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6crs

CryoEM structure of human enterovirus D68 A-particle (pH 7.2 and 4 degrees Celsius)

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

viral protein 1

OrganismNot specified

UniProt A0A097BW12

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 180 viral protein 2 × 60 （A0A1I9KXX3） Consistent with protein count
2 Protein heterocomplex Heteromer Protein 3 viral protein 2 × 1 （A0A1I9KXX3） Consistent with protein count
3 Protein heterocomplex Heteromer Protein 15 viral protein 2 × 5 （A0A1I9KXX3） Consistent with protein count
4 Protein heterocomplex Heteromer Protein 18 viral protein 2 × 6 （A0A1I9KXX3） Consistent with protein count
5 Protein heterocomplex Heteromer Protein 3 viral protein 2 × 1 （A0A1I9KXX3） Consistent with protein count

Other States of the Same Protein in the Database

Monomer
8fl5 8fl5

2 assemblies

Homodimer

None

Homotetramer
7t9p 7t9p 7taf 7taf 7tag 7tag 7tah 7tah 7taj 7taj

10 assemblies

Other homooligomers
7t9p 7t9p 7t9p 7taf 7taf 7taf 7tag 7tag 7tag 7tah 7tah 7tah

15 assemblies; showing the first 12

Heteromeric or nucleic-acid complex
6crp 6crp 6crp 6crp 6crp 6crr 6crr 6crr 6crr 6crr 6crs 6crs

110 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name A0A097BW12_9ENTO
Isoform —
PDB entities 1, 2
Chains and sequence ranges Author chain A； PDBConstruct 1–297； UniProt 565–861 Author chain B； PDBConstruct 1–247； UniProt 318–564

viral protein 2

OrganismNot specified

UniProt A0A1I9KXX3

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 180 viral protein 1 × 60 （A0A097BW12） viral protein 3 × 60 （A0A097BW12） Consistent with protein count
2 Protein heterocomplex Heteromer Protein 3 viral protein 1 × 1 （A0A097BW12） viral protein 3 × 1 （A0A097BW12） Consistent with protein count
3 Protein heterocomplex Heteromer Protein 15 viral protein 1 × 5 （A0A097BW12） viral protein 3 × 5 （A0A097BW12） Consistent with protein count
4 Protein heterocomplex Heteromer Protein 18 viral protein 1 × 6 （A0A097BW12） viral protein 3 × 6 （A0A097BW12） Consistent with protein count
5 Protein heterocomplex Heteromer Protein 3 viral protein 1 × 1 （A0A097BW12） viral protein 3 × 1 （A0A097BW12） Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
6crp 6crp 6crp 6crp 6crp 6crr 6crr 6crr 6crr 6crr 6crs 6crs

55 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name A0A1I9KXX3_9ENTO
Isoform —
PDB entities 3
Chains and sequence ranges Author chain C； PDBConstruct 1–248； UniProt 70–317

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id6crs
Deposition date deposition_date2018-03-19
Structure title titleCryoEM structure of human enterovirus D68 A-particle (pH 7.2 and 4 degrees Celsius)
Keywords keywordsvirus, genome release, acid; VIRUS
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

6crs__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

6crs__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 1010 1011 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

6crs__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）0.00 Å
Rg (electron density)134.80 Å
Total Rg134.90 Å
Atom count324840
Residues41460
Excluded volume5787200 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 6crs__assembly_1__model_1 180-meric （180） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 6crs__assembly_2__model_1 trimeric （3） Excluded — —
Exclusion reason： Auxiliary symmetry representation; not a complete or representative biological assembly.
3 1 6crs__assembly_3__model_1 pentadecameric （15） Excluded — —
Exclusion reason： Auxiliary symmetry representation; not a complete or representative biological assembly.
4 1 6crs__assembly_4__model_1 octadecameric （18） Excluded — —
Exclusion reason： Auxiliary symmetry representation; not a complete or representative biological assembly.
5 1 6crs__assembly_5__model_1 trimeric （3） Excluded — —
Exclusion reason： Auxiliary symmetry representation; not a complete or representative biological assembly.
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

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6. Fold Classification (SCOP + CATH) 3 domains

CATH v4.4 (3 domains)

Domain ID domain_id6crsA00
Class class2 — Mainly Beta
Architecture architecture60 — Sandwich
Topology topology120 — Jelly Rolls
Homologous superfamily homologous superfamily20 —
Domain ID domain_id6crsB00
Class class2 — Mainly Beta
Architecture architecture60 — Sandwich
Topology topology120 — Jelly Rolls
Homologous superfamily homologous superfamily20 —
Domain ID domain_id6crsC00
Class class2 — Mainly Beta
Architecture architecture60 — Sandwich
Topology topology120 — Jelly Rolls
Homologous superfamily homologous superfamily20 —
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7. Citations (1)