8agc

Structure of yeast oligosaccharylransferase complex with lipid-linked oligosaccharide and non-acceptor peptide bound

Method: ELECTRON MICROSCOPY

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1. 蛋白身份与相关结构 Protein Identity & Related Structures

Dolichyl-diphosphooligosaccharide--protein glycotransferase

Saccharomyces cerevisiae

当前结构中的状态

Assembly	物理组成	蛋白状态	分子拷贝数	共同组分	数据核对
1	其他组合	异源复合物	蛋白 9 其他聚合物 4	OST4 isoform 1 × 1 （A0A8H8UM72） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST5 × 1 （Q92316） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2 × 1 （A0A8H4BUV6） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 × 1 （A0A6A5PXA1） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 × 1 （A0A6V8S2Y6） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1 × 1 （A0A8H8ULL1） OST3 isoform 1 × 1 （A0A6A5Q3S9） PEPTIDE × 1 ;alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 1 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 2 ;alpha-D-glucopyranose-(1-2)-alpha-D-glucopyranose-(1-3)-alpha-D-glucopyranose-(1-3)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose ; × 1 phosphono [(3~{R},6~{E},10~{E})-3,7,11,15-tetramethylhexadeca-6,10,14-trienyl] hydrogen phosphate × 1 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 4 PHOSPHATIDYLETHANOLAMINE × 2 MANGANESE (II) ION × 1 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 2-[3,6-bis(dimethylamino)xanthen-9-yl]-5-methanoyl-benzoate × 1	与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据

UniProt名称	A0A6A5Q0M3_YEASX
Isoform	—
PDB实体	1
链与序列区间	作者链 A； PDB构建体 1–718； UniProt 1–718

OST4 isoform 1

Saccharomyces cerevisiae

UniProt A0A8H8UM72

当前结构中的状态

Assembly	物理组成	蛋白状态	分子拷贝数	共同组分	数据核对
1	其他组合	异源复合物	蛋白 9 其他聚合物 4	Dolichyl-diphosphooligosaccharide--protein glycotransferase × 1 （A0A6A5Q0M3） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST5 × 1 （Q92316） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2 × 1 （A0A8H4BUV6） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 × 1 （A0A6A5PXA1） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 × 1 （A0A6V8S2Y6） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1 × 1 （A0A8H8ULL1） OST3 isoform 1 × 1 （A0A6A5Q3S9） PEPTIDE × 1 ;alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 1 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 2 ;alpha-D-glucopyranose-(1-2)-alpha-D-glucopyranose-(1-3)-alpha-D-glucopyranose-(1-3)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose ; × 1 phosphono [(3~{R},6~{E},10~{E})-3,7,11,15-tetramethylhexadeca-6,10,14-trienyl] hydrogen phosphate × 1 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 4 PHOSPHATIDYLETHANOLAMINE × 2 MANGANESE (II) ION × 1 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 2-[3,6-bis(dimethylamino)xanthen-9-yl]-5-methanoyl-benzoate × 1	与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据

UniProt名称	A0A8H8UM72_YEASX
Isoform	—
PDB实体	2
链与序列区间	作者链 B； PDB构建体 1–36； UniProt 1–36

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST5

Saccharomyces cerevisiae

UniProt Q92316

当前结构中的状态

Assembly	物理组成	蛋白状态	分子拷贝数	共同组分	数据核对
1	其他组合	异源复合物	蛋白 9 其他聚合物 4	Dolichyl-diphosphooligosaccharide--protein glycotransferase × 1 （A0A6A5Q0M3） OST4 isoform 1 × 1 （A0A8H8UM72） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2 × 1 （A0A8H4BUV6） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 × 1 （A0A6A5PXA1） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 × 1 （A0A6V8S2Y6） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1 × 1 （A0A8H8ULL1） OST3 isoform 1 × 1 （A0A6A5Q3S9） PEPTIDE × 1 ;alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 1 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 2 ;alpha-D-glucopyranose-(1-2)-alpha-D-glucopyranose-(1-3)-alpha-D-glucopyranose-(1-3)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose ; × 1 phosphono [(3~{R},6~{E},10~{E})-3,7,11,15-tetramethylhexadeca-6,10,14-trienyl] hydrogen phosphate × 1 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 4 PHOSPHATIDYLETHANOLAMINE × 2 MANGANESE (II) ION × 1 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 2-[3,6-bis(dimethylamino)xanthen-9-yl]-5-methanoyl-benzoate × 1	与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据

