7xur

The cryo-EM structure of human mini-SNAPc in complex with hU6-1 PSE

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

snRNA-activating protein complex subunit 4

Homo sapiens

UniProt Q5SXM2

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Heteromer Protein 3 DNA 2 snRNA-activating protein complex subunit 3 × 1 (Q92966) snRNA-activating protein complex subunit 1 × 1 (Q16533) DNA (35-MER) × 1 DNA (35-MER) × 1 ZINC ION × 2 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SNPC4_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 18–522; UniProt 1–505

snRNA-activating protein complex subunit 3

Homo sapiens

UniProt Q92966

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Heteromer Protein 3 DNA 2 snRNA-activating protein complex subunit 4 × 1 (Q5SXM2) snRNA-activating protein complex subunit 1 × 1 (Q16533) DNA (35-MER) × 1 DNA (35-MER) × 1 ZINC ION × 2 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SNPC3_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B; PDBConstruct 1–411; UniProt 1–411

snRNA-activating protein complex subunit 1

Homo sapiens

UniProt Q16533

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Heteromer Protein 3 DNA 2 snRNA-activating protein complex subunit 4 × 1 (Q5SXM2) snRNA-activating protein complex subunit 3 × 1 (Q92966) DNA (35-MER) × 1 DNA (35-MER) × 1 ZINC ION × 2 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SNPC1_HUMAN
Isoform —
PDB entities 3
Chains and sequence ranges Author chain C; PDBConstruct 15–282; UniProt 1–268

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id7xur
Deposition date deposition_date2022-05-19
Structure title titleThe cryo-EM structure of human mini-SNAPc in complex with hU6-1 PSE
Keywords keywordssnRNA, Transcription factor, Complex, PSE., TRANSCRIPTION, TRANSCRIPTION-DNA complex; TRANSCRIPTION/DNA
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

7xur__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

7xur__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

7xur__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)35.07 Å
Rg (electron density)34.77 Å
Total Rg35.12 Å
Atom count7749
Residues862
Excluded volume134530 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 7xur__assembly_1__model_1 pentameric (5) Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (6)

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7. Citations (1)