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7knw

Crystal structure of SND1 in complex with C-26-A2

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Staphylococcal nuclease domain-containing protein 1

Homo sapiens

UniProt Q7KZF4

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein monomer Monomer Protein 1 GLYCEROL × 1 5-chloro-2-methoxy-N-([1,2,4]triazolo[1,5-a]pyridin-8-yl)benzene-1-sulfonamide × 1 water × 1 Consistent with protein count
2 Protein monomer Monomer Protein 1 GLYCEROL × 1 5-chloro-2-methoxy-N-([1,2,4]triazolo[1,5-a]pyridin-8-yl)benzene-1-sulfonamide × 1 water × 1 Consistent with protein count
3 Protein monomer Monomer Protein 1 5-chloro-2-methoxy-N-([1,2,4]triazolo[1,5-a]pyridin-8-yl)benzene-1-sulfonamide × 1 water × 1 Consistent with protein count
4 Protein monomer Monomer Protein 1 GLYCEROL × 1 5-chloro-2-methoxy-N-([1,2,4]triazolo[1,5-a]pyridin-8-yl)benzene-1-sulfonamide × 1 water × 1 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
2e6n 3bdl 7knw 7knw 7knw 7knw 7knx 7knx 7knx 7knx

10 assemblies

Homodimer
2hqe 2hqx 2o4x 3bdl

4 assemblies

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
3omc 3omc 3omg 3omg 4qmg 4qmg 4qmg 4qmg 4qmg 5m9o

10 assemblies

View Construct and Data Evidence
UniProt name SND1_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 21–324； UniProt 16–330 Author chain B； PDBConstruct 21–324； UniProt 16–330 Author chain C； PDBConstruct 21–324； UniProt 16–330 Author chain D； PDBConstruct 21–324； UniProt 16–330

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id7knw
Deposition date deposition_date2020-11-06
Structure title titleCrystal structure of SND1 in complex with C-26-A2
Keywords keywordsInhibitor, Endonuclease, HYDROLASE, HYDROLASE-INHIBITOR complex; HYDROLASE/INHIBITOR
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

7knw__assembly_4__model_1

Assembly 4 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

7knw__assembly_4__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

7knw__assembly_4__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）22.71 Å
Rg (electron density)21.51 Å
Total Rg22.28 Å
Atom count2389
Residues296
Excluded volume42364 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 7knw__assembly_1__model_1 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 7knw__assembly_2__model_1 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
3 1 7knw__assembly_3__model_1 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
4 1 7knw__assembly_4__model_1 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (4)

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7. Citations (1)