6ppe

ClpP and ClpX IGF loop in ClpX-ClpP complex with D7 symmetry

Method: ELECTRON MICROSCOPY
▼

1. 蛋白身份与相关结构 Protein Identity & Related Structures

ATP-dependent Clp protease proteolytic subunit

Escherichia coli

UniProt A0A0K4NM46

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 28 ATP-dependent Clp protease ATP-binding subunit ClpX × 14 (A0A1Q9L861) water × 14 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 A0A0K4NM46_ECOLX
Isoform —
PDB实体 1
链与序列区间 作者链 A; PDB构建体 1–192; UniProt 16–207 作者链 B; PDB构建体 1–192; UniProt 16–207 作者链 C; PDB构建体 1–192; UniProt 16–207 作者链 D; PDB构建体 1–192; UniProt 16–207 作者链 E; PDB构建体 1–192; UniProt 16–207 作者链 F; PDB构建体 1–192; UniProt 16–207 作者链 G; PDB构建体 1–192; UniProt 16–207 作者链 H; PDB构建体 1–192; UniProt 16–207 作者链 I; PDB构建体 1–192; UniProt 16–207 作者链 J; PDB构建体 1–192; UniProt 16–207 作者链 K; PDB构建体 1–192; UniProt 16–207 作者链 L; PDB构建体 1–192; UniProt 16–207 作者链 M; PDB构建体 1–192; UniProt 16–207 作者链 N; PDB构建体 1–192; UniProt 16–207

ATP-dependent Clp protease ATP-binding subunit ClpX

Escherichia coli

UniProt A0A1Q9L861

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 28 ATP-dependent Clp protease proteolytic subunit × 14 (A0A0K4NM46) water × 14 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 A0A1Q9L861_ECOLX
Isoform —
PDB实体 2
链与序列区间 作者链 1; PDB构建体 1–363; UniProt 62–424 作者链 2; PDB构建体 1–363; UniProt 62–424 作者链 3; PDB构建体 1–363; UniProt 62–424 作者链 O; PDB构建体 1–363; UniProt 62–424 作者链 P; PDB构建体 1–363; UniProt 62–424 作者链 Q; PDB构建体 1–363; UniProt 62–424 作者链 R; PDB构建体 1–363; UniProt 62–424 作者链 S; PDB构建体 1–363; UniProt 62–424 作者链 T; PDB构建体 1–363; UniProt 62–424 作者链 U; PDB构建体 1–363; UniProt 62–424 作者链 V; PDB构建体 1–363; UniProt 62–424 作者链 X; PDB构建体 1–363; UniProt 62–424 作者链 Y; PDB构建体 1–363; UniProt 62–424 作者链 Z; PDB构建体 1–363; UniProt 62–424

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中;数据库内部编号、导入时间和 assembly 操作表达式仅用于维护,因此不在读者页面展示。

▼

2. 结构基本信息 2. Structure Basics

条目编号 entry_id6ppe
沉积日期 deposition_date2019-07-06
结构标题 titleClpP and ClpX IGF loop in ClpX-ClpP complex with D7 symmetry
关键词 keywordsProtein degradation, AAA+ protease complex, CHAPERONE; CHAPERONE
实验方法 methodELECTRON MICROSCOPY
▼

3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

6ppe__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

6ppe__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 q (1/Angstrom) I(q)
100 个绘图点;横轴和纵轴均采用对数尺度。

6ppe__assembly_1__model_1 | P(r) · Pending

新版 assembly/model P(r) 尚未计算 此处仅保留位置,不展示旧数据 r (Angstrom) P(r)
P(r) 将按相同 assembly/model 分别计算和展示。
Rg(Guinier)44.80 Å
Rg(电子密度)43.65 Å
总 Rg43.99 Å
原子数43722
残基数2814
排除体积390150 ų
最大 q0.500 Å⁻¹
Assembly Model 结构单元 聚集说明 状态 CRYSOL 操作
1 1 6ppe__assembly_1__model_1 28-meric (28) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
▶

