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6u9d

Saccharomyces cerevisiae acetohydroxyacid synthase

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Acetolactate synthase catalytic subunit, mitochondrial

Saccharomyces cerevisiae

UniProt P07342

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 16 Acetolactate synthase small subunit, mitochondrial × 8 （B3LU66） THIAMINE DIPHOSPHATE × 8 MAGNESIUM ION × 12 FLAVIN-ADENINE DINUCLEOTIDE × 8 methyl 2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoylmethyl]benzoate × 8 ADENOSINE-5'-TRIPHOSPHATE × 8 water × 9 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 16 Acetolactate synthase small subunit, mitochondrial × 8 （B3LU66） THIAMINE DIPHOSPHATE × 6 MAGNESIUM ION × 8 FLAVIN-ADENINE DINUCLEOTIDE × 8 methyl 2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoylmethyl]benzoate × 8 ADENOSINE-5'-TRIPHOSPHATE × 8 water × 10 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer
1jsc 1n0h 1t9a 1t9b 1t9c 1t9d 1t9d 5fem 5ims 5wkc 5wkc 6bd3

13 assemblies; showing the first 12

Homotetramer

None

Other homooligomers
1t9a

1 assemblies

Heteromeric or nucleic-acid complex
6u9d 6u9d

2 assemblies

View Construct and Data Evidence
UniProt name ILVB_YEAST
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 15–644； UniProt 58–687 Author chain B； PDBConstruct 15–644； UniProt 58–687 Author chain E； PDBConstruct 15–644； UniProt 58–687 Author chain F； PDBConstruct 15–644； UniProt 58–687 Author chain I； PDBConstruct 15–644； UniProt 58–687 Author chain J； PDBConstruct 15–644； UniProt 58–687 Author chain M； PDBConstruct 15–644； UniProt 58–687 Author chain N； PDBConstruct 15–644； UniProt 58–687 Author chain Q； PDBConstruct 15–644； UniProt 58–687 Author chain R； PDBConstruct 15–644； UniProt 58–687 Author chain U； PDBConstruct 15–644； UniProt 58–687 Author chain V； PDBConstruct 15–644； UniProt 58–687

Acetolactate synthase small subunit, mitochondrial

Saccharomyces cerevisiae

UniProt B3LU66

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 16 Acetolactate synthase catalytic subunit, mitochondrial × 8 （P07342） THIAMINE DIPHOSPHATE × 8 MAGNESIUM ION × 12 FLAVIN-ADENINE DINUCLEOTIDE × 8 methyl 2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoylmethyl]benzoate × 8 ADENOSINE-5'-TRIPHOSPHATE × 8 water × 9 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 16 Acetolactate synthase catalytic subunit, mitochondrial × 8 （P07342） THIAMINE DIPHOSPHATE × 6 MAGNESIUM ION × 8 FLAVIN-ADENINE DINUCLEOTIDE × 8 methyl 2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoylmethyl]benzoate × 8 ADENOSINE-5'-TRIPHOSPHATE × 8 water × 10 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
6u9d 6u9d

2 assemblies

View Construct and Data Evidence
UniProt name B3LU66_YEAS1
Isoform —
PDB entities 2
Chains and sequence ranges Author chain C； PDBConstruct 29–297； UniProt 41–309 Author chain D； PDBConstruct 29–297； UniProt 41–309 Author chain G； PDBConstruct 29–297； UniProt 41–309 Author chain H； PDBConstruct 29–297； UniProt 41–309 Author chain K； PDBConstruct 29–297； UniProt 41–309 Author chain L； PDBConstruct 29–297； UniProt 41–309 Author chain O； PDBConstruct 29–297； UniProt 41–309 Author chain P； PDBConstruct 29–297； UniProt 41–309 Author chain S； PDBConstruct 29–297； UniProt 41–309 Author chain T； PDBConstruct 29–297； UniProt 41–309 Author chain W； PDBConstruct 29–297； UniProt 41–309 Author chain X； PDBConstruct 29–297； UniProt 41–309

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id6u9d
Deposition date deposition_date2019-09-08
Structure title titleSaccharomyces cerevisiae acetohydroxyacid synthase
Keywords keywordsAHAS, pyruvate, FAD, dioxygen, TRANSFERASE; TRANSFERASE
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

6u9d__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

6u9d__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

6u9d__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）66.91 Å
Rg (electron density)67.11 Å
Total Rg66.99 Å
Atom count53050
Residues6820
Excluded volume941200 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 6u9d__assembly_1__model_1 hexadecameric （16） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 6u9d__assembly_2__model_1 hexadecameric （16） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (8)

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6. Fold Classification (SCOP + CATH) 28 domains

SCOP 2.08 (1 domains)

Domain ID domain_idd6u9dr1
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.36 — Thiamin diphosphate-binding fold (THDP-binding)
Superfamily Superfamily superfamilyc.36.1 — Thiamin diphosphate-binding fold (THDP-binding)
Family Family familyc.36.1.0 — automated matches

CATH v4.4 (27 domains)

Domain ID domain_id6u9dA01
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily970 — Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains
Domain ID domain_id6u9dA02
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily1220 — TPP-binding domain
Domain ID domain_id6u9dA03
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily970 — Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains
Domain ID domain_id6u9dB01
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily970 — Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains
Domain ID domain_id6u9dB02
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily1220 — TPP-binding domain
Domain ID domain_id6u9dB03
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily970 — Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains
Domain ID domain_id6u9dE01
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily970 — Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains
Domain ID domain_id6u9dE02
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily1220 — TPP-binding domain
Domain ID domain_id6u9dE03
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily970 — Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains
Domain ID domain_id6u9dF01
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily970 — Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains
Domain ID domain_id6u9dF02
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily1220 — TPP-binding domain
Domain ID domain_id6u9dF03
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily970 — Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains
Domain ID domain_id6u9dJ01
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily970 — Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains
Domain ID domain_id6u9dJ02
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily1220 — TPP-binding domain
Domain ID domain_id6u9dJ03
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily970 — Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains
Domain ID domain_id6u9dM01
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily970 — Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains
Domain ID domain_id6u9dM02
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily1220 — TPP-binding domain
Domain ID domain_id6u9dM03
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily970 — Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains
Domain ID domain_id6u9dN01
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily970 — Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains
Domain ID domain_id6u9dN02
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily1220 — TPP-binding domain
Domain ID domain_id6u9dN03
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily970 — Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains
Domain ID domain_id6u9dU01
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily970 — Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains
Domain ID domain_id6u9dU02
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily1220 — TPP-binding domain
Domain ID domain_id6u9dU03
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily970 — Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains
Domain ID domain_id6u9dV01
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily970 — Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains
Domain ID domain_id6u9dV02
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily1220 — TPP-binding domain
Domain ID domain_id6u9dV03
Class class3 — Alpha Beta
Architecture architecture40 — 3-Layer(aba) Sandwich
Topology topology50 — Rossmann fold
Homologous superfamily homologous superfamily970 — Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains
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7. Citations (1)