Mus musculus
| Assembly | 物理组成 | 蛋白状态 | 分子拷贝数 | 共同组分 | 数据核对 |
|---|---|---|---|---|---|
| 1 | 蛋白同源多聚体 | 同源多聚体 | 蛋白 2 | 2-acetamido-2-deoxy-beta-D-glucopyranose × 6 PROTOPORPHYRIN IX CONTAINING FE × 2 1-PHENYLSULFONAMIDE-3-TRIFLUOROMETHYL-5-PARABROMOPHENYLPYRAZOLE × 2 | 与蛋白数一致 |
| UniProt名称 | PGH2_MOUSE |
| Isoform | — |
| PDB实体 | 1 |
| 链与序列区间 | 作者链 A； PDB构建体 1–587； UniProt 18–604 作者链 B； PDB构建体 1–587； UniProt 18–604 |
页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。
| 条目编号 entry_id | 6cox |
| 沉积日期 deposition_date | 1996-12-18 |
| 结构标题 title | CYCLOOXYGENASE-2 (PROSTAGLANDIN SYNTHASE-2) COMPLEXED WITH A SELECTIVE INHIBITOR, SC-558 IN I222 SPACE GROUP |
| 关键词 keywords | ;PEROXIDASE, DIOXYGENASE, CYCLOOXYGENASE, NONSTEROIDAL ANTIINFLAMMATORY DRUGS, INFLAMMATION, ARTHRITIS, PROSTAGLANDIN, PROSTAGLANDIN SYNTHASE, OXIDOREDUCTASE ;; OXIDOREDUCTASE |
| 实验方法 method | X-RAY DIFFRACTION |
页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 32.03 Å |
| Rg（电子密度） | 31.18 Å |
| 总 Rg | 31.95 Å |
| 原子数 | 9168 |
| 残基数 | 1104 |
| 排除体积 | 163790 ų |
| 最大 q | 0.500 Å⁻¹ |
| 结构域编号 domain_id | d6coxa1 |
| 类 Class class | a — All alpha proteins |
| 折叠类型 Fold fold | a.93 — Heme-dependent peroxidases |
| 超家族 Superfamily superfamily | a.93.1 — Heme-dependent peroxidases |
| 家族 Family family | a.93.1.2 — Myeloperoxidase-like |
| 结构域编号 domain_id | d6coxa2 |
| 类 Class class | g — Small proteins |
| 折叠类型 Fold fold | g.3 — Knottins (small inhibitors, toxins, lectins) |
| 超家族 Superfamily superfamily | g.3.11 — EGF/Laminin |
| 家族 Family family | g.3.11.1 — EGF-type module |
| 结构域编号 domain_id | d6coxb1 |
| 类 Class class | a — All alpha proteins |
| 折叠类型 Fold fold | a.93 — Heme-dependent peroxidases |
| 超家族 Superfamily superfamily | a.93.1 — Heme-dependent peroxidases |
| 家族 Family family | a.93.1.2 — Myeloperoxidase-like |
| 结构域编号 domain_id | d6coxb2 |
| 类 Class class | g — Small proteins |
| 折叠类型 Fold fold | g.3 — Knottins (small inhibitors, toxins, lectins) |
| 超家族 Superfamily superfamily | g.3.11 — EGF/Laminin |
| 家族 Family family | g.3.11.1 — EGF-type module |
| 结构域编号 domain_id | 6coxA01 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 10 — Ribbon |
| 拓扑 Topology topology | 25 — Laminin |
| 同源超家族 H-superfamily homologous superfamily | 10 — Laminin |
| 结构域编号 domain_id | 6coxA02 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 640 — Myeloperoxidase, subunit C |
| 同源超家族 H-superfamily homologous superfamily | 10 — Haem peroxidase domain superfamily, animal type |
| 结构域编号 domain_id | 6coxB01 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 10 — Ribbon |
| 拓扑 Topology topology | 25 — Laminin |
| 同源超家族 H-superfamily homologous superfamily | 10 — Laminin |
| 结构域编号 domain_id | 6coxB02 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 640 — Myeloperoxidase, subunit C |
| 同源超家族 H-superfamily homologous superfamily | 10 — Haem peroxidase domain superfamily, animal type |