4. 晶体学与实验 4. Crystallography & Experiment

▶

5. 实体与聚合物信息 Entities & Polymers (3)

▼

6. 折叠分类 (SCOP + CATH) 42 domains

SCOP 2.08 (28 domains)

结构域编号 domain_idd6ppe1_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamilyc.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family familyc.37.1.20 — Extended AAA-ATPase domain
结构域编号 domain_idd6ppe2_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamilyc.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family familyc.37.1.20 — Extended AAA-ATPase domain
结构域编号 domain_idd6ppe3_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamilyc.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family familyc.37.1.20 — Extended AAA-ATPase domain
结构域编号 domain_idd6ppea_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.14 — ClpP/crotonase
超家族 Superfamily superfamilyc.14.1 — ClpP/crotonase
家族 Family familyc.14.1.1 — Clp protease, ClpP subunit
结构域编号 domain_idd6ppeb_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.14 — ClpP/crotonase
超家族 Superfamily superfamilyc.14.1 — ClpP/crotonase
家族 Family familyc.14.1.1 — Clp protease, ClpP subunit
结构域编号 domain_idd6ppec_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.14 — ClpP/crotonase
超家族 Superfamily superfamilyc.14.1 — ClpP/crotonase
家族 Family familyc.14.1.1 — Clp protease, ClpP subunit
结构域编号 domain_idd6pped_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.14 — ClpP/crotonase
超家族 Superfamily superfamilyc.14.1 — ClpP/crotonase
家族 Family familyc.14.1.1 — Clp protease, ClpP subunit
结构域编号 domain_idd6ppee_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.14 — ClpP/crotonase
超家族 Superfamily superfamilyc.14.1 — ClpP/crotonase
家族 Family familyc.14.1.1 — Clp protease, ClpP subunit
结构域编号 domain_idd6ppef_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.14 — ClpP/crotonase
超家族 Superfamily superfamilyc.14.1 — ClpP/crotonase
家族 Family familyc.14.1.1 — Clp protease, ClpP subunit
结构域编号 domain_idd6ppeg_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.14 — ClpP/crotonase
超家族 Superfamily superfamilyc.14.1 — ClpP/crotonase
家族 Family familyc.14.1.1 — Clp protease, ClpP subunit
结构域编号 domain_idd6ppeh_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.14 — ClpP/crotonase
超家族 Superfamily superfamilyc.14.1 — ClpP/crotonase
家族 Family familyc.14.1.1 — Clp protease, ClpP subunit
结构域编号 domain_idd6ppei_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.14 — ClpP/crotonase
超家族 Superfamily superfamilyc.14.1 — ClpP/crotonase
家族 Family familyc.14.1.1 — Clp protease, ClpP subunit
结构域编号 domain_idd6ppej_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.14 — ClpP/crotonase
超家族 Superfamily superfamilyc.14.1 — ClpP/crotonase
家族 Family familyc.14.1.1 — Clp protease, ClpP subunit
结构域编号 domain_idd6ppek_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.14 — ClpP/crotonase
超家族 Superfamily superfamilyc.14.1 — ClpP/crotonase
家族 Family familyc.14.1.1 — Clp protease, ClpP subunit
结构域编号 domain_idd6ppel_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.14 — ClpP/crotonase
超家族 Superfamily superfamilyc.14.1 — ClpP/crotonase
家族 Family familyc.14.1.1 — Clp protease, ClpP subunit
结构域编号 domain_idd6ppem_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.14 — ClpP/crotonase
超家族 Superfamily superfamilyc.14.1 — ClpP/crotonase
家族 Family familyc.14.1.1 — Clp protease, ClpP subunit
结构域编号 domain_idd6ppen_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.14 — ClpP/crotonase
超家族 Superfamily superfamilyc.14.1 — ClpP/crotonase
家族 Family familyc.14.1.1 — Clp protease, ClpP subunit
结构域编号 domain_idd6ppeo_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamilyc.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family familyc.37.1.20 — Extended AAA-ATPase domain
结构域编号 domain_idd6ppep_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamilyc.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family familyc.37.1.20 — Extended AAA-ATPase domain
结构域编号 domain_idd6ppeq_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamilyc.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family familyc.37.1.20 — Extended AAA-ATPase domain
结构域编号 domain_idd6pper_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamilyc.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family familyc.37.1.20 — Extended AAA-ATPase domain
结构域编号 domain_idd6ppes_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamilyc.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family familyc.37.1.20 — Extended AAA-ATPase domain
结构域编号 domain_idd6ppet_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamilyc.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family familyc.37.1.20 — Extended AAA-ATPase domain
结构域编号 domain_idd6ppeu_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamilyc.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family familyc.37.1.20 — Extended AAA-ATPase domain
结构域编号 domain_idd6ppev_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamilyc.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family familyc.37.1.20 — Extended AAA-ATPase domain
结构域编号 domain_idd6ppex_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamilyc.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family familyc.37.1.20 — Extended AAA-ATPase domain
结构域编号 domain_idd6ppey_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamilyc.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family familyc.37.1.20 — Extended AAA-ATPase domain
结构域编号 domain_idd6ppez_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamilyc.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family familyc.37.1.20 — Extended AAA-ATPase domain

