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7vqq

Cryo-EM structure of amyloid fibril formed by FUS low complexity domain

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

fusion protein of mCerulean and FUS LCD

Homo sapiens

UniProt P35637

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 3 No other associated polymer Consistent with protein count

Other States of the Same Protein in the Database

Monomer
2la6 2lcw 5xrr 5xsg 6kj1 6kj2 6kj3 6kj4

8 assemblies

Homodimer
5xrr

1 assemblies

Homotetramer

None

Other homooligomers
5w3n 6bzp 6xfm 7vqq

4 assemblies

Heteromeric or nucleic-acid complex
4fdd 5yvg 5yvg 5yvh 5yvi 6g99 6gbm 6snj 7cyl

9 assemblies

View Construct and Data Evidence
UniProt name FUS_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 271–483； UniProt 2–214 Author chain B； PDBConstruct 271–483； UniProt 2–214 Author chain C； PDBConstruct 271–483； UniProt 2–214

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id7vqq
Deposition date deposition_date2021-10-20
Structure title titleCryo-EM structure of amyloid fibril formed by FUS low complexity domain
Keywords keywordsamyloid fibril, PROTEIN FIBRIL; PROTEIN FIBRIL
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

7vqq__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

7vqq__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

7vqq__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）22.26 Å
Rg (electron density)21.91 Å
Total Rg22.56 Å
Atom count1950
Residues273
Excluded volume32401 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 7vqq__assembly_1__model_1 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (1)

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7. Citations (1)