6snj

Solution structure of the FUS/TLS RNA recognition motif in complex with U1 snRNA stem loop III

Method: SOLUTION NMR

1. Protein Identity and Related Structures Protein Identity & Related Structures

RNA-binding protein FUS

Homo sapiens

UniProt P35637

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Monomer Protein 1 RNA 1 U1 snRNA stem loop III, RNA (28-MER) × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name FUS_HUMAN
Isoform P35637-2
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 1–131; UniProt 259–389

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

2. Structure Basics 2. Structure Basics

Entry ID entry_id6snj
Deposition date deposition_date2019-08-26
Structure title titleSolution structure of the FUS/TLS RNA recognition motif in complex with U1 snRNA stem loop III
Keywords keywordsSplicing regulation, FUS-U1snRNP, Spliceosome, SPLICING; SPLICING
Experimental Method methodSOLUTION NMR

3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

6snj__assembly_1__model_3

Assembly 1 · Model 3 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

6snj__assembly_1__model_3 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

6snj__assembly_1__model_3 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)19.23 Å
Rg (electron density)18.37 Å
Total Rg19.11 Å
Atom count2840
Residues159
Excluded volume25642 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 6snj__assembly_1__model_1 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
1 2 6snj__assembly_1__model_2 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
1 3 6snj__assembly_1__model_3 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
1 4 6snj__assembly_1__model_4 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
1 5 6snj__assembly_1__model_5 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
1 6 6snj__assembly_1__model_6 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
1 7 6snj__assembly_1__model_7 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
1 8 6snj__assembly_1__model_8 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
1 9 6snj__assembly_1__model_9 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
1 10 6snj__assembly_1__model_10 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
1 11 6snj__assembly_1__model_11 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
1 12 6snj__assembly_1__model_12 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
1 13 6snj__assembly_1__model_13 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
1 14 6snj__assembly_1__model_14 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
1 15 6snj__assembly_1__model_15 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
1 16 6snj__assembly_1__model_16 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
1 17 6snj__assembly_1__model_17 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
1 18 6snj__assembly_1__model_18 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download

4. Crystallography and Experiment 4. Crystallography & Experiment

5. Entities and Polymers Entities & Polymers (2)

6. Fold Classification (SCOP + CATH) 1 domains

SCOP 2.08 (1 domains)

Domain ID domain_idd6snja_
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.58 — Ferredoxin-like
Superfamily Superfamily superfamilyd.58.7 — RNA-binding domain, RBD, aka RNA recognition motif (RRM)
Family Family familyd.58.7.0 — automated matches

7. Citations (1)