6atu

Exploring Cystine Dense Peptide Space to Open a Unique Molecular Toolbox

Method: X-RAY DIFFRACTION

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1. Protein Identity and Related Structures Protein Identity & Related Structures

Elafin

Homo sapiens

UniProt P19957

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein monomer	Monomer	Protein 1	water × 1	Consistent with protein count
10	Protein monomer	Monomer	Protein 1	water × 1	Consistent with protein count
11	Protein monomer	Monomer	Protein 1	water × 1	Consistent with protein count
12	Protein monomer	Monomer	Protein 1	water × 1	Consistent with protein count
13	Protein monomer	Monomer	Protein 1	water × 1	Consistent with protein count
14	Protein monomer	Monomer	Protein 1	water × 1	Consistent with protein count
15	Protein monomer	Monomer	Protein 1	water × 1	Consistent with protein count
16	Protein monomer	Monomer	Protein 1	water × 1	Consistent with protein count
17	Protein monomer	Monomer	Protein 1	water × 1	Consistent with protein count
18	Protein monomer	Monomer	Protein 1	water × 1	Consistent with protein count
19	Protein homooligomer	Homooligomer	Protein 18	water × 18	Consistent with protein count
2	Protein monomer	Monomer	Protein 1	water × 1	Consistent with protein count
3	Protein monomer	Monomer	Protein 1	water × 1	Consistent with protein count
4	Protein monomer	Monomer	Protein 1	water × 1	Consistent with protein count
5	Protein monomer	Monomer	Protein 1	water × 1	Consistent with protein count
6	Protein monomer	Monomer	Protein 1	water × 1	Consistent with protein count
7	Protein monomer	Monomer	Protein 1	water × 1	Consistent with protein count
8	Protein monomer	Monomer	Protein 1	water × 1	Consistent with protein count
9	Protein monomer	Monomer	Protein 1	water × 1	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	ELAF_HUMAN
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain A； PDBConstruct 3–59； UniProt 61–117 Author chain B； PDBConstruct 3–59； UniProt 61–117 Author chain C； PDBConstruct 3–59； UniProt 61–117 Author chain D； PDBConstruct 3–59； UniProt 61–117 Author chain E； PDBConstruct 3–59； UniProt 61–117 Author chain F； PDBConstruct 3–59； UniProt 61–117 Author chain G； PDBConstruct 3–59； UniProt 61–117 Author chain H； PDBConstruct 3–59； UniProt 61–117 Author chain I； PDBConstruct 3–59； UniProt 61–117 Author chain J； PDBConstruct 3–59； UniProt 61–117 Author chain K； PDBConstruct 3–59； UniProt 61–117 Author chain L； PDBConstruct 3–59； UniProt 61–117 Author chain M； PDBConstruct 3–59； UniProt 61–117 Author chain N； PDBConstruct 3–59； UniProt 61–117 Author chain O； PDBConstruct 3–59； UniProt 61–117 Author chain P； PDBConstruct 3–59； UniProt 61–117 Author chain Q； PDBConstruct 3–59； UniProt 61–117 Author chain R； PDBConstruct 3–59； UniProt 61–117

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	6atu
Deposition date deposition_date	2017-08-29
Structure title title	Exploring Cystine Dense Peptide Space to Open a Unique Molecular Toolbox
Keywords keywords	Knottins, Cystine knot, Toxins, TOXIN; TOXIN
Experimental Method method	X-RAY DIFFRACTION

