Homo sapiens
| Assembly | Physical composition | Protein state | Molecular copy count | Associated components | Data consistency |
|---|---|---|---|---|---|
| 1 | Protein monomer | Monomer | Protein 1 | 5-nitroquinolin-8-ol × 1 water × 1 | Consistent with protein count |
| UniProt name | BRD4_HUMAN |
| Isoform | — |
| PDB entities | 1 |
| Chains and sequence ranges | Author chain A； PDBConstruct 2–125； UniProt 44–167 |
The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.
| Entry ID entry_id | 5y1y |
| Deposition date deposition_date | 2017-07-21 |
| Structure title title | Complex structure of nitroxoline with the first bromodomain of BRD4 |
| Keywords keywords | BRD4 inhibitor Approved drugs, TRANSCRIPTION; TRANSCRIPTION |
| Experimental Method method | X-RAY DIFFRACTION |
This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 15.80 Å |
| Rg (electron density) | 14.70 Å |
| Total Rg | 15.87 Å |
| Atom count | 1051 |
| Residues | 124 |
| Excluded volume | 18916 ų |
| Maximum q | 0.500 Å⁻¹ |
| Domain ID domain_id | d5y1ya1 |
| Class class | a — All alpha proteins |
| Fold Fold fold | a.29 — Bromodomain-like |
| Superfamily Superfamily superfamily | a.29.2 — Bromodomain |
| Family Family family | a.29.2.0 — automated matches |
| Domain ID domain_id | d5y1ya2 |
| Class class | l — Artifacts |
| Fold Fold fold | l.1 — Tags |
| Superfamily Superfamily superfamily | l.1.1 — Tags |
| Family Family family | l.1.1.1 — Tags |
| Domain ID domain_id | 5y1yA01 |
| Class class | 1 — Mainly Alpha |
| Architecture architecture | 20 — Up-down Bundle |
| Topology topology | 920 — Histone Acetyltransferase; Chain A |
| Homologous superfamily homologous superfamily | 10 — Bromodomain-like |