8ajz

Serial femtosecond crystallography structure of CO bound ba3- type cytochrome c oxidase at 2 milliseconds after irradiation by a 532 nm laser

Method: X-RAY DIFFRACTION D_max: 88.9 Å Quality: GOOD

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1. 蛋白身份与相关结构 Protein Identity & Related Structures

Cytochrome c oxidase subunit 1

Thermus thermophilus

当前结构中的状态

Assembly	聚集状态	构建体	突变与修饰	配体、离子与共同组分	实验方法与环境	结构质量
1	蛋白异源复合物异源复合物蛋白 × 3 PDB 声明：trimeric（3）与蛋白拷贝数一致	链 A； UniProt 2–562	未记录	Cytochrome c oxidase subunit 2 × 1 （Q5SJ80） Cytochrome c oxidase polypeptide IIA × 1 （A0A1J1EEV7） CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件：LIPIDIC CUBIC PHASE；pH 5.3；298 K；100 mM 2-Morpholinoethanesulfonic acid, 34-38 % PEG 400 (v/v), 1.4 M NaCl, pH 5.3	分辨率 2.00 Å R-free 0.210

数据库中的同蛋白其他状态

以下每一行都是同一 UniProt 蛋白在另一个 PDB 条目中的 biological assembly， “相对当前条目”直接指出证据层面的不同；没有差异标签表示当前已读取字段一致。