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

6atu__assembly_15__model_1

Assembly 15 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

6atu__assembly_15__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

6atu__assembly_15__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	11.17 Å
Rg (electron density)	10.44 Å
Total Rg	11.73 Å
Atom count	358
Residues	50
Excluded volume	6463 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`6atu__assembly_1__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
2	1	`6atu__assembly_2__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
3	1	`6atu__assembly_3__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
4	1	`6atu__assembly_4__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
5	1	`6atu__assembly_5__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
6	1	`6atu__assembly_6__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
7	1	`6atu__assembly_7__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
8	1	`6atu__assembly_8__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
9	1	`6atu__assembly_9__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
10	1	`6atu__assembly_10__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
11	1	`6atu__assembly_11__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
12	1	`6atu__assembly_12__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
13	1	`6atu__assembly_13__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
14	1	`6atu__assembly_14__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
15	1	`6atu__assembly_15__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
16	1	`6atu__assembly_16__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
17	1	`6atu__assembly_17__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
18	1	`6atu__assembly_18__model_1`	monomeric （1）	Success	4.1.3-1-20251215 (887e7ef)	View Download
19	1	`6atu__assembly_19__model_1`	octadecameric （18）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (2)

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6. Fold Classification (SCOP + CATH) 36 domains

SCOP 2.08 (18 domains)

Domain ID domain_id	d6atua_
Class class	g — Small proteins
Fold Fold fold	g.3 — Knottins (small inhibitors, toxins, lectins)
Superfamily Superfamily superfamily	g.3.14 — Elafin-like
Family Family family	g.3.14.1 — Elafin-like

Domain ID domain_id	d6atub_
Class class	g — Small proteins
Fold Fold fold	g.3 — Knottins (small inhibitors, toxins, lectins)
Superfamily Superfamily superfamily	g.3.14 — Elafin-like
Family Family family	g.3.14.1 — Elafin-like

Domain ID domain_id	d6atuc_
Class class	g — Small proteins
Fold Fold fold	g.3 — Knottins (small inhibitors, toxins, lectins)
Superfamily Superfamily superfamily	g.3.14 — Elafin-like
Family Family family	g.3.14.1 — Elafin-like

Domain ID domain_id	d6atud_
Class class	g — Small proteins
Fold Fold fold	g.3 — Knottins (small inhibitors, toxins, lectins)
Superfamily Superfamily superfamily	g.3.14 — Elafin-like
Family Family family	g.3.14.1 — Elafin-like

Domain ID domain_id	d6atue_
Class class	g — Small proteins
Fold Fold fold	g.3 — Knottins (small inhibitors, toxins, lectins)
Superfamily Superfamily superfamily	g.3.14 — Elafin-like
Family Family family	g.3.14.1 — Elafin-like

Domain ID domain_id	d6atuf_
Class class	g — Small proteins
Fold Fold fold	g.3 — Knottins (small inhibitors, toxins, lectins)
Superfamily Superfamily superfamily	g.3.14 — Elafin-like
Family Family family	g.3.14.1 — Elafin-like

Domain ID domain_id	d6atug_
Class class	g — Small proteins
Fold Fold fold	g.3 — Knottins (small inhibitors, toxins, lectins)
Superfamily Superfamily superfamily	g.3.14 — Elafin-like
Family Family family	g.3.14.1 — Elafin-like

Domain ID domain_id	d6atuh_
Class class	g — Small proteins
Fold Fold fold	g.3 — Knottins (small inhibitors, toxins, lectins)
Superfamily Superfamily superfamily	g.3.14 — Elafin-like
Family Family family	g.3.14.1 — Elafin-like

Domain ID domain_id	d6atui_
Class class	g — Small proteins
Fold Fold fold	g.3 — Knottins (small inhibitors, toxins, lectins)
Superfamily Superfamily superfamily	g.3.14 — Elafin-like
Family Family family	g.3.14.1 — Elafin-like

Domain ID domain_id	d6atuj_
Class class	g — Small proteins
Fold Fold fold	g.3 — Knottins (small inhibitors, toxins, lectins)
Superfamily Superfamily superfamily	g.3.14 — Elafin-like
Family Family family	g.3.14.1 — Elafin-like

Domain ID domain_id	d6atuk_
Class class	g — Small proteins
Fold Fold fold	g.3 — Knottins (small inhibitors, toxins, lectins)
Superfamily Superfamily superfamily	g.3.14 — Elafin-like
Family Family family	g.3.14.1 — Elafin-like