UniProt名称	OST5_YEAST
Isoform	—
PDB实体	3
链与序列区间	作者链 C； PDB构建体 1–86； UniProt 1–86

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2

Saccharomyces cerevisiae

UniProt A0A8H4BUV6

当前结构中的状态

Assembly	物理组成	蛋白状态	分子拷贝数	共同组分	数据核对
1	其他组合	异源复合物	蛋白 9 其他聚合物 4	Dolichyl-diphosphooligosaccharide--protein glycotransferase × 1 （A0A6A5Q0M3） OST4 isoform 1 × 1 （A0A8H8UM72） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST5 × 1 （Q92316） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 × 1 （A0A6A5PXA1） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 × 1 （A0A6V8S2Y6） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1 × 1 （A0A8H8ULL1） OST3 isoform 1 × 1 （A0A6A5Q3S9） PEPTIDE × 1 ;alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 1 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 2 ;alpha-D-glucopyranose-(1-2)-alpha-D-glucopyranose-(1-3)-alpha-D-glucopyranose-(1-3)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose ; × 1 phosphono [(3~{R},6~{E},10~{E})-3,7,11,15-tetramethylhexadeca-6,10,14-trienyl] hydrogen phosphate × 1 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 4 PHOSPHATIDYLETHANOLAMINE × 2 MANGANESE (II) ION × 1 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 2-[3,6-bis(dimethylamino)xanthen-9-yl]-5-methanoyl-benzoate × 1	与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据

UniProt名称	A0A8H4BUV6_YEASX
Isoform	—
PDB实体	4
链与序列区间	作者链 D； PDB构建体 1–130； UniProt 1–130

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

Saccharomyces cerevisiae

UniProt A0A6A5PXA1

当前结构中的状态

Assembly	物理组成	蛋白状态	分子拷贝数	共同组分	数据核对
1	其他组合	异源复合物	蛋白 9 其他聚合物 4	Dolichyl-diphosphooligosaccharide--protein glycotransferase × 1 （A0A6A5Q0M3） OST4 isoform 1 × 1 （A0A8H8UM72） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST5 × 1 （Q92316） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2 × 1 （A0A8H4BUV6） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 × 1 （A0A6V8S2Y6） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1 × 1 （A0A8H8ULL1） OST3 isoform 1 × 1 （A0A6A5Q3S9） PEPTIDE × 1 ;alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 1 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 2 ;alpha-D-glucopyranose-(1-2)-alpha-D-glucopyranose-(1-3)-alpha-D-glucopyranose-(1-3)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose ; × 1 phosphono [(3~{R},6~{E},10~{E})-3,7,11,15-tetramethylhexadeca-6,10,14-trienyl] hydrogen phosphate × 1 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 4 PHOSPHATIDYLETHANOLAMINE × 2 MANGANESE (II) ION × 1 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 2-[3,6-bis(dimethylamino)xanthen-9-yl]-5-methanoyl-benzoate × 1	与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据

UniProt名称	A0A6A5PXA1_YEASX
Isoform	—
PDB实体	5
链与序列区间	作者链 E； PDB构建体 1–476； UniProt 1–476

