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5fhc

Crystal Structure of Protective Human Antibodies 100 and 114 in Complex with Ebola Virus Fusion Glycoprotein (GP)

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Envelope glycoprotein

Zaire ebolavirus (strain Mayinga-76)

UniProt Q05320

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 6 Antibody 100 Fab heavy chain × 1 Antibody 100 Fab light chain × 1 Antibody 114 Fab light chain × 1 Antibody 114 Fab heavy chain × 1 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
2rlj

1 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers
2ebo

1 assemblies

Heteromeric or nucleic-acid complex
3csy 3csy 5fhc 5hj3 5hj3 5jq3 5jq7 5jqb 5kel 5kem 5ken 6eay

41 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name VGP_EBOZM
Isoform —
PDB entities 1, 2
Chains and sequence ranges Author chain J； PDBConstruct 1–98； UniProt 502–599 Author chain K； PDBConstruct 1–308； UniProt 1–308 Author chain K； PDBConstruct 311–322； UniProt 490–501

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id5fhc
Deposition date deposition_date2015-12-21
Structure title titleCrystal Structure of Protective Human Antibodies 100 and 114 in Complex with Ebola Virus Fusion Glycoprotein (GP)
Keywords keywordsIg domain, Fab, immune system, fusion, ebola virus, glycoprotein, GP, VIRAL PROTEIN-IMMUNE SYSTEM complex; VIRAL PROTEIN/IMMUNE SYSTEM
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

5fhc__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

5fhc__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

5fhc__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）46.90 Å
Rg (electron density)47.47 Å
Total Rg47.69 Å
Atom count8854
Residues1182
Excluded volume156710 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 5fhc__assembly_1__model_1 hexameric （6） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (6)

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7. Citations (1)