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6xa8

Crystal Structure of Human Scribble PDZ1:Vangl2 complex

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Protein scribble homolog

Homo sapiens

UniProt Q14160

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 2 C-terminal peptide of Vangl2 × 1 1,2-ETHANEDIOL × 1 PHOSPHATE ION × 2 water × 2 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 2 C-terminal peptide of Vangl2 × 1 1,2-ETHANEDIOL × 2 PHOSPHATE ION × 2 water × 2 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1uju 1wha 1x5q 2w4f 4wyt 5vwc 6eey 6esp 6myf

9 assemblies

Homodimer
7jo7 7jo7 7qsb

3 assemblies

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
4wyu 4wyu 5vwi 5vwi 5vwi 5vwk 5vwk 5vwk 5vwk 6ms1 6ms1 6mtu

47 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name SCRIB_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 6–122； UniProt 700–816 Author chain B； PDBConstruct 6–122； UniProt 700–816

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id6xa8
Deposition date deposition_date2020-06-04
Structure title titleCrystal Structure of Human Scribble PDZ1:Vangl2 complex
Keywords keywordsCell polarity, Scribble, CYTOSOLIC PROTEIN; CYTOSOLIC PROTEIN
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

6xa8__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

6xa8__assembly_1__model_1 | I(q)

10-2 10-1 105 106 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

6xa8__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）15.68 Å
Rg (electron density)14.60 Å
Total Rg15.66 Å
Atom count1584
Residues109
Excluded volume14084 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 6xa8__assembly_1__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 6xa8__assembly_2__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (5)

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7. Citations (1)