7po6

Xist (m6A)UCG tetraloop RNA bound to the YTH domain of YTHDC1

Method: X-RAY DIFFRACTION
▼

1. Protein Identity and Related Structures Protein Identity & Related Structures

Isoform 2 of YTH domain-containing protein 1

Homo sapiens

UniProt Q96MU7

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Monomer Protein 1 RNA 1 ;RNA (5'-R(*(6MZ)P*UP*C)-3') ; × 1 GUANOSINE-5'-TRIPHOSPHATE × 1 1,2-ETHANEDIOL × 4 SULFATE ION × 3 water × 2 Consistent with all polymers
2 Protein–RNA Monomer Protein 1 RNA 1 ;RNA (5'-R(*(6MZ)P*UP*C)-3') ; × 1 1,2-ETHANEDIOL × 2 SULFATE ION × 1 water × 2 Consistent with all polymers
3 Protein–RNA Monomer Protein 1 RNA 1 ;RNA (5'-R(*(6MZ)P*UP*C)-3') ; × 1 1,2-ETHANEDIOL × 1 SULFATE ION × 3 SODIUM ION × 1 water × 2 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name YTDC1_HUMAN
Isoform Q96MU7-2
PDB entities 2
Chains and sequence ranges Author chain A; PDBConstruct 5–169; UniProt 327–491 Author chain B; PDBConstruct 5–169; UniProt 327–491 Author chain C; PDBConstruct 5–169; UniProt 327–491

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

▼

2. Structure Basics 2. Structure Basics

Entry ID entry_id7po6
Deposition date deposition_date2021-09-08
Structure title titleXist (m6A)UCG tetraloop RNA bound to the YTH domain of YTHDC1
Keywords keywordsm6A, YTHDC1, XIST, Complex, RNA BINDING PROTEIN; RNA BINDING PROTEIN
Experimental Method methodX-RAY DIFFRACTION
▼

3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

7po6__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

7po6__assembly_1__model_1 | I(q)

10-2 10-1 105 106 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

7po6__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)16.55 Å
Rg (electron density)15.19 Å
Total Rg16.35 Å
Atom count2787
Residues168
Excluded volume24991 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 7po6__assembly_1__model_1 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 7po6__assembly_2__model_1 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
3 1 7po6__assembly_3__model_1 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
▶

4. Crystallography and Experiment 4. Crystallography & Experiment

▶

5. Entities and Polymers Entities & Polymers (7)

▶

7. Citations (1)