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

Saccharomyces cerevisiae

UniProt A0A6V8S2Y6

当前结构中的状态

Assembly	物理组成	蛋白状态	分子拷贝数	共同组分	数据核对
1	其他组合	异源复合物	蛋白 9 其他聚合物 4	Dolichyl-diphosphooligosaccharide--protein glycotransferase × 1 （A0A6A5Q0M3） OST4 isoform 1 × 1 （A0A8H8UM72） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST5 × 1 （Q92316） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2 × 1 （A0A8H4BUV6） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 × 1 （A0A6A5PXA1） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1 × 1 （A0A8H8ULL1） OST3 isoform 1 × 1 （A0A6A5Q3S9） PEPTIDE × 1 ;alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 1 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 2 ;alpha-D-glucopyranose-(1-2)-alpha-D-glucopyranose-(1-3)-alpha-D-glucopyranose-(1-3)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose ; × 1 phosphono [(3~{R},6~{E},10~{E})-3,7,11,15-tetramethylhexadeca-6,10,14-trienyl] hydrogen phosphate × 1 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 4 PHOSPHATIDYLETHANOLAMINE × 2 MANGANESE (II) ION × 1 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 2-[3,6-bis(dimethylamino)xanthen-9-yl]-5-methanoyl-benzoate × 1	与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据

UniProt名称	A0A6V8S2Y6_YEASX
Isoform	—
PDB实体	6
链与序列区间	作者链 F； PDB构建体 1–283； UniProt 1–283

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1

Saccharomyces cerevisiae

UniProt A0A8H8ULL1

当前结构中的状态

Assembly	物理组成	蛋白状态	分子拷贝数	共同组分	数据核对
1	其他组合	异源复合物	蛋白 9 其他聚合物 4	Dolichyl-diphosphooligosaccharide--protein glycotransferase × 1 （A0A6A5Q0M3） OST4 isoform 1 × 1 （A0A8H8UM72） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST5 × 1 （Q92316） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2 × 1 （A0A8H4BUV6） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 × 1 （A0A6A5PXA1） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 × 1 （A0A6V8S2Y6） OST3 isoform 1 × 1 （A0A6A5Q3S9） PEPTIDE × 1 ;alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 1 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 2 ;alpha-D-glucopyranose-(1-2)-alpha-D-glucopyranose-(1-3)-alpha-D-glucopyranose-(1-3)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose ; × 1 phosphono [(3~{R},6~{E},10~{E})-3,7,11,15-tetramethylhexadeca-6,10,14-trienyl] hydrogen phosphate × 1 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 4 PHOSPHATIDYLETHANOLAMINE × 2 MANGANESE (II) ION × 1 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 2-[3,6-bis(dimethylamino)xanthen-9-yl]-5-methanoyl-benzoate × 1	与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据

UniProt名称	A0A8H8ULL1_YEASX
Isoform	—
PDB实体	7
链与序列区间	作者链 G； PDB构建体 1–430； UniProt 1–430

OST3 isoform 1

Saccharomyces cerevisiae

UniProt A0A6A5Q3S9

当前结构中的状态

Assembly	物理组成	蛋白状态	分子拷贝数	共同组分	数据核对
1	其他组合	异源复合物	蛋白 9 其他聚合物 4	Dolichyl-diphosphooligosaccharide--protein glycotransferase × 1 （A0A6A5Q0M3） OST4 isoform 1 × 1 （A0A8H8UM72） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST5 × 1 （Q92316） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2 × 1 （A0A8H4BUV6） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 × 1 （A0A6A5PXA1） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 × 1 （A0A6V8S2Y6） Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1 × 1 （A0A8H8ULL1） PEPTIDE × 1 ;alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ; × 1 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 2 ;alpha-D-glucopyranose-(1-2)-alpha-D-glucopyranose-(1-3)-alpha-D-glucopyranose-(1-3)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose ; × 1 phosphono [(3~{R},6~{E},10~{E})-3,7,11,15-tetramethylhexadeca-6,10,14-trienyl] hydrogen phosphate × 1 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 4 PHOSPHATIDYLETHANOLAMINE × 2 MANGANESE (II) ION × 1 2-acetamido-2-deoxy-beta-D-glucopyranose × 2 2-[3,6-bis(dimethylamino)xanthen-9-yl]-5-methanoyl-benzoate × 1	与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据

UniProt名称	A0A6A5Q3S9_YEASX
Isoform	—
PDB实体	8
链与序列区间	作者链 H； PDB构建体 1–350； UniProt 1–350

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。

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2. 结构基本信息 2. Structure Basics

条目编号 entry_id	8agc
沉积日期 deposition_date	2022-07-19
结构标题 title	Structure of yeast oligosaccharylransferase complex with lipid-linked oligosaccharide and non-acceptor peptide bound
关键词 keywords	N-glycosylation OST complex, TRANSFERASE; TRANSFERASE
实验方法 method	ELECTRON MICROSCOPY

