6z3p

Structure of EV71 in complex with a protective antibody 38-3-11A Fab

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

VP1

OrganismNot specified

UniProt A0A2L1GIK5

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 360 VP2 × 60 (D4QGA2) VP3 × 60 (D4QGA3) VP4 × 60 (Q6YLE3) heavy chain × 60 light chain × 60 SPHINGOSINE × 60 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 6 VP2 × 1 (D4QGA2) VP3 × 1 (D4QGA3) VP4 × 1 (Q6YLE3) heavy chain × 1 light chain × 1 SPHINGOSINE × 1 Consistent with protein count
3 Protein heterocomplex Heteromer Protein 30 VP2 × 5 (D4QGA2) VP3 × 5 (D4QGA3) VP4 × 5 (Q6YLE3) heavy chain × 5 light chain × 5 SPHINGOSINE × 5 Consistent with protein count
4 Protein heterocomplex Heteromer Protein 36 VP2 × 6 (D4QGA2) VP3 × 6 (D4QGA3) VP4 × 6 (Q6YLE3) heavy chain × 6 light chain × 6 SPHINGOSINE × 6 Consistent with protein count
5 Protein heterocomplex Heteromer Protein 6 VP2 × 1 (D4QGA2) VP3 × 1 (D4QGA3) VP4 × 1 (Q6YLE3) heavy chain × 1 light chain × 1 SPHINGOSINE × 1 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name A0A2L1GIK5_HE71
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 1–297; UniProt 566–862

VP2

OrganismNot specified

UniProt D4QGA2

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 360 VP1 × 60 (A0A2L1GIK5) VP3 × 60 (D4QGA3) VP4 × 60 (Q6YLE3) heavy chain × 60 light chain × 60 SPHINGOSINE × 60 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 6 VP1 × 1 (A0A2L1GIK5) VP3 × 1 (D4QGA3) VP4 × 1 (Q6YLE3) heavy chain × 1 light chain × 1 SPHINGOSINE × 1 Consistent with protein count
3 Protein heterocomplex Heteromer Protein 30 VP1 × 5 (A0A2L1GIK5) VP3 × 5 (D4QGA3) VP4 × 5 (Q6YLE3) heavy chain × 5 light chain × 5 SPHINGOSINE × 5 Consistent with protein count
4 Protein heterocomplex Heteromer Protein 36 VP1 × 6 (A0A2L1GIK5) VP3 × 6 (D4QGA3) VP4 × 6 (Q6YLE3) heavy chain × 6 light chain × 6 SPHINGOSINE × 6 Consistent with protein count
5 Protein heterocomplex Heteromer Protein 6 VP1 × 1 (A0A2L1GIK5) VP3 × 1 (D4QGA3) VP4 × 1 (Q6YLE3) heavy chain × 1 light chain × 1 SPHINGOSINE × 1 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name D4QGA2_9ENTO
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B; PDBConstruct 1–254; UniProt 70–323

VP3

OrganismNot specified

UniProt D4QGA3

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 360 VP1 × 60 (A0A2L1GIK5) VP2 × 60 (D4QGA2) VP4 × 60 (Q6YLE3) heavy chain × 60 light chain × 60 SPHINGOSINE × 60 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 6 VP1 × 1 (A0A2L1GIK5) VP2 × 1 (D4QGA2) VP4 × 1 (Q6YLE3) heavy chain × 1 light chain × 1 SPHINGOSINE × 1 Consistent with protein count
3 Protein heterocomplex Heteromer Protein 30 VP1 × 5 (A0A2L1GIK5) VP2 × 5 (D4QGA2) VP4 × 5 (Q6YLE3) heavy chain × 5 light chain × 5 SPHINGOSINE × 5 Consistent with protein count
4 Protein heterocomplex Heteromer Protein 36 VP1 × 6 (A0A2L1GIK5) VP2 × 6 (D4QGA2) VP4 × 6 (Q6YLE3) heavy chain × 6 light chain × 6 SPHINGOSINE × 6 Consistent with protein count
5 Protein heterocomplex Heteromer Protein 6 VP1 × 1 (A0A2L1GIK5) VP2 × 1 (D4QGA2) VP4 × 1 (Q6YLE3) heavy chain × 1 light chain × 1 SPHINGOSINE × 1 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name D4QGA3_9ENTO
Isoform —
PDB entities 3
Chains and sequence ranges Author chain C; PDBConstruct 1–242; UniProt 324–565

