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7nld

Structure of human Programmed cell death 1 ligand 1 (PD-L1) with low molecular mass inhibitor

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Programmed cell death 1 ligand 1

Homo sapiens

UniProt Q9NZQ7

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 2 N-(2-((2'-chloro-3'-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-3-methoxy-[1,1'-biphenyl]-4-yl)(methyl)amino)ethyl)methanesulfonamide × 1 water × 2 Consistent with protein count
2 Protein homooligomer Homooligomer Protein 2 N-(2-((2'-chloro-3'-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-3-methoxy-[1,1'-biphenyl]-4-yl)(methyl)amino)ethyl)methanesulfonamide × 1 water × 2 Consistent with protein count
3 Protein homooligomer Homooligomer Protein 2 N-(2-((2'-chloro-3'-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-3-methoxy-[1,1'-biphenyl]-4-yl)(methyl)amino)ethyl)methanesulfonamide × 1 water × 2 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
3bis 3bis 5c3t 5xj4 6l8r 7dcv 9ksb 9ksb 9ksb 9ksb 9ksb 9ksb

18 assemblies; showing the first 12

Homodimer
3fn3 4z18 5j89 5j89 5j8o 5jdr 5n2f 5niu 5niu 6nm7 6nm8 6noj

41 assemblies; showing the first 12

Homotetramer
5n2d 9ijt

2 assemblies

Other homooligomers
7vun

1 assemblies

Heteromeric or nucleic-acid complex
13fl 3bik 3sbw 4zqk 5ggt 5grj 5ius 5ius 5jds 5o45 5o4y 5o4y

63 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name PD1L1_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–117； UniProt 18–134 Author chain B； PDBConstruct 1–117； UniProt 18–134 Author chain C； PDBConstruct 1–117； UniProt 18–134 Author chain D； PDBConstruct 1–117； UniProt 18–134 Author chain E； PDBConstruct 1–117； UniProt 18–134 Author chain F； PDBConstruct 1–117； UniProt 18–134

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id7nld
Deposition date deposition_date2021-02-22
Structure title titleStructure of human Programmed cell death 1 ligand 1 (PD-L1) with low molecular mass inhibitor
Keywords keywordsPD-L1, cancer, inhibitor, IMMUNE SYSTEM; IMMUNE SYSTEM
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

7nld__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

7nld__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

7nld__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）19.21 Å
Rg (electron density)18.33 Å
Total Rg19.20 Å
Atom count1772
Residues230
Excluded volume31556 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 7nld__assembly_1__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 7nld__assembly_2__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
3 1 7nld__assembly_3__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

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7. Citations (1)