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7ti5

Adeno-associated virus Go.1 in Complex With Its Cellular Receptor AAVR at 2.4 Angstroms Resolution, AAVGo.1 AAVR

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Dyslexia-associated protein KIAA0319-like protein

Homo sapiens

UniProt Q8IZA0

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 120 Capsid protein × 60 （Q5XXZ6） Consistent with protein count
2 Protein heterocomplex Heteromer Protein 2 Capsid protein × 1 （Q5XXZ6） Consistent with protein count
3 Protein heterocomplex Heteromer Protein 10 Capsid protein × 5 （Q5XXZ6） Consistent with protein count
4 Protein heterocomplex Heteromer Protein 12 Capsid protein × 6 （Q5XXZ6） Consistent with protein count
5 Protein heterocomplex Heteromer Protein 2 Capsid protein × 1 （Q5XXZ6） Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
6ihb 6ihb 6ihb 6ihb 6ihb 6jcq 6jcq 6jcq 6jcq 6jcq 6jcs 6jcs

40 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name K319L_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain Z； PDBConstruct 4–290； UniProt 311–597

Capsid protein

Adeno-associated virus

UniProt Q5XXZ6

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 120 Dyslexia-associated protein KIAA0319-like protein × 60 （Q8IZA0） Consistent with protein count
2 Protein heterocomplex Heteromer Protein 2 Dyslexia-associated protein KIAA0319-like protein × 1 （Q8IZA0） Consistent with protein count
3 Protein heterocomplex Heteromer Protein 10 Dyslexia-associated protein KIAA0319-like protein × 5 （Q8IZA0） Consistent with protein count
4 Protein heterocomplex Heteromer Protein 12 Dyslexia-associated protein KIAA0319-like protein × 6 （Q8IZA0） Consistent with protein count
5 Protein heterocomplex Heteromer Protein 2 Dyslexia-associated protein KIAA0319-like protein × 1 （Q8IZA0） Consistent with protein count

Other States of the Same Protein in the Database

Monomer
7ti4 7ti4

2 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers
7ti4 7ti4 7ti4

3 assemblies

Heteromeric or nucleic-acid complex
7ti5 7ti5 7ti5 7ti5 7ti5

5 assemblies

View Construct and Data Evidence
UniProt name Q5XXZ6_9VIRU
Isoform —
PDB entities 2
Chains and sequence ranges Author chain A； PDBConstruct 1–726； UniProt 1–726

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id7ti5
Deposition date deposition_date2022-01-12
Structure title titleAdeno-associated virus Go.1 in Complex With Its Cellular Receptor AAVR at 2.4 Angstroms Resolution, AAVGo.1 AAVR
Keywords keywords;AAVGo.1, AAV, AAV-Go, AAVR, adeno-associated virus, PKD domain, parvovirus, gene therapy, receptor, adeno-associated virus receptor, PKD1, PKD, VIRUS LIKE PARTICLE ;; VIRUS LIKE PARTICLE
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

7ti5__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

7ti5__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 1010 1011 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

7ti5__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）0.00 Å
Rg (electron density)112.70 Å
Total Rg112.90 Å
Atom count289380
Residues36360
Excluded volume5074700 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 7ti5__assembly_1__model_1 120-meric （120） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 7ti5__assembly_2__model_1 dimeric （2） Excluded — —
Exclusion reason： Auxiliary symmetry representation; not a complete or representative biological assembly.
3 1 7ti5__assembly_3__model_1 decameric （10） Excluded — —
Exclusion reason： Auxiliary symmetry representation; not a complete or representative biological assembly.
4 1 7ti5__assembly_4__model_1 dodecameric （12） Excluded — —
Exclusion reason： Auxiliary symmetry representation; not a complete or representative biological assembly.
5 1 7ti5__assembly_5__model_1 dimeric （2） Excluded — —
Exclusion reason： Auxiliary symmetry representation; not a complete or representative biological assembly.
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (2)

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7. Citations (1)