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6h6k

The structure of the FKR mutant of the archaeal translation initiation factor 2 gamma subunit in complex with GDPCP, obtained in the absence of magnesium salts in the crystallization solution.

Method: X-RAY DIFFRACTION
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1. 蛋白身份与相关结构 Protein Identity & Related Structures

Translation initiation factor 2 subunit gamma

Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)

UniProt Q980A5

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白单体 单体 蛋白 1 PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER × 1 SODIUM ION × 3 water × 1 与蛋白数一致
2 蛋白单体 单体 蛋白 1 PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER × 1 SODIUM ION × 3 water × 1 与蛋白数一致
3 蛋白单体 单体 蛋白 1 PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER × 1 1,2-ETHANEDIOL × 3 water × 1 与蛋白数一致
4 蛋白单体 单体 蛋白 1 PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER × 1 1,2-ETHANEDIOL × 1 water × 1 与蛋白数一致
5 蛋白单体 单体 蛋白 1 PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER × 1 water × 1 与蛋白数一致

数据库中的同蛋白其他状态

单体
2plf 2pmd 2pmd 3i1f 3i1f 3pen 3sjz 4m0l 4m0l 4m0l 4m0l 4m0l

共 36 个 assembly，这里只显示前 12 个

同源二聚体

暂无

同源四聚体

暂无

其他同源多聚体

暂无

异源或核酸复合物
2aho 2qmu 2qmu 2qn6 3cw2 3cw2 3cw2 3cw2 3qsy 3v11 6sw9

共 11 个 assembly

查看构建体与数据证据
UniProt名称 IF2G_SULSO
Isoform —
PDB实体 1
链与序列区间 作者链 A； PDB构建体 1–415； UniProt 1–415 作者链 B； PDB构建体 1–415； UniProt 1–415 作者链 C； PDB构建体 1–415； UniProt 1–415 作者链 D； PDB构建体 1–415； UniProt 1–415 作者链 E； PDB构建体 1–415； UniProt 1–415

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。

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2. 结构基本信息 2. Structure Basics

条目编号 entry_id6h6k
沉积日期 deposition_date2018-07-27
结构标题 titleThe structure of the FKR mutant of the archaeal translation initiation factor 2 gamma subunit in complex with GDPCP, obtained in the absence of magnesium salts in the crystallization solution.
关键词 keywords;translation initiation, aIF2, aIF2gamma, aIF2gamma switches, G-protein, GTP-binding domain, translation GTPases, GTP hydrolysis, conformational changes, magnesium ions, TRANSLATION ;; TRANSLATION
实验方法 methodX-RAY DIFFRACTION
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3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

6h6k__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

6h6k__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 个绘图点；横轴和纵轴均采用对数尺度。

6h6k__assembly_1__model_1 | P(r) · Pending

新版 assembly/model P(r) 尚未计算 此处仅保留位置，不展示旧数据 r (Angstrom) P(r)
P(r) 将按相同 assembly/model 分别计算和展示。
Rg（Guinier）23.12 Å
Rg（电子密度）22.03 Å
总 Rg22.97 Å
原子数3221
残基数413
排除体积58178 ų
最大 q0.500 Å⁻¹
Assembly Model 结构单元 聚集说明 状态 CRYSOL 操作
1 1 6h6k__assembly_1__model_1 monomeric （1） 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
2 1 6h6k__assembly_2__model_1 monomeric （1） 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
3 1 6h6k__assembly_3__model_1 monomeric （1） 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
4 1 6h6k__assembly_4__model_1 monomeric （1） 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
5 1 6h6k__assembly_5__model_1 monomeric （1） 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
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4. 晶体学与实验 4. Crystallography & Experiment

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5. 实体与聚合物信息 Entities & Polymers (5)

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6. 折叠分类 (SCOP + CATH) 30 domains

SCOP 2.08 (15 domains)

