topology topology40 — Immunoglobulin-like
Homologous superfamily homologous superfamily1660 — Na, k-atpase alpha subunit.
▶

7. Citations (1)