Homo sapiens
| Assembly | 物理组成 | 蛋白状态 | 分子拷贝数 | 共同组分 | 数据核对 |
|---|---|---|---|---|---|
| 1 | 蛋白同源多聚体 | 同源多聚体 | 蛋白 6 | PHOSPHATIDYLETHANOLAMINE × 6 CHOLESTEROL HEMISUCCINATE × 6 | 与蛋白数一致 |
| UniProt名称 | CXA1_HUMAN |
| Isoform | — |
| PDB实体 | 1 |
| 链与序列区间 | 作者链 A； PDB构建体 1–257； UniProt 1–257 作者链 B； PDB构建体 1–257； UniProt 1–257 作者链 C； PDB构建体 1–257； UniProt 1–257 作者链 D； PDB构建体 1–257； UniProt 1–257 作者链 E； PDB构建体 1–257； UniProt 1–257 作者链 F； PDB构建体 1–257； UniProt 1–257 |
页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。
| 条目编号 entry_id | 7xqg |
| 沉积日期 deposition_date | 2022-05-07 |
| 结构标题 title | Hemichannel-focused structure of C-terminal truncated connexin43/Cx43/GJA1 gap junction intercellular channel in POPE nanodiscs (GCN conformation) |
| 关键词 keywords | Cx43, Connexin, Gap junction channel, Gating mechanism, Membrane protein; MEMBRANE PROTEIN |
| 实验方法 method | ELECTRON MICROSCOPY |
页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 35.78 Å |
| Rg（电子密度） | 34.19 Å |
| 总 Rg | 35.04 Å |
| 原子数 | 10206 |
| 残基数 | 1206 |
| 排除体积 | 187900 ų |
| 最大 q | 0.500 Å⁻¹ |
| 结构域编号 domain_id | 7xqgA01 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 20 — Up-down Bundle |
| 拓扑 Topology topology | 1440 — de novo design (two linked rop proteins) |
| 同源超家族 H-superfamily homologous superfamily | 80 — Gap junction channel protein cysteine-rich domain |
| 结构域编号 domain_id | 7xqgB01 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 20 — Up-down Bundle |
| 拓扑 Topology topology | 1440 — de novo design (two linked rop proteins) |
| 同源超家族 H-superfamily homologous superfamily | 80 — Gap junction channel protein cysteine-rich domain |
| 结构域编号 domain_id | 7xqgC01 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 20 — Up-down Bundle |
| 拓扑 Topology topology | 1440 — de novo design (two linked rop proteins) |
| 同源超家族 H-superfamily homologous superfamily | 80 — Gap junction channel protein cysteine-rich domain |
| 结构域编号 domain_id | 7xqgD01 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 20 — Up-down Bundle |
| 拓扑 Topology topology | 1440 — de novo design (two linked rop proteins) |
| 同源超家族 H-superfamily homologous superfamily | 80 — Gap junction channel protein cysteine-rich domain |
| 结构域编号 domain_id | 7xqgE01 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 20 — Up-down Bundle |
| 拓扑 Topology topology | 1440 — de novo design (two linked rop proteins) |
| 同源超家族 H-superfamily homologous superfamily | 80 — Gap junction channel protein cysteine-rich domain |
| 结构域编号 domain_id | 7xqgF01 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 20 — Up-down Bundle |
| 拓扑 Topology topology | 1440 — de novo design (two linked rop proteins) |
| 同源超家族 H-superfamily homologous superfamily | 80 — Gap junction channel protein cysteine-rich domain |