5vxl

2.80 A resolution structure of IpaD from Shigella flexneri in complex with single-domain antibody JPS-G3

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Invasin IpaD

Shigella flexneri

UniProt P18013

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 2 single-domain antibody JPS-G3 × 1 water × 2 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name IPAD_SHIFL
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 6–289; UniProt 39–322

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id5vxl
Deposition date deposition_date2017-05-23
Structure title title2.80 A resolution structure of IpaD from Shigella flexneri in complex with single-domain antibody JPS-G3
Keywords keywordstip protein, VHH, T3SS, IMMUNE SYSTEM; IMMUNE SYSTEM
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

5vxl__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

5vxl__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

5vxl__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)26.70 Å
Rg (electron density)26.17 Å
Total Rg26.78 Å
Atom count5890
Residues391
Excluded volume52801 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 5vxl__assembly_1__model_1 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

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6. Fold Classification (SCOP + CATH) 3 domains

SCOP 2.08 (2 domains)

Domain ID domain_idd5vxla_
Class classa — All alpha proteins
Fold Fold folda.250 — IpaD-like
Superfamily Superfamily superfamilya.250.1 — IpaD-like
Family Family familya.250.1.1 — IpaD-like
Domain ID domain_idd5vxlb_
Class classb — All beta proteins
Fold Fold foldb.1 — Immunoglobulin-like beta-sandwich
Superfamily Superfamily superfamilyb.1.1 — Immunoglobulin
Family Family familyb.1.1.0 — automated matches

CATH v4.4 (1 domains)

Domain ID domain_id5vxlA00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology1710 — IpaD-like
Homologous superfamily homologous superfamily10 — IpaD-like
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7. Citations (1)