其他 PDB	相对当前条目 8AJZ	Assembly / 聚集状态	构建体	突变与修饰	配体、离子与非聚合物	实验方法与环境	结构质量
1EHK CRYSTAL STRUCTURE OF THE ABERRANT BA3-CYTOCHROME-C OXIDASE FROM THERMUS THERMOPHILUS 提交 2000-02-21	构建体不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 A 1–562（562 aa）片段：SUBUNIT I	未记录	BNG nonyl beta-D-glucopyranoside × 3 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；293 K；PEG 2000, Bis-Tris buffer, nonyl-beta-D-glucoside, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 293K	分辨率 2.40 Å R-free 0.264
2QPD An unexpected outcome of surface-engineering an integral membrane protein: Improved crystallization of cytochrome ba3 oxidase from Thermus thermophilus 提交 2007-07-23	突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 A 2–562（561 aa）	突变：K258R	CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；291 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris pH 7.0, 6.5 mM n-nonyl-beta-D-glucopyranoside, VAPOR DIFFUSION, SITTING DROP, temperature 291K	分辨率 3.25 Å R-free 0.307
2QPE An unexpected outcome of surface-engineering an integral membrane protein: Improved crystallization of cytochrome ba3 oxidase from Thermus thermophilus 提交 2007-07-23	突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 A 2–562（561 aa）	突变：K258R	CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；291 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris, pH 7.0, 6.5 mM n-nonyl-beta-D-glucopyranoside, VAPOR DIFFUSION, SITTING DROP, temperature 291K	分辨率 2.90 Å R-free 0.302
3BVD Structure of Surface-engineered Cytochrome ba3 Oxidase from Thermus thermophilus under Xenon Pressure, 100psi 5min 提交 2008-01-07	突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 A 2–562（561 aa）	突变：K258R	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 7 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION；pH 7；297 K；6-9% PEG 2000, 50mM KCl, 7.5-30mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside , VAPOR DIFFUSION, temperature 297K	分辨率 3.37 Å R-free 0.336
3EH3 Structure of the reduced form of cytochrome ba3 oxidase from Thermus thermophilus 提交 2008-09-11	构建体不同突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 A 2–562（561 aa）片段：UNP residues 6-562	突变：K258R	CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；Peg 2000, Bis-tris, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 297K	分辨率 3.10 Å R-free 0.300
3EH3 Structure of the reduced form of cytochrome ba3 oxidase from Thermus thermophilus 提交 2008-09-11	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 2 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 A 2–562（561 aa）片段：UNP residues 6-562	突变：K258R	CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；Peg 2000, Bis-tris, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 297K	分辨率 3.10 Å R-free 0.300
3EH4 Structure of the reduced form of cytochrome ba3 oxidase from Thermus thermophilus 提交 2008-09-11	构建体不同突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 A 2–562（561 aa）片段：UNP residues 2-562	突变：K258R	CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CUA DINUCLEAR COPPER ION × 1 BNG nonyl beta-D-glucopyranoside × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；Peg 2000, Bis-tris, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 297K	分辨率 2.90 Å R-free 0.268
3EH4 Structure of the reduced form of cytochrome ba3 oxidase from Thermus thermophilus 提交 2008-09-11	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 2 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 A 2–562（561 aa）片段：UNP residues 2-562	突变：K258R	CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；Peg 2000, Bis-tris, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 297K	分辨率 2.90 Å R-free 0.268
3EH5 Structure of the reduced form of cytochrome ba3 oxidase from Thermus thermophilus 提交 2008-09-11	构建体不同突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 A 2–562（561 aa）片段：UNP residues 2-562	突变：K258R	CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 BNG nonyl beta-D-glucopyranoside × 4 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；Peg 2000, Bis-tris, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 297K	分辨率 2.80 Å R-free 0.257
3EH5 Structure of the reduced form of cytochrome ba3 oxidase from Thermus thermophilus 提交 2008-09-11	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 2 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 A 2–562（561 aa）片段：UNP residues 2-562	突变：K258R	CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 BNG nonyl beta-D-glucopyranoside × 3	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；Peg 2000, Bis-tris, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 297K	分辨率 2.80 Å R-free 0.257
3QJQ The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus 提交 2011-01-30	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 A 2–562（561 aa）	未记录	CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris pH 7.0, 6.5 mM n-nonyl-beta-D glucopyranoside, VAPOR DIFFUSION, SITTING DROP, temperature 297K	分辨率 2.90 Å R-free 0.284
3QJR The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus 提交 2011-01-30	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 A 2–562（561 aa）	未记录	CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris pH 7.0, 6.5 mM n-nonyl-beta-D-glucopyranoside , VAPOR DIFFUSION, SITTING DROP, temperature 297K	分辨率 3.20 Å R-free 0.367
3QJS The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus 提交 2011-01-30	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 A 2–562（561 aa）	未记录	CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris pH 7.0, 6.5 mM n-nonyl-beta-D-glucopyranoside , VAPOR DIFFUSION, SITTING DROP, temperature 297K	分辨率 2.80 Å R-free 0.265
3QJT The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus 提交 2011-01-30	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 A 2–562（561 aa）	未记录	CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris pH 7.0, 6.5 mM n-nonyl-beta-D-glucopyranoside , VAPOR DIFFUSION, SITTING DROP, temperature 297K	分辨率 2.95 Å R-free 0.323
3QJU The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus 提交 2011-01-30	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 A 2–562（561 aa）	未记录	CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris pH 7.0, 6.5 mM n-nonyl-beta-D-glucopyranoside, VAPOR DIFFUSION, SITTING DROP, temperature 297K	分辨率 2.90 Å R-free 0.329
3QJV The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus 提交 2011-01-30	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 A 2–562（561 aa）	未记录	CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris pH 7.0, 6.5 mM n-nonyl-beta-D-glucopyranoside, VAPOR DIFFUSION, SITTING DROP, temperature 297K	分辨率 2.80 Å R-free 0.274
3S33 Structure of Thermus thermophilus cytochrome ba3 oxidase 10s after Xe depressurization 提交 2011-05-17	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 A 2–562（561 aa）	未记录	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 5 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7；297 K；12-17% PEG 2000, 0-200mM KCl, 15-60mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside, vapor diffusion, hanging drop, temperature 297K	分辨率 4.45 Å R-free 0.350
3S38 Structure of Thermus thermophilus cytochrome ba3 oxidase 30s after Xe depressurization 提交 2011-05-17	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 A 2–562（561 aa）	未记录	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 4 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7；297 K；12-17% PEG 2000, 0-200mM KCl, 15-60mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside, vapor diffusion, hanging drop, temperature 297K	分辨率 4.20 Å R-free 0.325
3S39 Structure of Thermus thermophilus cytochrome ba3 oxidase 60s after Xe depressurization 提交 2011-05-17	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 A 2–562（561 aa）	未记录	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 4 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7；297 K；12-17% PEG 2000, 0-200mM KCl, 15-60mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside, vapor diffusion, hanging drop, temperature 297K	分辨率 4.80 Å R-free 0.341
3S3A Structure of Thermus thermophilus cytochrome ba3 oxidase 120s after Xe depressurization 提交 2011-05-18	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 A 2–562（561 aa）	未记录	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 4 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7；297 K；12-17% PEG 2000, 0-200mM KCl, 15-60mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside, vapor diffusion, hanging drop, temperature 297K	分辨率 4.25 Å R-free 0.330
3S3B Structure of Thermus thermophilus cytochrome ba3 oxidase 240s after Xe depressurization 提交 2011-05-18	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 A 2–562（561 aa）	未记录	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 3 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7；297 K；12-17% PEG 2000, 0-200mM KCl, 15-60mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside, vapor diffusion, hanging drop, temperature 297K	分辨率 3.30 Å R-free 0.299
