Homo sapiens
| Assembly | 物理组成 | 蛋白状态 | 分子拷贝数 | 共同组分 | 数据核对 |
|---|---|---|---|---|---|
| 1 | 蛋白异源复合物 | 异源复合物 | 蛋白 2 | Ubiquitin × 1 （P62979） MAGNESIUM ION × 2 PYROPHOSPHATE 2- × 1 | 与蛋白数一致 |
| 2 | 蛋白异源复合物 | 异源复合物 | 蛋白 2 | Ubiquitin × 1 （P62979） MAGNESIUM ION × 2 PYROPHOSPHATE 2- × 1 | 与蛋白数一致 |
| UniProt名称 | UBA1_HUMAN |
| Isoform | — |
| PDB实体 | 1 |
| 链与序列区间 | 作者链 A； PDB构建体 6–1015； UniProt 49–1058 作者链 C； PDB构建体 6–1015； UniProt 49–1058 |
Homo sapiens
| Assembly | 物理组成 | 蛋白状态 | 分子拷贝数 | 共同组分 | 数据核对 |
|---|---|---|---|---|---|
| 1 | 蛋白异源复合物 | 异源复合物 | 蛋白 2 | Ubiquitin-like modifier-activating enzyme 1 × 1 （P22314） MAGNESIUM ION × 2 PYROPHOSPHATE 2- × 1 | 与蛋白数一致 |
| 2 | 蛋白异源复合物 | 异源复合物 | 蛋白 2 | Ubiquitin-like modifier-activating enzyme 1 × 1 （P22314） MAGNESIUM ION × 2 PYROPHOSPHATE 2- × 1 | 与蛋白数一致 |
| UniProt名称 | RS27A_HUMAN |
| Isoform | — |
| PDB实体 | 2 |
| 链与序列区间 | 作者链 B； PDB构建体 5–80； UniProt 1–76 作者链 D； PDB构建体 5–80； UniProt 1–76 |
页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。
| 条目编号 entry_id | 6dc6 |
| 沉积日期 deposition_date | 2018-05-04 |
| 结构标题 title | Crystal structure of human ubiquitin activating enzyme E1 (Uba1) in complex with ubiquitin |
| 关键词 keywords | Ubiquitin, E1, adenylation, thioester bond, E2, transthiolation, SIGNALING PROTEIN, SIGNALING PROTEIN-LIGASE complex; SIGNALING PROTEIN/LIGASE |
| 实验方法 method | X-RAY DIFFRACTION |
页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 33.81 Å |
| Rg（电子密度） | 32.89 Å |
| 总 Rg | 33.45 Å |
| 原子数 | 8432 |
| 残基数 | 1068 |
| 排除体积 | 149910 ų |
| 最大 q | 0.500 Å⁻¹ |
| 结构域编号 domain_id | d6dc6b_ |
| 类 Class class | d — Alpha and beta proteins (a+b) |
| 折叠类型 Fold fold | d.15 — beta-Grasp (ubiquitin-like) |
| 超家族 Superfamily superfamily | d.15.1 — Ubiquitin-like |
| 家族 Family family | d.15.1.1 — Ubiquitin-related |
| 结构域编号 domain_id | d6dc6d_ |
| 类 Class class | d — Alpha and beta proteins (a+b) |
| 折叠类型 Fold fold | d.15 — beta-Grasp (ubiquitin-like) |
| 超家族 Superfamily superfamily | d.15.1 — Ubiquitin-like |
| 家族 Family family | d.15.1.1 — Ubiquitin-related |
| 结构域编号 domain_id | 6dc6A01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 50 — 3-Layer(bba) Sandwich |
| 拓扑 Topology topology | 50 — FAD/NAD(P)-binding domain |
| 同源超家族 H-superfamily homologous superfamily | 80 — Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 |
| 结构域编号 domain_id | 6dc6A02 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 12550 — Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 2 |
| 结构域编号 domain_id | 6dc6A03 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 40 — Beta Barrel |
| 拓扑 Topology topology | 30 — Elongation Factor Tu (Ef-tu); domain 3 |
| 同源超家族 H-superfamily homologous superfamily | 180 — Ubiquitin-activating enzyme E1, FCCH domain |
| 结构域编号 domain_id | 6dc6A04 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 720 — NAD(P)-binding Rossmann-like Domain |
| 结构域编号 domain_id | 6dc6A05 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 10 — Arc Repressor Mutant, subunit A |
| 同源超家族 H-superfamily homologous superfamily | 2660 — Ubiquitin-activating enzyme E1, SCCH domain |
| 结构域编号 domain_id | 6dc6A06 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 10 — Roll |
| 拓扑 Topology topology | 290 — Structural Genomics Hypothetical 15.5 Kd Protein In mrcA-pckA Intergenic Region; Chain A |
| 同源超家族 H-superfamily homologous superfamily | 60 — Ubiquitin-activating enzyme E1, UFD domain |
| 结构域编号 domain_id | 6dc6C01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 50 — 3-Layer(bba) Sandwich |
| 拓扑 Topology topology | 50 — FAD/NAD(P)-binding domain |
| 同源超家族 H-superfamily homologous superfamily | 80 — Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 |
| 结构域编号 domain_id | 6dc6C02 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 12550 — Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 2 |
| 结构域编号 domain_id | 6dc6C03 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 40 — Beta Barrel |
| 拓扑 Topology topology | 30 — Elongation Factor Tu (Ef-tu); domain 3 |
| 同源超家族 H-superfamily homologous superfamily | 180 — Ubiquitin-activating enzyme E1, FCCH domain |
| 结构域编号 domain_id | 6dc6C04 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 50 — Rossmann fold |
| 同源超家族 H-superfamily homologous superfamily | 720 — NAD(P)-binding Rossmann-like Domain |
| 结构域编号 domain_id | 6dc6C05 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 10 — Arc Repressor Mutant, subunit A |
| 同源超家族 H-superfamily homologous superfamily | 2660 — Ubiquitin-activating enzyme E1, SCCH domain |
| 结构域编号 domain_id | 6dc6C06 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 10 — Roll |
| 拓扑 Topology topology | 290 — Structural Genomics Hypothetical 15.5 Kd Protein In mrcA-pckA Intergenic Region; Chain A |
| 同源超家族 H-superfamily homologous superfamily | 60 — Ubiquitin-activating enzyme E1, UFD domain |