Influenza A virus
| Assembly | 物理组成 | 蛋白状态 | 分子拷贝数 | 共同组分 | 数据核对 |
|---|---|---|---|---|---|
| 1 | 蛋白单体 | 单体 | 蛋白 1 | MANGANESE (II) ION × 2 3-hydroxy-6-[2-methyl-4-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)phenyl]-4-oxo-1,4-dihydropyridine-2-carboxylic acid × 1 1,2-ETHANEDIOL × 1 water × 1 | 与蛋白数一致 |
| UniProt名称 | C3W5S0_I09A0 |
| Isoform | — |
| PDB实体 | 1 |
| 链与序列区间 | 作者链 A； PDB构建体 7–192； UniProt 1–198 |
页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。
| 条目编号 entry_id | 6e4c |
| 沉积日期 deposition_date | 2018-07-17 |
| 结构标题 title | The N-terminal domain of PA endonuclease from the influenza H1N1 virus in complex with 3-hydroxy-6-(2-methyl-4-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)phenyl)-4-oxo-1,4-dihydropyridine-2-carboxylic acid |
| 关键词 keywords | PA endonuclease, inhibitor, influenza, H1N1, HYDROLASE-HYDROLASE INHIBITOR complex; HYDROLASE/HYDROLASE INHIBITOR |
| 实验方法 method | X-RAY DIFFRACTION |
页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 17.16 Å |
| Rg（电子密度） | 15.99 Å |
| 总 Rg | 17.01 Å |
| 原子数 | 1498 |
| 残基数 | 176 |
| 排除体积 | 26633 ų |
| 最大 q | 0.500 Å⁻¹ |
| 结构域编号 domain_id | d6e4ca1 |
| 类 Class class | c — Alpha and beta proteins (a/b) |
| 折叠类型 Fold fold | c.52 — Restriction endonuclease-like |
| 超家族 Superfamily superfamily | c.52.1 — Restriction endonuclease-like |
| 家族 Family family | c.52.1.34 — PA N-terminal domain |
| 结构域编号 domain_id | d6e4ca2 |
| 类 Class class | l — Artifacts |
| 折叠类型 Fold fold | l.1 — Tags |
| 超家族 Superfamily superfamily | l.1.1 — Tags |
| 家族 Family family | l.1.1.1 — Tags |
| 结构域编号 domain_id | 6e4cA00 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| 拓扑 Topology topology | 91 — Restriction Endonuclease |
| 同源超家族 H-superfamily homologous superfamily | 90 — Influenza RNA-dependent RNA polymerase subunit PA, endonuclease domain |