3S3C Structure of Thermus thermophilus cytochrome ba3 oxidase 360s after Xe depressurization 提交 2011-05-18	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 A 2–562（561 aa）	未记录	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 3 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 pH 7；297 K；12-17% PEG 2000, 0-200mM KCl, 15-60mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside, vapor diffusion, hanging drop, temperature 297K	分辨率 4.00 Å R-free 0.373
3S3D Structure of Thermus thermophilus cytochrome ba3 oxidase 480s after Xe depressurization 提交 2011-05-18	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 A 2–562（561 aa）	未记录	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 3 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 pH 7；297 K；12-17% PEG 2000, 0-200mM KCl, 15-60mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside, vapor diffusion, hanging drop, temperature 297K	分辨率 3.75 Å R-free 0.293
3S8F 1.8 A structure of ba3 cytochrome c oxidase from Thermus thermophilus in lipid environment 提交 2011-05-27	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 A 2–562（561 aa）	未记录	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6；293 K；40-45% PEG 400, 1.0-1.6M NaCl, 100mM sodium cacodylate trihydrate pH 5.5-6.5, lipidic cubic phase with monolein, temperature 293K	分辨率 1.80 Å R-free 0.215
3S8G 1.8 A structure of ba3 cytochrome c oxidase mutant (A120F) from Thermus thermophilus in lipid environment 提交 2011-05-27	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 A 2–562（561 aa）	未记录	HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CU COPPER (II) ION × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 20 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 LIPIDIC CUBIC PHASE；293 K；40-45% PEG 400, 1.0-1.6M NaCl, 100mM sodium cacodylate trihydrate pH 5.5-6.5, lipidic cubic phase with monolein, temperature 293K	分辨率 1.80 Å R-free 0.196
4FA7 Structure of Recombinant Cytochrome ba3 Oxidase mutant A204F from Thermus thermophilus 提交 2012-05-21	突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 A 2–562（561 aa）	突变：A204F	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PEO HYDROGEN PEROXIDE × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate, 1.6M NaCl, 40% PEG400, pH 6.5, Lipidic Cubic Phase, temperature 293K	分辨率 2.50 Å R-free 0.220
4FAA Structure of Recombinant Cytochrome ba3 Oxidase mutant A120F+A204F from Thermus thermophilus 提交 2012-05-21	突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 A 2–562（561 aa）	突变：Y120F,204F	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PEO HYDROGEN PEROXIDE × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate, 1.6M NaCl, 40% PEG400, pH 6.5, Lipidic Cubic Phase, temperature 293K	分辨率 2.80 Å R-free 0.254
4G70 Structure of Recombinant Cytochrome ba3 Oxidase mutant V236T from Thermus thermophilus 提交 2012-07-19	突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 A 2–562（561 aa）	突变：A120F, V236T	HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CU COPPER (II) ION × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate PH 6.5, 1.6M NaCl, 40% PEG400 , Lipidic Cubic Phase, temperature 293K	分辨率 2.60 Å R-free 0.252
4G71 Structure of Recombinant Cytochrome ba3 Oxidase mutant V236N from Thermus thermophilus 提交 2012-07-19	突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 A 2–562（561 aa）	突变：A120F, V236N	CUB CU(I)-S-MO(IV)(=O)O-NBIC CLUSTER × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate PH 6.5, 1.6M NaCl, 40% PEG400 , Lipidic Cubic Phase, temperature 293K	分辨率 2.90 Å R-free 0.224
4G72 Structure of Recombinant Cytochrome ba3 Oxidase mutant V236M from Thermus thermophilus 提交 2012-07-19	突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 A 2–562（561 aa）	突变：A120F, V236M	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate PH 6.5, 1.6M NaCl, 40% PEG400 , Lipidic Cubic Phase, temperature 293K	分辨率 3.19 Å R-free 0.223
4G7Q Structure of Recombinant Cytochrome ba3 Oxidase mutant V236L from Thermus thermophilus 提交 2012-07-20	突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 A 2–562（561 aa）	突变：A120F, V236L	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate PH 6.5, 1.6M NaCl, 40% PEG400 , Lipidic Cubic Phase, temperature 293K	分辨率 2.60 Å R-free 0.232
4G7R Structure of Recombinant Cytochrome ba3 Oxidase mutant V236A from Thermus thermophilus 提交 2012-07-20	突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 A 2–562（561 aa）	突变：A120F, V236A	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION mmCIF 未提供已读取条件	分辨率 3.05 Å R-free 0.231
4G7S Structure of Recombinant Cytochrome ba3 Oxidase mutant V236I from Thermus thermophilus 提交 2012-07-20	突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 A 2–562（561 aa）	突变：A120F, V236I	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate PH 6.5, 1.6M NaCl, 40% PEG400 , Lipidic Cubic Phase, temperature 293K	分辨率 2.00 Å R-free 0.207
4GP4 Structure of Recombinant Cytochrome ba3 Oxidase mutant Y133F from Thermus thermophilus 提交 2012-08-20	突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 A 2–562（561 aa）	突变：Y133F	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate, 1.6M NaCl, 40% PEG400, pH 6.5, Lipidic Cubic Phase, temperature 293K	分辨率 2.80 Å R-free 0.227
4GP5 Structure of Recombinant Cytochrome ba3 Oxidase mutant Y133W from Thermus thermophilus 提交 2012-08-20	突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 A 2–562（561 aa）	突变：Y133W	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate, 1.6M NaCl, 40% PEG400, pH 6.5, Lipidic Cubic Phase, temperature 293K	分辨率 2.70 Å R-free 0.230
4GP8 Structure of Recombinant Cytochrome ba3 Oxidase mutant Y133W+T231F from Thermus thermophilus 提交 2012-08-20	突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 A 2–562（561 aa）	突变：Y133W, T231F	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate, 1.6M NaCl, 40% PEG400, pH 6.5, Lipidic Cubic Phase, temperature 293K	分辨率 2.80 Å R-free 0.227
4N4Y Structure of Recombinant Cytochrome ba3 Oxidase mutant G232V from Thermus thermophilus 提交 2013-10-08	突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 A 2–562（561 aa）	突变：G232V	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PEO HYDROGEN PEROXIDE × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50 mM sodium cacodylate, pH 6.5, 1.6 M sodium chloride, 40% PEG400, LIPIDIC CUBIC PHASE, temperature 293K	分辨率 2.90 Å R-free 0.225
5NDC Structure of ba3-type cytochrome c oxidase from Thermus thermophilus by serial femtosecond crystallography 提交 2017-03-08	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 A 2–562（561 aa）	未记录	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 5.3；293 K；100mM sodium cacodylate trihydrate pH 5.3, 37% PEG400, 1.4M NaCl Room temperature for 2-3 days	分辨率 2.30 Å R-free 0.197
8HUA Serial synchrotron crystallography structure of ba3-type cytochrome c oxidase from Thermus thermophilus using a goniometer compatible flow-cell 提交 2022-12-22	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 A 2–562（561 aa）	未记录	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 5.3；298 K；1.4 M NaCl, 100 mM MES pH 5.3 with 36 % to 39 % (v/v) PEG 400	分辨率 2.12 Å R-free 0.184
8K65 Serial femtosecond crystallography structure of CO bound ba3- type cytochrome c oxidase without pump laser irradiation 提交 2023-07-25	实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 A 2–562（561 aa）	未记录	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 5.3；293 K；34-38 % PEG 400 (v/v), 1.4 M NaCl, pH 5.3	分辨率 2.00 Å R-free 0.196
8K6Y Serial femtosecond crystallography structure of photo dissociated CO from ba3- type cytochrome c oxidase determined by extrapolation method 提交 2023-07-25	实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 A 2–562（561 aa）	未记录	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 5.3；293 K；34-38 % PEG 400 (v/v), 1.4 M NaCl, pH 5.3	分辨率 2.00 Å R-free 0.435
9GDF Chloride bound structure of oxidized ba3-type cytochrome c oxidase confirmed by single-wavelength anomalous diffraction 提交 2024-08-05	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 A 2–562（561 aa）	未记录	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CL CHLORIDE ION × 2 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 5.3；298 K；1.4 M NaCl, 100 mM MES. 40-43 % (v/v) PEG 400	分辨率 2.28 Å R-free 0.197
9VDJ Serial synchrotron crystallography structure of a ba3-type cytochrome c oxidase using a goniometer-compatible chip-based platform 提交 2025-06-08	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 A 2–562（561 aa）	未记录	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 LIPIDIC CUBIC PHASE；293 K；0.1M MES (pH 5.3), 1.4M NaCl, 39-41% PEG 400	分辨率 2.30 Å R-free 0.264

