← Back to search
6t2l

Streptavidin variants harbouring an artificial organocatalyst based cofactor

Method: X-RAY DIFFRACTION
▼

1. Protein Identity and Related Structures Protein Identity & Related Structures

Streptavidin

Streptomyces avidinii

UniProt P22629

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 4 ;5-[(3~{a}~{S},4~{S},6~{a}~{R})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-d]imidazol-4-yl]-~{N}-(1-pyridin-4-ylpiperidin-4-yl)pentanamide ; × 4 1,2-ETHANEDIOL × 4 GLYCEROL × 4 water × 4 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
3rdm 3rdo 3rdq 3rds 3rdu 3re5 3re6 5n8t 7dy0 7dy0 7efc 7efc

14 assemblies; showing the first 12

Homodimer
1mm9 1moy 1swg 1swg 3rdx 5cse 6s4q 6s50 6uc3 6ud1 6ud6 8xg4

17 assemblies; showing the first 12

Homotetramer
1df8 1i9h 1kff 1kl4 1lcv 1lcw 1lcz 1mep 1mk5 1mm9 1mm9 1moy

262 assemblies; showing the first 12

Other homooligomers
1df8 1lcv 1lcz 1sre 1srg 1sri 2izc 2izd 2ize 2rth 2rti 2rtn

16 assemblies; showing the first 12

Heteromeric or nucleic-acid complex
1hqq 1hxl 1hxz 1hy2 1kl3 1kl5 1pts 1pts 1rst 1rsu 1sld 1sle

60 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name SAV_STRAV
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 14–159； UniProt 38–183

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

▼

2. Structure Basics 2. Structure Basics

Entry ID entry_id6t2l
Deposition date deposition_date2019-10-09
Structure title titleStreptavidin variants harbouring an artificial organocatalyst based cofactor
Keywords keywordsartificial cofactor, streptavidin, catalyst, Biotin-binding protein; biotin-binding protein
Experimental Method methodX-RAY DIFFRACTION
▼

3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

6t2l__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

6t2l__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

6t2l__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）22.47 Å
Rg (electron density)21.42 Å
Total Rg22.41 Å
Atom count7196
Residues480
Excluded volume64702 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 6t2l__assembly_1__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
▶

4. Crystallography and Experiment 4. Crystallography & Experiment

▶

5. Entities and Polymers Entities & Polymers (5)

▼

6. Fold Classification (SCOP + CATH) 1 domains

SCOP 2.08 (1 domains)

Domain ID domain_idd6t2la_
Class classb — All beta proteins
Fold Fold foldb.61 — Streptavidin-like
Superfamily Superfamily superfamilyb.61.1 — Avidin/streptavidin
Family Family familyb.61.1.1 — Avidin/streptavidin
▶

7. Citations (1)