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6bbo

Crystal structure of human APOBEC3H/RNA complex

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

APOBEC3H

Homo sapiens

UniProt B7TQM6

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 2 RNA 2 ;RNA (5'-R(*UP*AP*AP*AP*AP*AP*AP*A)-3') ; × 1 ;RNA (5'-R(*UP*UP*UP*UP*UP*UP*UP*U)-3') ; × 1 MCherry fluorescent protein × 1 （X5DSL3） ZINC ION × 1 GLYCEROL × 1 Consistent with all polymers
2 Protein–RNA Heteromer Protein 2 RNA 2 ;RNA (5'-R(*UP*AP*AP*AP*AP*AP*AP*A)-3') ; × 1 ;RNA (5'-R(*UP*UP*UP*UP*UP*UP*UP*U)-3') ; × 1 MCherry fluorescent protein × 1 （X5DSL3） ZINC ION × 1 GLYCEROL × 1 Consistent with all polymers

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
6b0b 6b0b 6bbo 6bbo

4 assemblies

View Construct and Data Evidence
UniProt name B7TQM6_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–180； UniProt 3–182 Author chain E； PDBConstruct 1–180； UniProt 3–182

MCherry fluorescent protein

Discosoma sp.

UniProt X5DSL3

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 2 RNA 2 APOBEC3H × 1 （B7TQM6） ;RNA (5'-R(*UP*AP*AP*AP*AP*AP*AP*A)-3') ; × 1 ;RNA (5'-R(*UP*UP*UP*UP*UP*UP*UP*U)-3') ; × 1 ZINC ION × 1 GLYCEROL × 1 Consistent with all polymers
2 Protein–RNA Heteromer Protein 2 RNA 2 APOBEC3H × 1 （B7TQM6） ;RNA (5'-R(*UP*AP*AP*AP*AP*AP*AP*A)-3') ; × 1 ;RNA (5'-R(*UP*UP*UP*UP*UP*UP*UP*U)-3') ; × 1 ZINC ION × 1 GLYCEROL × 1 Consistent with all polymers

Other States of the Same Protein in the Database

Monomer
4zin 4zin 4zin 4zio 4zio 4zio

6 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
6bbo 6bbo 6ir1 6ir2 6v00 6wqk 7cxr 7f73 8ilx 8ilx 8im0 8im1

12 assemblies

View Construct and Data Evidence
UniProt name X5DSL3_ANAMA
Isoform —
PDB entities 4
Chains and sequence ranges Author chain D； PDBConstruct 1–219； UniProt 9–227 Author chain H； PDBConstruct 1–219； UniProt 9–227

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id6bbo
Deposition date deposition_date2017-10-19
Structure title titleCrystal structure of human APOBEC3H/RNA complex
Keywords keywordsAPOBEC, deaminase., HYDROLASE, HYDROLASE-RNA complex; HYDROLASE/RNA
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

6bbo__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

6bbo__assembly_1__model_1 | I(q)

10-2 10-1 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

6bbo__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）26.04 Å
Rg (electron density)24.87 Å
Total Rg25.77 Å
Atom count3467
Residues401
Excluded volume60580 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 6bbo__assembly_1__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 6bbo__assembly_2__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (6)

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7. Citations (1)