共 40 个其他 PDB 条目、43 个 assembly。打开独立比较页并筛选聚集状态

查看构建体与数据证据

UniProt名称	COX1_THET8
Isoform	—
PDB实体	1
链与序列区间	作者链 A； PDB构建体 9–569； UniProt 2–562

Cytochrome c oxidase subunit 2

Thermus thermophilus

UniProt Q5SJ80

当前结构中的状态

Assembly	聚集状态	构建体	突变与修饰	配体、离子与共同组分	实验方法与环境	结构质量
1	蛋白异源复合物异源复合物蛋白 × 3 PDB 声明：trimeric（3）与蛋白拷贝数一致	链 B； UniProt 1–168	未记录	Cytochrome c oxidase subunit 1 × 1 （Q5SJ79） Cytochrome c oxidase polypeptide IIA × 1 （A0A1J1EEV7） CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件：LIPIDIC CUBIC PHASE；pH 5.3；298 K；100 mM 2-Morpholinoethanesulfonic acid, 34-38 % PEG 400 (v/v), 1.4 M NaCl, pH 5.3	分辨率 2.00 Å R-free 0.210

数据库中的同蛋白其他状态

其他 PDB	相对当前条目 8AJZ	Assembly / 聚集状态	构建体	突变与修饰	配体、离子与非聚合物	实验方法与环境	结构质量
1EHK CRYSTAL STRUCTURE OF THE ABERRANT BA3-CYTOCHROME-C OXIDASE FROM THERMUS THERMOPHILUS 提交 2000-02-21	构建体不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 B 1–168（168 aa）片段：SUBUNIT II	未记录	BNG nonyl beta-D-glucopyranoside × 3 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；293 K；PEG 2000, Bis-Tris buffer, nonyl-beta-D-glucoside, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 293K	分辨率 2.40 Å R-free 0.264
2QPD An unexpected outcome of surface-engineering an integral membrane protein: Improved crystallization of cytochrome ba3 oxidase from Thermus thermophilus 提交 2007-07-23	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 B 1–168（168 aa）	未记录	CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；291 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris pH 7.0, 6.5 mM n-nonyl-beta-D-glucopyranoside, VAPOR DIFFUSION, SITTING DROP, temperature 291K	分辨率 3.25 Å R-free 0.307
2QPE An unexpected outcome of surface-engineering an integral membrane protein: Improved crystallization of cytochrome ba3 oxidase from Thermus thermophilus 提交 2007-07-23	突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 B 1–168（168 aa）	突变：E4Q	CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；291 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris, pH 7.0, 6.5 mM n-nonyl-beta-D-glucopyranoside, VAPOR DIFFUSION, SITTING DROP, temperature 291K	分辨率 2.90 Å R-free 0.302
3BVD Structure of Surface-engineered Cytochrome ba3 Oxidase from Thermus thermophilus under Xenon Pressure, 100psi 5min 提交 2008-01-07	突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 B 1–168（168 aa）	突变：E4Q	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 7 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION；pH 7；297 K；6-9% PEG 2000, 50mM KCl, 7.5-30mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside , VAPOR DIFFUSION, temperature 297K	分辨率 3.37 Å R-free 0.336
3EH3 Structure of the reduced form of cytochrome ba3 oxidase from Thermus thermophilus 提交 2008-09-11	构建体不同突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 B 3–168（166 aa）片段：UNP residues 3-168	突变：E4Q	CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；Peg 2000, Bis-tris, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 297K	分辨率 3.10 Å R-free 0.300
3EH3 Structure of the reduced form of cytochrome ba3 oxidase from Thermus thermophilus 提交 2008-09-11	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 3 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 B 3–168（166 aa）片段：UNP residues 3-168	突变：E4Q	CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；Peg 2000, Bis-tris, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 297K	分辨率 3.10 Å R-free 0.300
3EH4 Structure of the reduced form of cytochrome ba3 oxidase from Thermus thermophilus 提交 2008-09-11	构建体不同突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 B 3–168（166 aa）片段：UNP residues 3-168	突变：E4Q	CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CUA DINUCLEAR COPPER ION × 1 BNG nonyl beta-D-glucopyranoside × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；Peg 2000, Bis-tris, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 297K	分辨率 2.90 Å R-free 0.268
3EH4 Structure of the reduced form of cytochrome ba3 oxidase from Thermus thermophilus 提交 2008-09-11	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 3 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 B 3–168（166 aa）片段：UNP residues 3-168	突变：E4Q	CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；Peg 2000, Bis-tris, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 297K	分辨率 2.90 Å R-free 0.268
3EH5 Structure of the reduced form of cytochrome ba3 oxidase from Thermus thermophilus 提交 2008-09-11	构建体不同突变/修饰不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 B 3–168（166 aa）片段：UNP residues 3-168	突变：E4Q	CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 BNG nonyl beta-D-glucopyranoside × 4 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；Peg 2000, Bis-tris, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 297K	分辨率 2.80 Å R-free 0.257
3EH5 Structure of the reduced form of cytochrome ba3 oxidase from Thermus thermophilus 提交 2008-09-11	构建体不同突变/修饰不同聚集状态不同配体/离子不同实验环境不同结构质量不同	Assembly 3 蛋白单体单体；蛋白 × 1 PDB 声明：monomeric	链 B 3–168（166 aa）片段：UNP residues 3-168	突变：E4Q	CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；Peg 2000, Bis-tris, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 297K	分辨率 2.80 Å R-free 0.257
3QJQ The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus 提交 2011-01-30	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 B 1–168（168 aa）	未记录	CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris pH 7.0, 6.5 mM n-nonyl-beta-D glucopyranoside, VAPOR DIFFUSION, SITTING DROP, temperature 297K	分辨率 2.90 Å R-free 0.284
3QJR The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus 提交 2011-01-30	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 B 1–168（168 aa）	未记录	CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris pH 7.0, 6.5 mM n-nonyl-beta-D-glucopyranoside , VAPOR DIFFUSION, SITTING DROP, temperature 297K	分辨率 3.20 Å R-free 0.367
3QJS The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus 提交 2011-01-30	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 B 1–168（168 aa）	未记录	CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris pH 7.0, 6.5 mM n-nonyl-beta-D-glucopyranoside , VAPOR DIFFUSION, SITTING DROP, temperature 297K	分辨率 2.80 Å R-free 0.265