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3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

8agc__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

8agc__assembly_1__model_1 | I(q)

100 个绘图点；横轴和纵轴均采用对数尺度。

8agc__assembly_1__model_1 | P(r) · Pending

P(r) 将按相同 assembly/model 分别计算和展示。

Rg（Guinier）	46.17 Å
Rg（电子密度）	45.99 Å
总 Rg	46.23 Å
原子数	17764
残基数	2151
排除体积	321810 Å³
最大 q	0.500 Å⁻¹

Assembly	Model	结构单元	聚集说明	状态	CRYSOL	操作
1	1	`8agc__assembly_1__model_1`	nonameric （9）	成功	4.1.3-1-20251215 (887e7ef)	查看下载

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4. 晶体学与实验 4. Crystallography & Experiment

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5. 实体与聚合物信息 Entities & Polymers (18)

实体 1 Entity 1 polymer

描述 description	Dolichyl-diphosphooligosaccharide--protein glycotransferase
分子量 formula_weight	81604.5 kDa
EC 编号 ec_number	2.4.99.18
来源方法 src_method	man
拷贝数 entity_count	1

聚合物 Polymer

聚合物类型 type	polypeptide(L)
链编号 strand_id	A
原子数 atom_count	17764

MGSDRSCVLSVFQTILKLVIFVAIFGAAISSRLFAVIKFESIIHEFDPWFNYRATKYLVNNSFYKFLNWFDDRTWYPLGRVTGGTLYPGLMTTSAFIWHALRNWLGLPIDIRNVCVLFAPLFSGVTAWATYEFTKEIKDASAGLLAAGFIAIVPGYISRSVAGSYDNEAIAITLLMVTFMFWIKAQKTGSIMHATCAALFYFYMVSAWGGYVFITNLIPLHVFLLILMGRYSSKLYSAYTTWYAIGTVASMQIPFVGFLPIRSNDHMAALGVFGLIQIVAFGDFVKGQISTAKFKVIMMVSLFLILVLGVVGLSALTYMGLIAPWTGRFYSLWDTNYAKIHIPIIASVSEHQPVSWPAFFFDTHFLIWLFPAGVFLLFLDLKDEHVFVIAYSVLCSYFAGVMVRLMLTLTPVICVSAAVALSKIFDIYLDFKTSDRKYAIKPAALLAKLIVSGSFIFYLYLFVFHSTWVTRTAYSSPSVVLPSQTPDGKLALIDDFREAYYWLRMNSDEDSKVAAWWDYGYQIGGMADRTTLVDNNTWNNTHIAIVGKAMASPEEKSYEILKEHDVDYVLVIFGGLIGFGGDDINKFLWMIRISEGIWPEEIKERDFYTAEGEYRVDARASETMRNSLLYKMSYKDFPQLFNGGQATDRVRQQMITPLDVPPLDYFDEVFTSENWMVRIYQLKKDDAQGRTLRDVGELTRSSTKTRRSIKRPELGLRV

来源 Source

来源生物 organism	Saccharomyces cerevisiae
通用名 common_name	;baker's yeast ;
NCBI 分类编号 ncbi_taxonomy_id	4932
宿主生物 host_organism	Saccharomyces cerevisiae

实体 2 Entity 2 polymer

描述 description	OST4 isoform 1
分子量 formula_weight	6871.8 kDa
来源方法 src_method	man
拷贝数 entity_count	1

聚合物 Polymer

聚合物类型 type	polypeptide(L)
链编号 strand_id	B

MISDEQLNSLAITFGIVMMTLIVIYHAVDSTMSPKNRTLQVDGGSGGSLEVLFQGPTETSQVAPA

来源 Source

来源生物 organism	Saccharomyces cerevisiae
通用名 common_name	;baker's yeast ;
NCBI 分类编号 ncbi_taxonomy_id	4932
宿主生物 host_organism	Saccharomyces cerevisiae

实体 3 Entity 3 polymer

描述 description	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST5
分子量 formula_weight	9525.1 kDa
来源方法 src_method	man
拷贝数 entity_count	1

