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7kqn

Ternary complex of TERT (telomerase reverse transcriptase) with RNA template, DNA primer, an incoming dGTP and a downstream hybrid duplex

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Telomerase reverse transcriptase

Tribolium castaneum

UniProt Q0QHL8

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Other combination Monomer Protein 1 DNA 2 RNA 1 ;RNA (5'-R(*CP*AP*AP*AP*GP*AP*AP*AP*UP*CP*CP*AP*GP*GP*UP*GP*CP*A)-3') ; × 1 ;DNA (5'-D(*GP*CP*AP*CP*CP*TP*G)-3') ; × 1 ;DNA (5'-D(*TP*TP*CP*TP*TP*TP*G)-3') ; × 1 1,2-ETHANEDIOL × 10 2-(N-MORPHOLINO)-ETHANESULFONIC ACID × 2 DI(HYDROXYETHYL)ETHER × 1 CALCIUM ION × 1 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE × 1 water × 4 Consistent with all polymers
2 Other combination Monomer Protein 1 DNA 2 RNA 1 ;RNA (5'-R(*CP*AP*AP*AP*GP*AP*AP*AP*UP*CP*CP*AP*GP*GP*UP*GP*CP*A)-3') ; × 1 ;DNA (5'-D(*GP*CP*AP*CP*CP*TP*G)-3') ; × 1 ;DNA (5'-D(*TP*TP*CP*TP*TP*TP*G)-3') ; × 1 1,2-ETHANEDIOL × 11 DI(HYDROXYETHYL)ETHER × 1 CALCIUM ION × 1 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE × 1 water × 4 Consistent with all polymers

Other States of the Same Protein in the Database

Monomer
3du5 3du5 3du6 3du6 5cqg 5cqg

6 assemblies

Homodimer
5cqg

1 assemblies

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
3kyl 6e53 6uso 6usp 6usq 6usr 7kqm 7kqn 7kqn

9 assemblies

View Construct and Data Evidence
UniProt name Q0QHL8_TRICA
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–596； UniProt 1–596 Author chain D； PDBConstruct 1–596； UniProt 1–596

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id7kqn
Deposition date deposition_date2020-11-17
Structure title titleTernary complex of TERT (telomerase reverse transcriptase) with RNA template, DNA primer, an incoming dGTP and a downstream hybrid duplex
Keywords keywords;RAP, Repeat Addition Processivity, DNA hairpin, RNA template, telomere, TBE, Template-Boundary Element, TRANSFERASE, TRANSFERASE-RNA-DNA complex ;; TRANSFERASE/RNA/DNA
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

7kqn__assembly_2__model_1

Assembly 2 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

7kqn__assembly_2__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

7kqn__assembly_2__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）28.92 Å
Rg (electron density)28.29 Å
Total Rg29.03 Å
Atom count5677
Residues628
Excluded volume100330 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 7kqn__assembly_1__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 7kqn__assembly_2__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (10)

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7. Citations (2)