6cft

Structure of Human alpha-Phosphomannomutase 1 containing mutations R180T and R183I

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Phosphomannomutase 1

Homo sapiens

UniProt Q92871

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein monomer Monomer Protein 1 MAGNESIUM ION × 2 water × 1 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name PMM1_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 1–262; UniProt 1–262

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id6cft
Deposition date deposition_date2018-02-17
Structure title titleStructure of Human alpha-Phosphomannomutase 1 containing mutations R180T and R183I
Keywords keywordsphosphatase, haloalkanoate dehalogenase superfamily, mutase, ISOMERASE; ISOMERASE
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

6cft__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

6cft__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

6cft__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)19.93 Å
Rg (electron density)19.20 Å
Total Rg20.10 Å
Atom count1961
Residues245
Excluded volume34881 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 6cft__assembly_1__model_1 monomeric (1) Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

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6. Fold Classification (SCOP + CATH) 3 domains

SCOP 2.08 (1 domains)

Domain ID domain_idd6cfta_
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.108 — HAD-like
Superfamily Superfamily superfamilyc.108.1 — HAD-like
Family Family familyc.108.1.0 — automated matches

CATH v4.4 (2 domains)

Domain ID domain_id6cftA01
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily1000 — HAD superfamily/HAD-like
Domain ID domain_id6cftA02
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology1240 — Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase; Chain: A; domain 2
Homologous superfamily homologous superfamily20 — Eukaryotic phosphomannomutase, cap domain
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7. Citations (1)