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5igm

Crystal structure of the bromodomain of human BRD9 in complex with bromosporine (BSP)

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Bromodomain-containing protein 9

Homo sapiens

UniProt Q9H8M2

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 2 Bromosporine × 2 water × 2 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
4uiv 4xy8 4yy4 4z6h 4z6h 4z6i 4z6i 5eu1 5eu1 5f1h 5f1h 5f1l

50 assemblies; showing the first 12

Homodimer
3hme 5e9v 5igm 5ign 6v0s 6v1b 9kla 9km1 9lkr

9 assemblies

Homotetramer
5twx

1 assemblies

Other homooligomers

None

Heteromeric or nucleic-acid complex
21ge 21hj 4yy6 4yyd 4yyg 4yyh 4yyh 4yyi 4yyi 4yyj 4yyj 4yyk

14 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name BRD9_HUMAN
Isoform Q9H8M2-1
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 3–123； UniProt 14–134 Author chain B； PDBConstruct 3–123； UniProt 14–134

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id5igm
Deposition date deposition_date2016-02-28
Structure title titleCrystal structure of the bromodomain of human BRD9 in complex with bromosporine (BSP)
Keywords keywordschromatin remodeling, transcription, Structural Genomics, Structural Genomics Consortium, SGC; TRANSCRIPTION
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

5igm__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

5igm__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

5igm__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）23.32 Å
Rg (electron density)23.09 Å
Total Rg23.67 Å
Atom count1877
Residues225
Excluded volume33920 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 5igm__assembly_1__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

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6. Fold Classification (SCOP + CATH) 4 domains

SCOP 2.08 (2 domains)

Domain ID domain_idd5igma_
Class classa — All alpha proteins
Fold Fold folda.29 — Bromodomain-like
Superfamily Superfamily superfamilya.29.2 — Bromodomain
Family Family familya.29.2.0 — automated matches
Domain ID domain_idd5igmb_
Class classa — All alpha proteins
Fold Fold folda.29 — Bromodomain-like
Superfamily Superfamily superfamilya.29.2 — Bromodomain
Family Family familya.29.2.0 — automated matches

CATH v4.4 (2 domains)

Domain ID domain_id5igmA00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology920 — Histone Acetyltransferase; Chain A
Homologous superfamily homologous superfamily10 — Bromodomain-like
Domain ID domain_id5igmB00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology920 — Histone Acetyltransferase; Chain A
Homologous superfamily homologous superfamily10 — Bromodomain-like
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7. Citations (1)