Domain ID domain_id	d6atul_
Class class	g — Small proteins
Fold Fold fold	g.3 — Knottins (small inhibitors, toxins, lectins)
Superfamily Superfamily superfamily	g.3.14 — Elafin-like
Family Family family	g.3.14.1 — Elafin-like

Domain ID domain_id	d6atum_
Class class	g — Small proteins
Fold Fold fold	g.3 — Knottins (small inhibitors, toxins, lectins)
Superfamily Superfamily superfamily	g.3.14 — Elafin-like
Family Family family	g.3.14.1 — Elafin-like

Domain ID domain_id	d6atun_
Class class	g — Small proteins
Fold Fold fold	g.3 — Knottins (small inhibitors, toxins, lectins)
Superfamily Superfamily superfamily	g.3.14 — Elafin-like
Family Family family	g.3.14.1 — Elafin-like

Domain ID domain_id	d6atuo_
Class class	g — Small proteins
Fold Fold fold	g.3 — Knottins (small inhibitors, toxins, lectins)
Superfamily Superfamily superfamily	g.3.14 — Elafin-like
Family Family family	g.3.14.1 — Elafin-like

Domain ID domain_id	d6atup_
Class class	g — Small proteins
Fold Fold fold	g.3 — Knottins (small inhibitors, toxins, lectins)
Superfamily Superfamily superfamily	g.3.14 — Elafin-like
Family Family family	g.3.14.1 — Elafin-like

Domain ID domain_id	d6atuq_
Class class	g — Small proteins
Fold Fold fold	g.3 — Knottins (small inhibitors, toxins, lectins)
Superfamily Superfamily superfamily	g.3.14 — Elafin-like
Family Family family	g.3.14.1 — Elafin-like

Domain ID domain_id	d6atur_
Class class	g — Small proteins
Fold Fold fold	g.3 — Knottins (small inhibitors, toxins, lectins)
Superfamily Superfamily superfamily	g.3.14 — Elafin-like
Family Family family	g.3.14.1 — Elafin-like

CATH v4.4 (18 domains)

Domain ID domain_id	6atuA00
Class class	4 — Few Secondary Structures
Architecture architecture	10 — Irregular
Topology topology	75 — R-elafin
Homologous superfamily homologous superfamily	10 — Elafin-like

Domain ID domain_id	6atuB00
Class class	4 — Few Secondary Structures
Architecture architecture	10 — Irregular
Topology topology	75 — R-elafin
Homologous superfamily homologous superfamily	10 — Elafin-like

Domain ID domain_id	6atuC00
Class class	4 — Few Secondary Structures
Architecture architecture	10 — Irregular
Topology topology	75 — R-elafin
Homologous superfamily homologous superfamily	10 — Elafin-like

Domain ID domain_id	6atuD00
Class class	4 — Few Secondary Structures
Architecture architecture	10 — Irregular
Topology topology	75 — R-elafin
Homologous superfamily homologous superfamily	10 — Elafin-like

Domain ID domain_id	6atuE00
Class class	4 — Few Secondary Structures
Architecture architecture	10 — Irregular
Topology topology	75 — R-elafin
Homologous superfamily homologous superfamily	10 — Elafin-like

Domain ID domain_id	6atuF00
Class class	4 — Few Secondary Structures
Architecture architecture	10 — Irregular
Topology topology	75 — R-elafin
Homologous superfamily homologous superfamily	10 — Elafin-like

Domain ID domain_id	6atuG00
Class class	4 — Few Secondary Structures
Architecture architecture	10 — Irregular
Topology topology	75 — R-elafin
Homologous superfamily homologous superfamily	10 — Elafin-like

Domain ID domain_id	6atuH00
Class class	4 — Few Secondary Structures
Architecture architecture	10 — Irregular
Topology topology	75 — R-elafin
Homologous superfamily homologous superfamily	10 — Elafin-like

Domain ID domain_id	6atuI00
Class class	4 — Few Secondary Structures
Architecture architecture	10 — Irregular
Topology topology	75 — R-elafin
Homologous superfamily homologous superfamily	10 — Elafin-like

