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5ko0

Human Islet Amyloid Polypeptide Segment 15-FLVHSSNNFGA-25 Determined by MicroED

Method: ELECTRON CRYSTALLOGRAPHY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

hIAPP(15-25)WT

OrganismNot specified

UniProt P10997

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 18 THIOCYANATE ION × 9 water × 18 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1kuw 2kb8 2l86 3fr1 5mgq 6ucj 6uck

7 assemblies

Homodimer
3fr1 3fr1

2 assemblies

Homotetramer

None

Other homooligomers
5knz 5ko0 6y1a 6zrf 6zrq 6zrr 7m61 7m62 7m64 7m65 7ykw 7yl0

39 assemblies; showing the first 12

Heteromeric or nucleic-acid complex
2g48 2g48 3g7v 3g7v 3g7w 3g7w 3hgz 3hgz 5k5g 6vw2 7bg0 7bg0

14 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name IAPP_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–11； UniProt 48–58 Author chain B； PDBConstruct 1–11； UniProt 48–58

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id5ko0
Deposition date deposition_date2016-06-28
Structure title titleHuman Islet Amyloid Polypeptide Segment 15-FLVHSSNNFGA-25 Determined by MicroED
Keywords keywordsAmyloid, islet amyloid polypeptide, Type II Diabetes, Toxic Spine, MicroED, PROTEIN FIBRIL; PROTEIN FIBRIL
Experimental Method methodELECTRON CRYSTALLOGRAPHY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

5ko0__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

5ko0__assembly_1__model_1 | I(q)

10-2 10-1 105 106 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

5ko0__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）30.59 Å
Rg (electron density)32.27 Å
Total Rg31.98 Å
Atom count1557
Residues198
Excluded volume26813 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 5ko0__assembly_1__model_1 octadecameric （18） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

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7. Citations (1)