6bbo

Crystal structure of human APOBEC3H/RNA complex

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

APOBEC3H

Homo sapiens

UniProt B7TQM6

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 2 RNA 2 ;RNA (5'-R(*UP*AP*AP*AP*AP*AP*AP*A)-3') ; × 1 ;RNA (5'-R(*UP*UP*UP*UP*UP*UP*UP*U)-3') ; × 1 MCherry fluorescent protein × 1 (X5DSL3) ZINC ION × 1 GLYCEROL × 1 Consistent with all polymers
2 Protein–RNA Heteromer Protein 2 RNA 2 ;RNA (5'-R(*UP*AP*AP*AP*AP*AP*AP*A)-3') ; × 1 ;RNA (5'-R(*UP*UP*UP*UP*UP*UP*UP*U)-3') ; × 1 MCherry fluorescent protein × 1 (X5DSL3) ZINC ION × 1 GLYCEROL × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name B7TQM6_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 1–180; UniProt 3–182 Author chain E; PDBConstruct 1–180; UniProt 3–182

MCherry fluorescent protein

Discosoma sp.

UniProt X5DSL3

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 2 RNA 2 APOBEC3H × 1 (B7TQM6) ;RNA (5'-R(*UP*AP*AP*AP*AP*AP*AP*A)-3') ; × 1 ;RNA (5'-R(*UP*UP*UP*UP*UP*UP*UP*U)-3') ; × 1 ZINC ION × 1 GLYCEROL × 1 Consistent with all polymers
2 Protein–RNA Heteromer Protein 2 RNA 2 APOBEC3H × 1 (B7TQM6) ;RNA (5'-R(*UP*AP*AP*AP*AP*AP*AP*A)-3') ; × 1 ;RNA (5'-R(*UP*UP*UP*UP*UP*UP*UP*U)-3') ; × 1 ZINC ION × 1 GLYCEROL × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name X5DSL3_ANAMA
Isoform —
PDB entities 4
Chains and sequence ranges Author chain D; PDBConstruct 1–219; UniProt 9–227 Author chain H; PDBConstruct 1–219; UniProt 9–227

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id6bbo
Deposition date deposition_date2017-10-19
Structure title titleCrystal structure of human APOBEC3H/RNA complex
Keywords keywordsAPOBEC, deaminase., HYDROLASE, HYDROLASE-RNA complex; HYDROLASE/RNA
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

6bbo__assembly_2__model_1

Assembly 2 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

6bbo__assembly_2__model_1 | I(q)

10-2 10-1 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

6bbo__assembly_2__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)26.05 Å
Rg (electron density)24.88 Å
Total Rg25.78 Å
Atom count3467
Residues401
Excluded volume60580 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 6bbo__assembly_1__model_1 tetrameric (4) Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 6bbo__assembly_2__model_1 tetrameric (4) Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (6)

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7. Citations (1)