3QJT The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus 提交 2011-01-30	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 B 1–168（168 aa）	未记录	CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris pH 7.0, 6.5 mM n-nonyl-beta-D-glucopyranoside , VAPOR DIFFUSION, SITTING DROP, temperature 297K	分辨率 2.95 Å R-free 0.323
3QJU The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus 提交 2011-01-30	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 B 1–168（168 aa）	未记录	CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris pH 7.0, 6.5 mM n-nonyl-beta-D-glucopyranoside, VAPOR DIFFUSION, SITTING DROP, temperature 297K	分辨率 2.90 Å R-free 0.329
3QJV The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus 提交 2011-01-30	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 B 1–168（168 aa）	未记录	CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris pH 7.0, 6.5 mM n-nonyl-beta-D-glucopyranoside, VAPOR DIFFUSION, SITTING DROP, temperature 297K	分辨率 2.80 Å R-free 0.274
3S33 Structure of Thermus thermophilus cytochrome ba3 oxidase 10s after Xe depressurization 提交 2011-05-17	构建体不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 B 3–168（166 aa）	未记录	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 5 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7；297 K；12-17% PEG 2000, 0-200mM KCl, 15-60mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside, vapor diffusion, hanging drop, temperature 297K	分辨率 4.45 Å R-free 0.350
3S38 Structure of Thermus thermophilus cytochrome ba3 oxidase 30s after Xe depressurization 提交 2011-05-17	构建体不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 B 3–168（166 aa）	未记录	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 4 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7；297 K；12-17% PEG 2000, 0-200mM KCl, 15-60mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside, vapor diffusion, hanging drop, temperature 297K	分辨率 4.20 Å R-free 0.325
3S39 Structure of Thermus thermophilus cytochrome ba3 oxidase 60s after Xe depressurization 提交 2011-05-17	构建体不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 B 3–168（166 aa）	未记录	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 4 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7；297 K；12-17% PEG 2000, 0-200mM KCl, 15-60mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside, vapor diffusion, hanging drop, temperature 297K	分辨率 4.80 Å R-free 0.341
3S3A Structure of Thermus thermophilus cytochrome ba3 oxidase 120s after Xe depressurization 提交 2011-05-18	构建体不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 B 3–168（166 aa）	未记录	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 4 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7；297 K；12-17% PEG 2000, 0-200mM KCl, 15-60mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside, vapor diffusion, hanging drop, temperature 297K	分辨率 4.25 Å R-free 0.330
3S3B Structure of Thermus thermophilus cytochrome ba3 oxidase 240s after Xe depressurization 提交 2011-05-18	构建体不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 B 3–168（166 aa）	未记录	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 3 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 VAPOR DIFFUSION, HANGING DROP；pH 7；297 K；12-17% PEG 2000, 0-200mM KCl, 15-60mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside, vapor diffusion, hanging drop, temperature 297K	分辨率 3.30 Å R-free 0.299
3S3C Structure of Thermus thermophilus cytochrome ba3 oxidase 360s after Xe depressurization 提交 2011-05-18	构建体不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 B 3–168（166 aa）	未记录	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 3 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 pH 7；297 K；12-17% PEG 2000, 0-200mM KCl, 15-60mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside, vapor diffusion, hanging drop, temperature 297K	分辨率 4.00 Å R-free 0.373
3S3D Structure of Thermus thermophilus cytochrome ba3 oxidase 480s after Xe depressurization 提交 2011-05-18	构建体不同配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 B 3–168（166 aa）	未记录	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 3 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 pH 7；297 K；12-17% PEG 2000, 0-200mM KCl, 15-60mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside, vapor diffusion, hanging drop, temperature 297K	分辨率 3.75 Å R-free 0.293
3S8F 1.8 A structure of ba3 cytochrome c oxidase from Thermus thermophilus in lipid environment 提交 2011-05-27	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 B 1–168（168 aa）	未记录	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6；293 K；40-45% PEG 400, 1.0-1.6M NaCl, 100mM sodium cacodylate trihydrate pH 5.5-6.5, lipidic cubic phase with monolein, temperature 293K	分辨率 1.80 Å R-free 0.215
3S8G 1.8 A structure of ba3 cytochrome c oxidase mutant (A120F) from Thermus thermophilus in lipid environment 提交 2011-05-27	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 B 1–168（168 aa）	未记录	HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CU COPPER (II) ION × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 20 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 LIPIDIC CUBIC PHASE；293 K；40-45% PEG 400, 1.0-1.6M NaCl, 100mM sodium cacodylate trihydrate pH 5.5-6.5, lipidic cubic phase with monolein, temperature 293K	分辨率 1.80 Å R-free 0.196
4FA7 Structure of Recombinant Cytochrome ba3 Oxidase mutant A204F from Thermus thermophilus 提交 2012-05-21	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 B 1–168（168 aa）	未记录	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PEO HYDROGEN PEROXIDE × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate, 1.6M NaCl, 40% PEG400, pH 6.5, Lipidic Cubic Phase, temperature 293K	分辨率 2.50 Å R-free 0.220
