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6wfs

Cryo-EM Structure of Hepatitis B virus T=4 capsid in complex with the antiviral molecule DBT1

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Capsid protein

Hepatitis B virus genotype D subtype adw

UniProt P03147

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 240 11-oxo-N-[2-(4-sulfamoylphenyl)ethyl]-10,11-dihydrodibenzo[b,f][1,4]thiazepine-8-carboxamide × 240 Consistent with protein count
2 Protein homooligomer Homooligomer Protein 4 11-oxo-N-[2-(4-sulfamoylphenyl)ethyl]-10,11-dihydrodibenzo[b,f][1,4]thiazepine-8-carboxamide × 4 Consistent with protein count
3 Protein homooligomer Homooligomer Protein 20 11-oxo-N-[2-(4-sulfamoylphenyl)ethyl]-10,11-dihydrodibenzo[b,f][1,4]thiazepine-8-carboxamide × 20 Consistent with protein count
4 Protein homooligomer Homooligomer Protein 24 11-oxo-N-[2-(4-sulfamoylphenyl)ethyl]-10,11-dihydrodibenzo[b,f][1,4]thiazepine-8-carboxamide × 24 Consistent with protein count
5 Protein homooligomer Homooligomer Protein 4 11-oxo-N-[2-(4-sulfamoylphenyl)ethyl]-10,11-dihydrodibenzo[b,f][1,4]thiazepine-8-carboxamide × 4 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer
3kxs 3kxs 3kxs 4bmg 4bmg 4bmg 7k5m 7k5m 7k5m 9n3h

10 assemblies

Homotetramer
2g33 2g33 2g34 2g34 2qij 2qij 4g93 4g93 5d7y 5d7y 6bvf 6bvf

18 assemblies; showing the first 12

Other homooligomers
2g33 2g33 2g33 2g33 2g34 2g34 2g34 2g34 2qij 2qij 2qij 2qij

43 assemblies; showing the first 12

Heteromeric or nucleic-acid complex
6cwd 6cwd 6cwt

3 assemblies

View Construct and Data Evidence
UniProt name CAPSD_HBVD1
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–149； UniProt 1–149 Author chain B； PDBConstruct 1–149； UniProt 1–149 Author chain C； PDBConstruct 1–149； UniProt 1–149 Author chain D； PDBConstruct 1–149； UniProt 1–149

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id6wfs
Deposition date deposition_date2020-04-03
Structure title titleCryo-EM Structure of Hepatitis B virus T=4 capsid in complex with the antiviral molecule DBT1
Keywords keywordscapsid, antiviral, HBV, VIRUS LIKE PARTICLE; VIRUS LIKE PARTICLE
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

6wfs__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

6wfs__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 1010 1011 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

6wfs__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）0.00 Å
Rg (electron density)147.40 Å
Total Rg147.60 Å
Atom count279360
Residues34080
Excluded volume4979500 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 6wfs__assembly_1__model_1 240-meric （240） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 6wfs__assembly_2__model_1 tetrameric （4） Excluded — —
Exclusion reason： Auxiliary symmetry representation; not a complete or representative biological assembly.
3 1 6wfs__assembly_3__model_1 eicosameric （20） Excluded — —
Exclusion reason： Auxiliary symmetry representation; not a complete or representative biological assembly.
4 1 6wfs__assembly_4__model_1 24-meric （24） Excluded — —
Exclusion reason： Auxiliary symmetry representation; not a complete or representative biological assembly.
5 1 6wfs__assembly_5__model_1 tetrameric （4） Excluded — —
Exclusion reason： Auxiliary symmetry representation; not a complete or representative biological assembly.
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (2)

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7. Citations (1)