结构域编号 domain_idd6h6ka1
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamilyc.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family familyc.37.1.8 — G proteins
结构域编号 domain_idd6h6ka2
类 Class classb — All beta proteins
折叠类型 Fold foldb.43 — Reductase/isomerase/elongation factor common domain
超家族 Superfamily superfamilyb.43.3 — Translation proteins
家族 Family familyb.43.3.0 — automated matches
结构域编号 domain_idd6h6ka3
类 Class classb — All beta proteins
折叠类型 Fold foldb.44 — Elongation factor/aminomethyltransferase common domain
超家族 Superfamily superfamilyb.44.1 — EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
家族 Family familyb.44.1.0 — automated matches
结构域编号 domain_idd6h6kb1
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamilyc.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family familyc.37.1.8 — G proteins
结构域编号 domain_idd6h6kb2
类 Class classb — All beta proteins
折叠类型 Fold foldb.43 — Reductase/isomerase/elongation factor common domain
超家族 Superfamily superfamilyb.43.3 — Translation proteins
家族 Family familyb.43.3.0 — automated matches
结构域编号 domain_idd6h6kb3
类 Class classb — All beta proteins
折叠类型 Fold foldb.44 — Elongation factor/aminomethyltransferase common domain
超家族 Superfamily superfamilyb.44.1 — EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
家族 Family familyb.44.1.0 — automated matches
结构域编号 domain_idd6h6kc1
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamilyc.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family familyc.37.1.8 — G proteins
结构域编号 domain_idd6h6kc2
类 Class classb — All beta proteins
折叠类型 Fold foldb.43 — Reductase/isomerase/elongation factor common domain
超家族 Superfamily superfamilyb.43.3 — Translation proteins
家族 Family familyb.43.3.0 — automated matches
结构域编号 domain_idd6h6kc3
类 Class classb — All beta proteins
折叠类型 Fold foldb.44 — Elongation factor/aminomethyltransferase common domain
超家族 Superfamily superfamilyb.44.1 — EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
家族 Family familyb.44.1.0 — automated matches
结构域编号 domain_idd6h6kd1
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamilyc.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family familyc.37.1.8 — G proteins
结构域编号 domain_idd6h6kd2
类 Class classb — All beta proteins
折叠类型 Fold foldb.43 — Reductase/isomerase/elongation factor common domain
超家族 Superfamily superfamilyb.43.3 — Translation proteins
家族 Family familyb.43.3.0 — automated matches
结构域编号 domain_idd6h6kd3
类 Class classb — All beta proteins
折叠类型 Fold foldb.44 — Elongation factor/aminomethyltransferase common domain
超家族 Superfamily superfamilyb.44.1 — EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
家族 Family familyb.44.1.0 — automated matches
结构域编号 domain_idd6h6ke1
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamilyc.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family familyc.37.1.8 — G proteins
结构域编号 domain_idd6h6ke2
类 Class classb — All beta proteins
折叠类型 Fold foldb.43 — Reductase/isomerase/elongation factor common domain
超家族 Superfamily superfamilyb.43.3 — Translation proteins
家族 Family familyb.43.3.0 — automated matches
结构域编号 domain_idd6h6ke3
类 Class classb — All beta proteins
折叠类型 Fold foldb.44 — Elongation factor/aminomethyltransferase common domain
超家族 Superfamily superfamilyb.44.1 — EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
家族 Family familyb.44.1.0 — automated matches

CATH v4.4 (15 domains)

结构域编号 domain_id6h6kA01
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily300 — P-loop containing nucleotide triphosphate hydrolases
结构域编号 domain_id6h6kA02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology30 — Elongation Factor Tu (Ef-tu); domain 3
同源超家族 H-superfamily homologous superfamily10 — Translation factors
结构域编号 domain_id6h6kA03
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology30 — Elongation Factor Tu (Ef-tu); domain 3
同源超家族 H-superfamily homologous superfamily10 — Translation factors
结构域编号 domain_id6h6kB01
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily300 — P-loop containing nucleotide triphosphate hydrolases
结构域编号 domain_id6h6kB02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology30 — Elongation Factor Tu (Ef-tu); domain 3
同源超家族 H-superfamily homologous superfamily10 — Translation factors
结构域编号 domain_id6h6kB03
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology30 — Elongation Factor Tu (Ef-tu); domain 3
同源超家族 H-superfamily homologous superfamily10 — Translation factors
结构域编号 domain_id6h6kC01
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily300 — P-loop containing nucleotide triphosphate hydrolases
结构域编号 domain_id6h6kC02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology30 — Elongation Factor Tu (Ef-tu); domain 3
同源超家族 H-superfamily homologous superfamily10 — Translation factors
结构域编号 domain_id6h6kC03
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology30 — Elongation Factor Tu (Ef-tu); domain 3
同源超家族 H-superfamily homologous superfamily10 — Translation factors
结构域编号 domain_id6h6kD01
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily300 — P-loop containing nucleotide triphosphate hydrolases
结构域编号 domain_id6h6kD02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology30 — Elongation Factor Tu (Ef-tu); domain 3
同源超家族 H-superfamily homologous superfamily10 — Translation factors
结构域编号 domain_id6h6kD03
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology30 — Elongation Factor Tu (Ef-tu); domain 3
同源超家族 H-superfamily homologous superfamily10 — Translation factors
结构域编号 domain_id6h6kE01
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily300 — P-loop containing nucleotide triphosphate hydrolases
结构域编号 domain_id6h6kE02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology30 — Elongation Factor Tu (Ef-tu); domain 3
同源超家族 H-superfamily homologous superfamily10 — Translation factors
结构域编号 domain_id6h6kE03
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology30 — Elongation Factor Tu (Ef-tu); domain 3
同源超家族 H-superfamily homologous superfamily10 — Translation factors
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7. 引用文献 (5)