Homo sapiens
| Assembly | 物理组成 | 蛋白状态 | 分子拷贝数 | 共同组分 | 数据核对 |
|---|---|---|---|---|---|
| 1 | 蛋白异源复合物 | 异源复合物 | 蛋白 2 | nanobody MU1053 × 1 water × 2 | 与蛋白数一致 |
| 2 | 蛋白异源复合物 | 异源复合物 | 蛋白 2 | nanobody MU1053 × 1 water × 2 | 与蛋白数一致 |
| UniProt名称 | CD38_HUMAN |
| Isoform | — |
| PDB实体 | 1 |
| 链与序列区间 | 作者链 A； PDB构建体 1–256； UniProt 45–300 作者链 B； PDB构建体 1–256； UniProt 45–300 |
页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。
| 条目编号 entry_id | 5f1k |
| 沉积日期 deposition_date | 2015-11-30 |
| 结构标题 title | human CD38 in complex with nanobody MU1053 |
| 关键词 keywords | ;CD38, ADP-ribosyl cyclase, cyclic ADP-ribose, X-crystallography, Calcium signaling, nanobody, MU1053, HYDROLASE-IMMUNE SYSTEM complex ;; HYDROLASE/IMMUNE SYSTEM |
| 实验方法 method | X-RAY DIFFRACTION |
页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 24.47 Å |
| Rg（电子密度） | 23.64 Å |
| 总 Rg | 24.43 Å |
| 原子数 | 2899 |
| 残基数 | 367 |
| 排除体积 | 51221 ų |
| 最大 q | 0.500 Å⁻¹ |
| 结构域编号 domain_id | d5f1ka_ |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.23 — Flavodoxin-like |
| 超家族 Superfamily superfamily | c.23.14 — N-(deoxy)ribosyltransferase-like |
| 家族 Family family | c.23.14.3 — ADP ribosyl cyclase-like |
| 结构域编号 domain_id | d5f1kb_ |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.23 — Flavodoxin-like |
| 超家族 Superfamily superfamily | c.23.14 — N-(deoxy)ribosyltransferase-like |
| 家族 Family family | c.23.14.3 — ADP ribosyl cyclase-like |
| 结构域编号 domain_id | d5f1kc_ |
| 类 Class class | b — All beta proteins |
| 折叠类型 Fold fold | b.1 — Immunoglobulin-like beta-sandwich |
| 超家族 Superfamily superfamily | b.1.1 — Immunoglobulin |
| 家族 Family family | b.1.1.0 — automated matches |
| 结构域编号 domain_id | d5f1kd_ |
| 类 Class class | b — All beta proteins |
| 折叠类型 Fold fold | b.1 — Immunoglobulin-like beta-sandwich |
| 超家族 Superfamily superfamily | b.1.1 — Immunoglobulin |
| 家族 Family family | b.1.1.0 — automated matches |
| 结构域编号 domain_id | 5f1kA01 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 20 — Up-down Bundle |
| 拓扑 Topology topology | 82 — ADP Ribosyl Cyclase; Chain A, domain 1 |
| 同源超家族 H-superfamily homologous superfamily | 10 — ADP Ribosyl Cyclase; Chain A, domain 1 |
| 结构域编号 domain_id | 5f1kA02 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 720 — NAD(P)-binding Rossmann-like Domain |
| 结构域编号 domain_id | 5f1kB01 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 20 — Up-down Bundle |
| 拓扑 Topology topology | 82 — ADP Ribosyl Cyclase; Chain A, domain 1 |
| 同源超家族 H-superfamily homologous superfamily | 10 — ADP Ribosyl Cyclase; Chain A, domain 1 |
| 结构域编号 domain_id | 5f1kB02 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 720 — NAD(P)-binding Rossmann-like Domain |
| 结构域编号 domain_id | 5f1kC00 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 60 — Sandwich |
| 拓扑 Topology topology | 40 — Immunoglobulin-like |
| 同源超家族 H-superfamily homologous superfamily | 10 — Immunoglobulins |
| 结构域编号 domain_id | 5f1kD00 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 60 — Sandwich |
| 拓扑 Topology topology | 40 — Immunoglobulin-like |
| 同源超家族 H-superfamily homologous superfamily | 10 — Immunoglobulins |