4FAA Structure of Recombinant Cytochrome ba3 Oxidase mutant A120F+A204F from Thermus thermophilus 提交 2012-05-21	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 B 1–168（168 aa）	未记录	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PEO HYDROGEN PEROXIDE × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate, 1.6M NaCl, 40% PEG400, pH 6.5, Lipidic Cubic Phase, temperature 293K	分辨率 2.80 Å R-free 0.254
4G70 Structure of Recombinant Cytochrome ba3 Oxidase mutant V236T from Thermus thermophilus 提交 2012-07-19	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 B 1–168（168 aa）	未记录	HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CU COPPER (II) ION × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate PH 6.5, 1.6M NaCl, 40% PEG400 , Lipidic Cubic Phase, temperature 293K	分辨率 2.60 Å R-free 0.252
4G71 Structure of Recombinant Cytochrome ba3 Oxidase mutant V236N from Thermus thermophilus 提交 2012-07-19	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 B 1–168（168 aa）	未记录	CUB CU(I)-S-MO(IV)(=O)O-NBIC CLUSTER × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate PH 6.5, 1.6M NaCl, 40% PEG400 , Lipidic Cubic Phase, temperature 293K	分辨率 2.90 Å R-free 0.224
4G72 Structure of Recombinant Cytochrome ba3 Oxidase mutant V236M from Thermus thermophilus 提交 2012-07-19	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 B 1–168（168 aa）	未记录	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate PH 6.5, 1.6M NaCl, 40% PEG400 , Lipidic Cubic Phase, temperature 293K	分辨率 3.19 Å R-free 0.223
4G7Q Structure of Recombinant Cytochrome ba3 Oxidase mutant V236L from Thermus thermophilus 提交 2012-07-20	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 B 1–168（168 aa）	未记录	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate PH 6.5, 1.6M NaCl, 40% PEG400 , Lipidic Cubic Phase, temperature 293K	分辨率 2.60 Å R-free 0.232
4G7R Structure of Recombinant Cytochrome ba3 Oxidase mutant V236A from Thermus thermophilus 提交 2012-07-20	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 B 1–168（168 aa）	未记录	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION mmCIF 未提供已读取条件	分辨率 3.05 Å R-free 0.231
4G7S Structure of Recombinant Cytochrome ba3 Oxidase mutant V236I from Thermus thermophilus 提交 2012-07-20	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 B 1–168（168 aa）	未记录	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate PH 6.5, 1.6M NaCl, 40% PEG400 , Lipidic Cubic Phase, temperature 293K	分辨率 2.00 Å R-free 0.207
4GP4 Structure of Recombinant Cytochrome ba3 Oxidase mutant Y133F from Thermus thermophilus 提交 2012-08-20	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 B 1–168（168 aa）	未记录	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate, 1.6M NaCl, 40% PEG400, pH 6.5, Lipidic Cubic Phase, temperature 293K	分辨率 2.80 Å R-free 0.227
4GP5 Structure of Recombinant Cytochrome ba3 Oxidase mutant Y133W from Thermus thermophilus 提交 2012-08-20	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 B 1–168（168 aa）	未记录	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate, 1.6M NaCl, 40% PEG400, pH 6.5, Lipidic Cubic Phase, temperature 293K	分辨率 2.70 Å R-free 0.230
4GP8 Structure of Recombinant Cytochrome ba3 Oxidase mutant Y133W+T231F from Thermus thermophilus 提交 2012-08-20	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 B 1–168（168 aa）	未记录	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate, 1.6M NaCl, 40% PEG400, pH 6.5, Lipidic Cubic Phase, temperature 293K	分辨率 2.80 Å R-free 0.227
4N4Y Structure of Recombinant Cytochrome ba3 Oxidase mutant G232V from Thermus thermophilus 提交 2013-10-08	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 B 1–168（168 aa）	未记录	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PEO HYDROGEN PEROXIDE × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 6.5；293 K；50 mM sodium cacodylate, pH 6.5, 1.6 M sodium chloride, 40% PEG400, LIPIDIC CUBIC PHASE, temperature 293K	分辨率 2.90 Å R-free 0.225
5NDC Structure of ba3-type cytochrome c oxidase from Thermus thermophilus by serial femtosecond crystallography 提交 2017-03-08	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 B 1–168（168 aa）	未记录	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 5.3；293 K；100mM sodium cacodylate trihydrate pH 5.3, 37% PEG400, 1.4M NaCl Room temperature for 2-3 days	分辨率 2.30 Å R-free 0.197
8HUA Serial synchrotron crystallography structure of ba3-type cytochrome c oxidase from Thermus thermophilus using a goniometer compatible flow-cell 提交 2022-12-22	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 B 1–168（168 aa）	未记录	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 5.3；298 K；1.4 M NaCl, 100 mM MES pH 5.3 with 36 % to 39 % (v/v) PEG 400	分辨率 2.12 Å R-free 0.184
8K65 Serial femtosecond crystallography structure of CO bound ba3- type cytochrome c oxidase without pump laser irradiation 提交 2023-07-25	实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 B 1–168（168 aa）	未记录	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 5.3；293 K；34-38 % PEG 400 (v/v), 1.4 M NaCl, pH 5.3	分辨率 2.00 Å R-free 0.196
8K6Y Serial femtosecond crystallography structure of photo dissociated CO from ba3- type cytochrome c oxidase determined by extrapolation method 提交 2023-07-25	实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 B 1–168（168 aa）	未记录	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 5.3；293 K；34-38 % PEG 400 (v/v), 1.4 M NaCl, pH 5.3	分辨率 2.00 Å R-free 0.435
9GDF Chloride bound structure of oxidized ba3-type cytochrome c oxidase confirmed by single-wavelength anomalous diffraction 提交 2024-08-05	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 B 1–168（168 aa）	未记录	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CL CHLORIDE ION × 2 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 5.3；298 K；1.4 M NaCl, 100 mM MES. 40-43 % (v/v) PEG 400	分辨率 2.28 Å R-free 0.197
9VDJ Serial synchrotron crystallography structure of a ba3-type cytochrome c oxidase using a goniometer-compatible chip-based platform 提交 2025-06-08	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 B 1–168（168 aa）	未记录	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 LIPIDIC CUBIC PHASE；293 K；0.1M MES (pH 5.3), 1.4M NaCl, 39-41% PEG 400	分辨率 2.30 Å R-free 0.264