CATH v4.4 (14 domains)

结构域编号 domain_id6ppeA00
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology226 — 2-enoyl-CoA Hydratase; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily10 — 2-enoyl-CoA Hydratase; Chain A, domain 1
结构域编号 domain_id6ppeB00
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology226 — 2-enoyl-CoA Hydratase; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily10 — 2-enoyl-CoA Hydratase; Chain A, domain 1
结构域编号 domain_id6ppeC00
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology226 — 2-enoyl-CoA Hydratase; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily10 — 2-enoyl-CoA Hydratase; Chain A, domain 1
结构域编号 domain_id6ppeD00
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology226 — 2-enoyl-CoA Hydratase; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily10 — 2-enoyl-CoA Hydratase; Chain A, domain 1
结构域编号 domain_id6ppeE00
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology226 — 2-enoyl-CoA Hydratase; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily10 — 2-enoyl-CoA Hydratase; Chain A, domain 1
结构域编号 domain_id6ppeF00
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology226 — 2-enoyl-CoA Hydratase; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily10 — 2-enoyl-CoA Hydratase; Chain A, domain 1
结构域编号 domain_id6ppeG00
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology226 — 2-enoyl-CoA Hydratase; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily10 — 2-enoyl-CoA Hydratase; Chain A, domain 1
结构域编号 domain_id6ppeH00
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology226 — 2-enoyl-CoA Hydratase; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily10 — 2-enoyl-CoA Hydratase; Chain A, domain 1
结构域编号 domain_id6ppeI00
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology226 — 2-enoyl-CoA Hydratase; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily10 — 2-enoyl-CoA Hydratase; Chain A, domain 1
结构域编号 domain_id6ppeJ00
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology226 — 2-enoyl-CoA Hydratase; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily10 — 2-enoyl-CoA Hydratase; Chain A, domain 1
结构域编号 domain_id6ppeK00
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology226 — 2-enoyl-CoA Hydratase; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily10 — 2-enoyl-CoA Hydratase; Chain A, domain 1
结构域编号 domain_id6ppeL00
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology226 — 2-enoyl-CoA Hydratase; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily10 — 2-enoyl-CoA Hydratase; Chain A, domain 1
结构域编号 domain_id6ppeM00
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology226 — 2-enoyl-CoA Hydratase; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily10 — 2-enoyl-CoA Hydratase; Chain A, domain 1
结构域编号 domain_id6ppeN00
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology226 — 2-enoyl-CoA Hydratase; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily10 — 2-enoyl-CoA Hydratase; Chain A, domain 1
▶

7. 引用文献 (1)