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8gtn

Cryo-EM structure of the gasdermin B pore

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Isoform 4 of Gasdermin-B

Homo sapiens

UniProt Q8TAX9

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 27 No other associated polymer Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers
8et1 8et2 8gtn

3 assemblies

Heteromeric or nucleic-acid complex
5tib 5tib 5tj2 5tj2 5tj2 5tj2 5tj4 5tj4 5tj4 5tj4 5tj4 5tj4

21 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name GSDMB_HUMAN
Isoform Q8TAX9-6
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 5–241； UniProt 1–237 Author chain AA； PDBConstruct 5–241； UniProt 1–237 Author chain B； PDBConstruct 5–241； UniProt 1–237 Author chain BA； PDBConstruct 5–241； UniProt 1–237 Author chain C； PDBConstruct 5–241； UniProt 1–237 Author chain D； PDBConstruct 5–241； UniProt 1–237 Author chain E； PDBConstruct 5–241； UniProt 1–237 Author chain F； PDBConstruct 5–241； UniProt 1–237 Author chain G； PDBConstruct 5–241； UniProt 1–237 Author chain H； PDBConstruct 5–241； UniProt 1–237 Author chain I； PDBConstruct 5–241； UniProt 1–237 Author chain J； PDBConstruct 5–241； UniProt 1–237 Author chain K； PDBConstruct 5–241； UniProt 1–237 Author chain L； PDBConstruct 5–241； UniProt 1–237 Author chain M； PDBConstruct 5–241； UniProt 1–237 Author chain N； PDBConstruct 5–241； UniProt 1–237 Author chain O； PDBConstruct 5–241； UniProt 1–237 Author chain P； PDBConstruct 5–241； UniProt 1–237 Author chain Q； PDBConstruct 5–241； UniProt 1–237 Author chain R； PDBConstruct 5–241； UniProt 1–237 Author chain S； PDBConstruct 5–241； UniProt 1–237 Author chain T； PDBConstruct 5–241； UniProt 1–237 Author chain V； PDBConstruct 5–241； UniProt 1–237 Author chain W； PDBConstruct 5–241； UniProt 1–237 Author chain X； PDBConstruct 5–241； UniProt 1–237 Author chain Y； PDBConstruct 5–241； UniProt 1–237 Author chain Z； PDBConstruct 5–241； UniProt 1–237

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id8gtn
Deposition date deposition_date2022-09-08
Structure title titleCryo-EM structure of the gasdermin B pore
Keywords keywordsPyroptosis, Pore-forming, IMMUNE SYSTEM; IMMUNE SYSTEM
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

8gtn__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

8gtn__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

8gtn__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）0.00 Å
Rg (electron density)107.60 Å
Total Rg107.50 Å
Atom count48276
Residues5832
Excluded volume867030 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 8gtn__assembly_1__model_1 27-meric （27） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (1)

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7. Citations (1)