共 40 个其他 PDB 条目、43 个 assembly。打开独立比较页并筛选聚集状态

查看构建体与数据证据

UniProt名称	COX2_THET8
Isoform	—
PDB实体	2
链与序列区间	作者链 B； PDB构建体 1–168； UniProt 1–168

Cytochrome c oxidase polypeptide IIA

Thermus thermophilus

UniProt A0A1J1EEV7

当前结构中的状态

Assembly	聚集状态	构建体	突变与修饰	配体、离子与共同组分	实验方法与环境	结构质量
1	蛋白异源复合物异源复合物蛋白 × 3 PDB 声明：trimeric（3）与蛋白拷贝数一致	链 C； UniProt 26–59	未记录	Cytochrome c oxidase subunit 1 × 1 （Q5SJ79） Cytochrome c oxidase subunit 2 × 1 （Q5SJ80） CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件：LIPIDIC CUBIC PHASE；pH 5.3；298 K；100 mM 2-Morpholinoethanesulfonic acid, 34-38 % PEG 400 (v/v), 1.4 M NaCl, pH 5.3	分辨率 2.00 Å R-free 0.210

数据库中的同蛋白其他状态

其他 PDB	相对当前条目 8AJZ	Assembly / 聚集状态	构建体	突变与修饰	配体、离子与非聚合物	实验方法与环境	结构质量
5NDC Structure of ba3-type cytochrome c oxidase from Thermus thermophilus by serial femtosecond crystallography 提交 2017-03-08	配体/离子不同实验环境不同结构质量不同	Assembly 1 蛋白异源复合物异源复合物；蛋白 × 3 PDB 声明：trimeric	链 C 26–59（34 aa）	未记录	CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CUA DINUCLEAR COPPER ION × 1	X-RAY DIFFRACTION X-ray结晶条件 LIPIDIC CUBIC PHASE；pH 5.3；293 K；100mM sodium cacodylate trihydrate pH 5.3, 37% PEG400, 1.4M NaCl Room temperature for 2-3 days	分辨率 2.30 Å R-free 0.197

共 1 个其他 PDB 条目、1 个 assembly。打开独立比较页并筛选聚集状态

查看构建体与数据证据

UniProt名称	A0A1J1EEV7_THETH
Isoform	—
PDB实体	3
链与序列区间	作者链 C； PDB构建体 1–34； UniProt 26–59

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。

SAXS 散射曲线 SAXS Profile

P(r) 距离分布 P(r) Distribution

下载 Download SAXS (.dat) P(r) (.pr.out) CIF

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2. 结构基本信息 2. Structure Basics

条目编号 entry_id	8ajz
沉积日期 deposition_date	2022-07-29
结构标题 title	Serial femtosecond crystallography structure of CO bound ba3- type cytochrome c oxidase at 2 milliseconds after irradiation by a 532 nm laser
关键词 keywords	;Membrane protein, bioenergetics, lipidic cubic phase crystallization, serial femtosecond crystallography, pump- probe method, ELECTRON TRANSPORT ;; ELECTRON TRANSPORT
实验方法 method	X-RAY DIFFRACTION

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3. SAXS 参数 (CRYSOL 理论计算) 3. SAXS Parameters (CRYSOL)

回转半径 Rg (Guinier) rg_guinier	27.43 Å
回转半径 Rg (电子) rg_electron	26.12 Å
零角强度 I(0) i0	92047600.00
分子量 molecular_weight	88848.0 kDa
排除体积 excluded_volume	116620 Å³
包络体积 envelope_volume	130110 Å³
水化壳体积 shell_volume	39473 Å³
包络直径 envelope_diameter	90.5 Å
壳层 Rg shell_rg	35.19 Å
包络 Rg envelope_rg	26.56 Å
形状 Rg shape_rg	26.10 Å
总 Rg total_rg	27.21 Å
总原子数 total_atoms	6296
残基数 n_residues	752
球谐函数阶数 n_harmonics	20
q 范围 q_range	— – 0.5000 Å⁻¹
数据点数 n_points	101
壳层类型 shell_type	directional
溶剂电子密度 solvent_density	0.3340 e/Å³
壳层衬度 contrast_shell	0.0300 e/Å³
CRYSOL 版本 crysol_version	4.1.3

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4. P(r) 距离分布 (GNOM 反演) 4. P(r) Analysis (GNOM)

最大尺寸 Dmax dmax	88.9 Å
Rg (实空间) rg_real	27.36 Å
Rg 误差 (实空间) rg_real_error	0.50 Å
I(0) (实空间) i0_real	9.2050e+07
I(0) 误差 (实空间) i0_real_error	1.2860e+06
Rg (倒空间) rg_reciprocal	27.38 Å
I(0) (倒空间) i0_reciprocal	92050000.0000
解质量估计 total_estimate	0.8893
解质量评级 solution_quality	GOOD a GOOD solution
P(r) 峰数 n_peaks	1
主峰位置 r_peak_primary	32.2 Å
偏度 Skewness skewness	0.319
峰度 Kurtosis kurtosis	-0.303
角度范围 angular_range	— – 0.2900 Å⁻¹
当前正则化参数 α current_alpha	0.0000
最高正则化参数 α highest_alpha	24290000.0000
实空间数据点数 n_real_points	59
GNOM 版本 gnom_version	4.1.3
质量判据 quality_criteria	AN1: 0.000; Oscil: 0.863; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.998; Smooth: 0.969

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5. 晶体学与实验 5. Crystallography & Experiment

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6. 实体与聚合物信息 Entities & Polymers (10)

实体 1 Entity 1 polymer

描述 description	Cytochrome c oxidase subunit 1
分子量 formula_weight	63540.1 kDa
EC 编号 ec_number	1.9.3.1
来源方法 src_method	man
拷贝数 entity_count	1

聚合物 Polymer

聚合物类型 type	polypeptide(L)
链编号 strand_id	A
原子数 atom_count	6575

MHHHHHHHAVRASEISRVYEAYPEKKATLYFLVLGFLALIVGSLFGPFQALNYGNVDAYPLLKRLLPFVQSYYQGLTLHGVLNAIVFTQLFAQAIMVYLPARELNMRPNMGLMWLSWWMAFIGLVVAALPLLANEATVLYTFYPPLKGHWAFYLGASVFVLSTWVSIYIVLDLWRRWKAANPGKVTPLVTYMAVVFWLMWFLASLGLVLEAVLFLLPWSFGLVEGVDPLVARTLFWWTGHPIVYFWLLPAYAIIYTILPKQAGGKLVSDPMARLAFLLFLLLSTPVGFHHQFADPGIDPTWKMIHSVLTLFVAVPSLMTAFTVAASLEFAGRLRGGRGLFGWIRALPWDNPAFVAPVLGLLGFIPGGAGGIVNASFTLDYVVHNTAWVPGHFHLQVASLVTLTAMGSLYWLLPNLTGKPISDAQRRLGLAVVWLWFLGMMIMAVGLHWAGLLNVPRRAYIAQVPDAYPHAAVPMVFNVLAGIVLLVALLLFIYGLFSVLLSRERKPELAEAPLPFAEVISGPEDRRLVLAMDRIGFWFAVAAILVVLAYGPTLVQLFGHLNPVPGWRLW