聚合物 Polymer

聚合物类型 type	polypeptide(L)
链编号 strand_id	C

MTYEQLYKEFHSSKSFQPFIHLDTQPKFAICGLIVTLAVLSSALFAVGSKSSYIKKLFFYTILSVIGSLFAGLTTVFASNSFGVYV

来源 Source

来源生物 organism	Saccharomyces cerevisiae
通用名 common_name	;baker's yeast ;
NCBI 分类编号 ncbi_taxonomy_id	4932
宿主生物 host_organism	Saccharomyces cerevisiae

实体 4 Entity 4 polymer

描述 description	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2
分子量 formula_weight	14712.5 kDa
来源方法 src_method	man
拷贝数 entity_count	1

聚合物 Polymer

聚合物类型 type	polypeptide(L)
链编号 strand_id	D

MAKAPKANTPKVTSTSSAVLTDFQETFKTSKRAYFAQIEKYPKLKLIDTFCFFLVLLGVIQCTFIILIRDNFPFNAFLAGFIICVGQFVLLMSLRLQLCNSFPGISKNRAFAEFIVASLILHFVCLHFIN

来源 Source

来源生物 organism	Saccharomyces cerevisiae
通用名 common_name	;baker's yeast ;
NCBI 分类编号 ncbi_taxonomy_id	4932
宿主生物 host_organism	Saccharomyces cerevisiae

实体 5 Entity 5 polymer

描述 description	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1
分子量 formula_weight	54116.5 kDa
来源方法 src_method	man
拷贝数 entity_count	1

聚合物 Polymer

聚合物类型 type	polypeptide(L)
链编号 strand_id	E

MRQVWFSWIVGLFLCFFNVSSAAQYEPPATWENVDYKRTIDVSNAYISETIEITIKNIASEPATEYFTAFESGIFSKVSFFSAYFTNEATFLNSQLLANSTTAPGDDGESEIRYGIIQFPNAISPQEEVSLVIKSFYNTVGIPYPEHVGMSEEQHLLWETNRLPLSAYDTKKASFTLIGSSSFEEYHPPNDESLLGKANGNSFEFGPWEDIPRFSSNETLAIVYSHNAPLNQVVNLRRDIWLSHWASTIQFEEYYELTNKAAKLSKGFSRLELMKQIQTQNMRQTHFVTVLDMLLPEGATDHYFTDLVGLVSTSHAERDHFFIRPRFPIFGGWNYNFTVGWTNKLSDFLHVSSGSDEKFVASIPILNGPPDTVYDNVELSVFLPEGAEIFDIDSPVPFTNVSIETQKSYFDLNKGHVKLTFSYRNLISQVANGQVLIKYDYPKSSFFKKPLSIACYIFTALMGVFVLKTLNMNVTN

来源 Source

来源生物 organism	Saccharomyces cerevisiae
通用名 common_name	;baker's yeast ;
NCBI 分类编号 ncbi_taxonomy_id	4932
宿主生物 host_organism	Saccharomyces cerevisiae

实体 6 Entity 6 polymer

描述 description	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2
分子量 formula_weight	31340.4 kDa
来源方法 src_method	man
拷贝数 entity_count	1

聚合物 Polymer

聚合物类型 type	polypeptide(L)
链编号 strand_id	F

MQFFKTLAALVSCISFVLAYVAQDVHVSFPSTAGKSRVMIGKVEPRIGIDETVPTTITVEDPNEVIQVNFAIESTNKPFQNTLLIGLPNKNLEMAFEPEIKDNGKLSMYKYRIDLAKLDAALLQEASRSPEPIKATLILASSTAKPKENLFREILQLNLNFDVDHSDSSLVDKFGIKPEIHHIFHAEPKRVAKPIAVIFVLIIFITILSLIVTWLNSCAAAFNNIPTGVTAVYFLGFIATIVGFEVIFARYYLGTSIFETLFSSLYLGAPGLLTSTKFLRSFG

来源 Source

来源生物 organism	Saccharomyces cerevisiae
通用名 common_name	;baker's yeast ;
NCBI 分类编号 ncbi_taxonomy_id	4932
宿主生物 host_organism	Saccharomyces cerevisiae

