6y1a

Amyloid fibril structure of islet amyloid polypeptide

Method: ELECTRON MICROSCOPY
▼

1. Protein Identity and Related Structures Protein Identity & Related Structures

Islet amyloid polypeptide

OrganismNot specified

UniProt P10997

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 16 AMINO GROUP × 16 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name IAPP_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 1–37; UniProt 34–70 Author chain B; PDBConstruct 1–37; UniProt 34–70 Author chain C; PDBConstruct 1–37; UniProt 34–70 Author chain D; PDBConstruct 1–37; UniProt 34–70 Author chain E; PDBConstruct 1–37; UniProt 34–70 Author chain F; PDBConstruct 1–37; UniProt 34–70 Author chain G; PDBConstruct 1–37; UniProt 34–70 Author chain H; PDBConstruct 1–37; UniProt 34–70 Author chain I; PDBConstruct 1–37; UniProt 34–70 Author chain J; PDBConstruct 1–37; UniProt 34–70 Author chain K; PDBConstruct 1–37; UniProt 34–70 Author chain L; PDBConstruct 1–37; UniProt 34–70 Author chain M; PDBConstruct 1–37; UniProt 34–70 Author chain N; PDBConstruct 1–37; UniProt 34–70 Author chain O; PDBConstruct 1–37; UniProt 34–70 Author chain P; PDBConstruct 1–37; UniProt 34–70

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

▼

2. Structure Basics 2. Structure Basics

Entry ID entry_id6y1a
Deposition date deposition_date2020-02-11
Structure title titleAmyloid fibril structure of islet amyloid polypeptide
Keywords keywordsamylin, iapp, amyloid fibril, diabetes, HORMONE; HORMONE
Experimental Method methodELECTRON MICROSCOPY
▼

3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

6y1a__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

6y1a__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

6y1a__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)20.91 Å
Rg (electron density)19.97 Å
Total Rg20.95 Å
Atom count2960
Residues400
Excluded volume51190 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 6y1a__assembly_1__model_1 hexadecameric (16) Success 4.1.3-1-20251215 (887e7ef) View Download
▶

4. Crystallography and Experiment 4. Crystallography & Experiment

▶

5. Entities and Polymers Entities & Polymers (2)

▶

7. Citations (2)