VP4

OrganismNot specified

UniProt Q6YLE3

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 360 VP1 × 60 (A0A2L1GIK5) VP2 × 60 (D4QGA2) VP3 × 60 (D4QGA3) heavy chain × 60 light chain × 60 SPHINGOSINE × 60 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 6 VP1 × 1 (A0A2L1GIK5) VP2 × 1 (D4QGA2) VP3 × 1 (D4QGA3) heavy chain × 1 light chain × 1 SPHINGOSINE × 1 Consistent with protein count
3 Protein heterocomplex Heteromer Protein 30 VP1 × 5 (A0A2L1GIK5) VP2 × 5 (D4QGA2) VP3 × 5 (D4QGA3) heavy chain × 5 light chain × 5 SPHINGOSINE × 5 Consistent with protein count
4 Protein heterocomplex Heteromer Protein 36 VP1 × 6 (A0A2L1GIK5) VP2 × 6 (D4QGA2) VP3 × 6 (D4QGA3) heavy chain × 6 light chain × 6 SPHINGOSINE × 6 Consistent with protein count
5 Protein heterocomplex Heteromer Protein 6 VP1 × 1 (A0A2L1GIK5) VP2 × 1 (D4QGA2) VP3 × 1 (D4QGA3) heavy chain × 1 light chain × 1 SPHINGOSINE × 1 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name Q6YLE3_9ENTO
Isoform —
PDB entities 4
Chains and sequence ranges Author chain D; PDBConstruct 1–58; UniProt 12–69

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id6z3p
Deposition date deposition_date2020-05-21
Structure title titleStructure of EV71 in complex with a protective antibody 38-3-11A Fab
Keywords keywordsEV71, antibody 38-3-11A, antibody 38-1-10A, EV71-Fab complex, VIRUS; VIRUS
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

6z3p__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

6z3p__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 1010 1011 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

6z3p__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)0.00 Å
Rg (electron density)138.40 Å
Total Rg138.50 Å
Atom count981360
Residues64200
Excluded volume8835200 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 6z3p__assembly_1__model_1 360-meric (360) Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 6z3p__assembly_2__model_1 hexameric (6) Excluded — —
Exclusion reason: Auxiliary symmetry representation; not a complete or representative biological assembly.
3 1 6z3p__assembly_3__model_1 30-meric (30) Excluded — —
Exclusion reason: Auxiliary symmetry representation; not a complete or representative biological assembly.
4 1 6z3p__assembly_4__model_1 36-meric (36) Excluded — —
Exclusion reason: Auxiliary symmetry representation; not a complete or representative biological assembly.
5 1 6z3p__assembly_5__model_1 hexameric (6) Excluded — —
Exclusion reason: Auxiliary symmetry representation; not a complete or representative biological assembly.
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (7)

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6. Fold Classification (SCOP + CATH) 5 domains

SCOP 2.08 (5 domains)

Domain ID domain_idd6z3pa_
Class classb — All beta proteins
Fold Fold foldb.121 — Nucleoplasmin-like/VP (viral coat and capsid proteins)
Superfamily Superfamily superfamilyb.121.4 — Positive stranded ssRNA viruses
Family Family familyb.121.4.0 — automated matches
Domain ID domain_idd6z3pb_
Class classb — All beta proteins
Fold Fold foldb.121 — Nucleoplasmin-like/VP (viral coat and capsid proteins)
Superfamily Superfamily superfamilyb.121.4 — Positive stranded ssRNA viruses
Family Family familyb.121.4.0 — automated matches
Domain ID domain_idd6z3pc_
Class classb — All beta proteins
Fold Fold foldb.121 — Nucleoplasmin-like/VP (viral coat and capsid proteins)
Superfamily Superfamily superfamilyb.121.4 — Positive stranded ssRNA viruses
Family Family familyb.121.4.1 — Picornaviridae-like VP (VP1, VP2, VP3 and VP4)
Domain ID domain_idd6z3ph_
Class classb — All beta proteins
Fold Fold foldb.1 — Immunoglobulin-like beta-sandwich
Superfamily Superfamily superfamilyb.1.1 — Immunoglobulin
Family Family familyb.1.1.0 — automated matches
Domain ID domain_idd6z3pl_
Class classb — All beta proteins
Fold Fold foldb.1 — Immunoglobulin-like beta-sandwich
Superfamily Superfamily superfamilyb.1.1 — Immunoglobulin
Family Family familyb.1.1.1 — V set domains (antibody variable domain-like)
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7. Citations (1)