实体 7 Entity 7 polymer

描述 description	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1
分子量 formula_weight	49444.4 kDa
来源方法 src_method	man
拷贝数 entity_count	1

聚合物 Polymer

聚合物类型 type	polypeptide(L)
链编号 strand_id	G

MRTDWNFFFCILLQAIFVVGTQTSRTLVLYDQSTEPLEEYSVYLKDLEQRNYKLEYLDINSTSTTVDLYDKEQRLFDNIIVFPTKGGKNLARQIPVKQLIKFFENEGNILCMSSPGAVPNTIRLFLNELGIYPSPKGHVIRDYFSPSSEELVVSSNHLLNKYVYNARKSEDFVFGESSAALLENREQIVPILNAPRTSFTESKGKCNSWTSGSQGFLVVGFQNLNNARLVWIGSSDFLKNKNQDSNQEFAKELLKWTFNEKSVIKSVHAVHSHADGTSYDEEPYKIKDKVIYSVGFSEWNGEEWLPHIADDIQFELRQVDPYYRLTLSPSGNDSETQYYTTGEFILPDRHGVFTFLTDYRKIGLSFTTDKDVKAIRHLANDEYPRSWEISNSWVYISAICGVIVAWIFFVVSFVTTSSVGKKLETFKKTN

来源 Source

来源生物 organism	Saccharomyces cerevisiae
通用名 common_name	;baker's yeast ;
NCBI 分类编号 ncbi_taxonomy_id	4932
宿主生物 host_organism	Saccharomyces cerevisiae

实体 8 Entity 8 polymer

描述 description	OST3 isoform 1
分子量 formula_weight	39518.2 kDa
来源方法 src_method	man
拷贝数 entity_count	1

聚合物 Polymer

聚合物类型 type	polypeptide(L)
链编号 strand_id	H

MNWLFLVSLVFFCGVSTHPALAMSSNRLLKLANKSPKKIIPLKDSSFENILAPPHENAYIVALFTATAPEIGCSLCLELESEYDTIVASWFDDHPDAKSSNSDTSIFFTKVNLEDPSKTIPKAFQFFQLNNVPRLFIFKPNSPSILDHSVISISTDTGSERMKQIIQAIKQFSQVNDFSLHLPMDWTPIITSTIITFITVLLFKKQSKLMFSIISSRIIWATLSTFFIICMISAYMFNQIRNTQLAGVGPKGEVMYFLPNEFQHQFAIETQVMVLIYGTLAALVVVLVKGIQFLRSHLYPETKKAYFIDAILASFCALFIYVFFAALTTVFTIKSPAYPFPLLRLSAPFK

来源 Source

来源生物 organism	Saccharomyces cerevisiae
通用名 common_name	;baker's yeast ;
NCBI 分类编号 ncbi_taxonomy_id	4932
宿主生物 host_organism	Saccharomyces cerevisiae

实体 9 Entity 9 polymer

描述 description	PEPTIDE
分子量 formula_weight	682.7 kDa
来源方法 src_method	syn
拷贝数 entity_count	1

聚合物 Polymer

聚合物类型 type	polypeptide(L)
链编号 strand_id	P

YAAATSA

实体 10 Entity 10 branched

描述 description	;alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ;
分子量 formula_weight	1235.1 kDa
来源方法 src_method	man
拷贝数 entity_count	1

实体 11 Entity 11 branched

描述 description	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
分子量 formula_weight	424.4 kDa
来源方法 src_method	man
拷贝数 entity_count	2

实体 12 Entity 12 branched

描述 description	;alpha-D-glucopyranose-(1-2)-alpha-D-glucopyranose-(1-3)-alpha-D-glucopyranose-(1-3)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose ;
分子量 formula_weight	1883.7 kDa
来源方法 src_method	syn
拷贝数 entity_count	1

实体 13 Entity 13 non-polymer

描述 description	phosphono [(3~{R},6~{E},10~{E})-3,7,11,15-tetramethylhexadeca-6,10,14-trienyl] hydrogen phosphate
分子量 formula_weight	452.5 kDa
来源方法 src_method	syn
拷贝数 entity_count	1