Domain ID domain_id	6atuJ00
Class class	4 — Few Secondary Structures
Architecture architecture	10 — Irregular
Topology topology	75 — R-elafin
Homologous superfamily homologous superfamily	10 — Elafin-like

Domain ID domain_id	6atuK00
Class class	4 — Few Secondary Structures
Architecture architecture	10 — Irregular
Topology topology	75 — R-elafin
Homologous superfamily homologous superfamily	10 — Elafin-like

Domain ID domain_id	6atuL00
Class class	4 — Few Secondary Structures
Architecture architecture	10 — Irregular
Topology topology	75 — R-elafin
Homologous superfamily homologous superfamily	10 — Elafin-like

Domain ID domain_id	6atuM00
Class class	4 — Few Secondary Structures
Architecture architecture	10 — Irregular
Topology topology	75 — R-elafin
Homologous superfamily homologous superfamily	10 — Elafin-like

Domain ID domain_id	6atuN00
Class class	4 — Few Secondary Structures
Architecture architecture	10 — Irregular
Topology topology	75 — R-elafin
Homologous superfamily homologous superfamily	10 — Elafin-like

Domain ID domain_id	6atuO00
Class class	4 — Few Secondary Structures
Architecture architecture	10 — Irregular
Topology topology	75 — R-elafin
Homologous superfamily homologous superfamily	10 — Elafin-like

Domain ID domain_id	6atuP00
Class class	4 — Few Secondary Structures
Architecture architecture	10 — Irregular
Topology topology	75 — R-elafin
Homologous superfamily homologous superfamily	10 — Elafin-like

Domain ID domain_id	6atuQ00
Class class	4 — Few Secondary Structures
Architecture architecture	10 — Irregular
Topology topology	75 — R-elafin
Homologous superfamily homologous superfamily	10 — Elafin-like

Domain ID domain_id	6atuR00
Class class	4 — Few Secondary Structures
Architecture architecture	10 — Irregular
Topology topology	75 — R-elafin
Homologous superfamily homologous superfamily	10 — Elafin-like

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Unit-cell length a length_a	71.333 Å
Unit-cell length b length_b	71.333 Å
Unit-cell length c length_c	214.444 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	72

Space group space_group	P 41
Space-group number int_tables_number	76
Crystal system crystal_system	—

Resolution resolution	2.400 Å
Low-resolution limit resolution_low	71.330 Å
R factor r_factor	0.1991
R_work r_work	0.1965
R_free r_free	0.2482

Description description	Elafin
Molecular weight formula_weight	6158.4 kDa
Source method src_method	man
Copy count entity_count	18

Polymer type type	polypeptide(L)
Chain IDs strand_id	A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R
Atom count atom_count	6617

Exploring Cystine Dense Peptide Space to Open a Unique Molecular Toolbox

1. Protein Identity and Related Structures Protein Identity & Related Structures

Elafin

State in the Current Structure

Other States of the Same Protein in the Database

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

6atu__assembly_15__model_1

6atu__assembly_15__model_1 | I(q)

6atu__assembly_15__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (2)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 water

6. Fold Classification (SCOP + CATH) 36 domains

SCOP 2.08 (18 domains)

CATH v4.4 (18 domains)

7. Citations (1)

Source organism organism	Homo sapiens
Common name common_name	Human
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	Homo sapiens

Description description	water
Molecular weight formula_weight	18.0 kDa
Source method src_method	nat
Copy count entity_count	312

Exploring Cystine Dense Peptide Space to Open a Unique Molecular Toolbox

1. Protein Identity and Related Structures Protein Identity & Related Structures

Elafin

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

6atu__assembly_15__model_1

6atu__assembly_15__model_1 | I(q)

6atu__assembly_15__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (2)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 water

6. Fold Classification (SCOP + CATH) 36 domains

SCOP 2.08 (18 domains)

CATH v4.4 (18 domains)

7. Citations (1)