来源 Source

来源生物 organism	Thermus thermophilus
NCBI 分类编号 ncbi_taxonomy_id	274
宿主生物 host_organism	Thermus thermophilus HB8

实体 2 Entity 2 polymer

描述 description	Cytochrome c oxidase subunit 2
分子量 formula_weight	18581.3 kDa
EC 编号 ec_number	1.9.3.1
来源方法 src_method	man
拷贝数 entity_count	1

聚合物 Polymer

聚合物类型 type	polypeptide(L)
链编号 strand_id	B

MVDEHKAHKAILAYEKGWLAFSLAMLFVFIALIAYTLATHTAGVIPAGKLERVDPTTVRQEGPWADPAQAVVQTGPNQYTVYVLAFAFGYQPNPIEVPQGAEIVFKITSPDVIHGFHVEGTNINVEVLPGEVSTVRYTFKRPGEYRIICNQYCGLGHQNMFGTIVVKE

来源 Source

来源生物 organism	Thermus thermophilus
NCBI 分类编号 ncbi_taxonomy_id	274
宿主生物 host_organism	Thermus thermophilus HB8

实体 3 Entity 3 polymer

描述 description	Cytochrome c oxidase polypeptide IIA
分子量 formula_weight	3769.6 kDa
来源方法 src_method	man
拷贝数 entity_count	1

聚合物 Polymer

聚合物类型 type	polypeptide(L)
链编号 strand_id	C

MEEKPKGALAVILVLTLTILVFWLGVYAVFFARG

来源 Source

来源生物 organism	Thermus thermophilus
NCBI 分类编号 ncbi_taxonomy_id	274
宿主生物 host_organism	Thermus thermophilus HB8

实体 4 Entity 4 non-polymer

描述 description	COPPER (II) ION
分子量 formula_weight	63.5 kDa
来源方法 src_method	syn
拷贝数 entity_count	1

实体 5 Entity 5 non-polymer

描述 description	PROTOPORPHYRIN IX CONTAINING FE
分子量 formula_weight	616.5 kDa
来源方法 src_method	syn
拷贝数 entity_count	1

实体 6 Entity 6 non-polymer

描述 description	HEME-AS
分子量 formula_weight	921.0 kDa
来源方法 src_method	syn
拷贝数 entity_count	1

实体 7 Entity 7 non-polymer

描述 description	(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
分子量 formula_weight	356.5 kDa
来源方法 src_method	syn
拷贝数 entity_count	15

实体 8 Entity 8 non-polymer

描述 description	CARBON MONOXIDE
分子量 formula_weight	28.0 kDa
来源方法 src_method	syn
拷贝数 entity_count	1

实体 9 Entity 9 non-polymer

描述 description	DINUCLEAR COPPER ION
分子量 formula_weight	127.1 kDa
来源方法 src_method	syn
拷贝数 entity_count	1

实体 10 Entity 10 water

描述 description	water
分子量 formula_weight	18.0 kDa
来源方法 src_method	nat
拷贝数 entity_count	182

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7. 折叠分类 (SCOP + CATH) 1 domains

CATH v4.4 (1 domains)

结构域编号 domain_id	8ajzA01
类 Class class	1 — Mainly Alpha
架构 Architecture architecture	20 — Up-down Bundle
拓扑 Topology topology	210 — Cytochrome C Oxidase; Chain A
同源超家族 H-superfamily homologous superfamily	10 — Cytochrome c oxidase-like, subunit I domain

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8. 引用文献 (1)

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晶胞边长 a length_a	145.850 Å
晶胞边长 b length_b	100.320 Å
晶胞边长 c length_c	96.620 Å
晶胞夹角 α angle_alpha	90.00 °
晶胞夹角 β angle_beta	126.76 °
晶胞夹角 γ angle_gamma	90.00 °
晶胞分子数 Z z_pdb	4

空间群 space_group	C 1 2 1
空间群编号 int_tables_number	5
晶系 crystal_system	monoclinic

分辨率 resolution	2.000 Å
最低分辨率 resolution_low	38.700 Å
R 因子 r_factor	—
R_work r_work	0.1900
R_free r_free	0.2100

fit	/app/data/saxs_computation/aj/8ajz/8ajz.fit
pddf	/app/data/pr_computation/aj/8ajz/8ajz.pr.out
profile	/app/data/saxs_computation/aj/8ajz/8ajz.dat

Serial femtosecond crystallography structure of CO bound ba3- type cytochrome c oxidase at 2 milliseconds after irradiation by a 532 nm laser

1. 蛋白身份与相关结构 Protein Identity & Related Structures

Cytochrome c oxidase subunit 1

当前结构中的状态

数据库中的同蛋白其他状态

Cytochrome c oxidase subunit 2

当前结构中的状态

数据库中的同蛋白其他状态

Cytochrome c oxidase polypeptide IIA

当前结构中的状态

数据库中的同蛋白其他状态

SAXS 散射曲线 SAXS Profile

P(r) 距离分布 P(r) Distribution

2. 结构基本信息 2. Structure Basics

3. SAXS 参数 (CRYSOL 理论计算) 3. SAXS Parameters (CRYSOL)

4. P(r) 距离分布 (GNOM 反演) 4. P(r) Analysis (GNOM)

5. 晶体学与实验 5. Crystallography & Experiment

晶胞参数 Unit Cell

对称性 Symmetry

精修参数 Refinement

衍射实验 Diffraction

6. 实体与聚合物信息 Entities & Polymers (10)

实体 1 Entity 1 polymer

聚合物 Polymer

来源 Source

实体 2 Entity 2 polymer

聚合物 Polymer

来源 Source

实体 3 Entity 3 polymer

聚合物 Polymer

来源 Source

实体 4 Entity 4 non-polymer

实体 5 Entity 5 non-polymer

实体 6 Entity 6 non-polymer

实体 7 Entity 7 non-polymer

实体 8 Entity 8 non-polymer

实体 9 Entity 9 non-polymer

实体 10 Entity 10 water

7. 折叠分类 (SCOP + CATH) 1 domains

CATH v4.4 (1 domains)

8. 引用文献 (1)

9. 文件与曲线 (10)

Files (7)

Curves (3)