实体 14 Entity 14 non-polymer

描述 description	1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
分子量 formula_weight	758.1 kDa
来源方法 src_method	syn
拷贝数 entity_count	4

实体 15 Entity 15 non-polymer

描述 description	PHOSPHATIDYLETHANOLAMINE
分子量 formula_weight	734.0 kDa
来源方法 src_method	syn
拷贝数 entity_count	2

实体 16 Entity 16 non-polymer

描述 description	MANGANESE (II) ION
分子量 formula_weight	54.9 kDa
来源方法 src_method	syn
拷贝数 entity_count	1

实体 17 Entity 17 non-polymer

描述 description	2-acetamido-2-deoxy-beta-D-glucopyranose
分子量 formula_weight	221.2 kDa
来源方法 src_method	syn
拷贝数 entity_count	2

实体 18 Entity 18 non-polymer

描述 description	2-[3,6-bis(dimethylamino)xanthen-9-yl]-5-methanoyl-benzoate
分子量 formula_weight	414.5 kDa
来源方法 src_method	syn
拷贝数 entity_count	1

▼

6. 折叠分类 (SCOP + CATH) 1 domains

CATH v4.4 (1 domains)

结构域编号 domain_id	8agcA01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	40 — 3-Layer(aba) Sandwich
拓扑 Topology topology	50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily	12610 —

▶

晶胞边长 a length_a	1.000 Å
晶胞边长 b length_b	1.000 Å
晶胞边长 c length_c	1.000 Å
晶胞夹角 α angle_alpha	90.00 °
晶胞夹角 β angle_beta	90.00 °
晶胞夹角 γ angle_gamma	90.00 °
晶胞分子数 Z z_pdb	—

空间群 space_group	P 1
空间群编号 int_tables_number	1
晶系 crystal_system	—

分辨率 resolution	3.10 Å
分辨率测定方法 resolution_method	—
颗粒数 num_particles	75382

Structure of yeast oligosaccharylransferase complex with lipid-linked oligosaccharide and non-acceptor peptide bound

1. 蛋白身份与相关结构 Protein Identity & Related Structures

Dolichyl-diphosphooligosaccharide--protein glycotransferase

当前结构中的状态

数据库中的同蛋白其他状态

单体

同源二聚体

同源四聚体

其他同源多聚体

异源或核酸复合物

OST4 isoform 1

当前结构中的状态

数据库中的同蛋白其他状态

单体

同源二聚体

同源四聚体

其他同源多聚体

异源或核酸复合物

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST5

当前结构中的状态

数据库中的同蛋白其他状态

单体

同源二聚体

同源四聚体

其他同源多聚体

异源或核酸复合物

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2

当前结构中的状态

数据库中的同蛋白其他状态

单体

同源二聚体

同源四聚体

其他同源多聚体

异源或核酸复合物

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

当前结构中的状态

数据库中的同蛋白其他状态

单体

同源二聚体

同源四聚体

其他同源多聚体

异源或核酸复合物

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

当前结构中的状态

数据库中的同蛋白其他状态

单体

同源二聚体

同源四聚体

其他同源多聚体

异源或核酸复合物

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1

当前结构中的状态

数据库中的同蛋白其他状态

单体

同源二聚体

同源四聚体

其他同源多聚体

异源或核酸复合物

OST3 isoform 1

当前结构中的状态

数据库中的同蛋白其他状态

单体

同源二聚体

同源四聚体

其他同源多聚体

异源或核酸复合物

2. 结构基本信息 2. Structure Basics

3. Official assembly/model 理论 SAXS Official SAXS Profiles

8agc__assembly_1__model_1

8agc__assembly_1__model_1 | I(q)

8agc__assembly_1__model_1 | P(r) · Pending

4. 晶体学与实验 4. Crystallography & Experiment

晶胞参数 Unit Cell

对称性 Symmetry

冷冻电镜 EM 3D

5. 实体与聚合物信息 Entities & Polymers (18)

实体 1 Entity 1 polymer

聚合物 Polymer

来源 Source

实体 2 Entity 2 polymer