Cytochrome c oxidase subunit 1
Thermus thermophilus
State in the Current Structure
| Assembly | Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Associated Components | Method and Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|
| 1 | Protein heterocomplex Heteromer Protein × 3 PDB declaration: trimeric（3） Consistent with protein copy count | Chain A； UniProt 2–562 | Not recorded | Cytochrome c oxidase subunit 2 × 1 （Q5SJ80） Cytochrome c oxidase polypeptide 2A × 1 （P82543） CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CUA DINUCLEAR COPPER ION × 1 | X-RAY DIFFRACTION X-ray crystallization conditions：LIPIDIC CUBIC PHASE；pH 5.3；298 K；1.4 M NaCl, 100 mM MES pH 5.3 with 36 % to 39 % (v/v) PEG 400 | Resolution 2.12 Å R-free 0.184 |
Other States of the Same Protein in the Database
Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.
| Other PDB | Difference from Current Entry 8HUA | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Method and Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 1EHK CRYSTAL STRUCTURE OF THE ABERRANT BA3-CYTOCHROME-C OXIDASE FROM THERMUS THERMOPHILUS Deposited 2000-02-21 | Different construct Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain A
1–562（562 aa）
Fragment：SUBUNIT I
|
Not recorded | BNG nonyl beta-D-glucopyranoside × 3 CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CUA DINUCLEAR COPPER ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7；293 K；PEG 2000, Bis-Tris buffer, nonyl-beta-D-glucoside, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 293K
|
Resolution 2.40 Å R-free 0.264 |
| 2QPD An unexpected outcome of surface-engineering an integral membrane protein: Improved crystallization of cytochrome ba3 oxidase from Thermus thermophilus Deposited 2007-07-23 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain A
2–562（561 aa）
|
Mutation：K258R | CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CUA DINUCLEAR COPPER ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7；291 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris pH 7.0, 6.5 mM n-nonyl-beta-D-glucopyranoside, VAPOR DIFFUSION, SITTING DROP, temperature 291K
|
Resolution 3.25 Å R-free 0.307 |
| 2QPE An unexpected outcome of surface-engineering an integral membrane protein: Improved crystallization of cytochrome ba3 oxidase from Thermus thermophilus Deposited 2007-07-23 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain A
2–562（561 aa）
|
Mutation：K258R | CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CUA DINUCLEAR COPPER ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7；291 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris, pH 7.0, 6.5 mM n-nonyl-beta-D-glucopyranoside, VAPOR DIFFUSION, SITTING DROP, temperature 291K
|
Resolution 2.90 Å R-free 0.302 |
| 3BVD Structure of Surface-engineered Cytochrome ba3 Oxidase from Thermus thermophilus under Xenon Pressure, 100psi 5min Deposited 2008-01-07 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain A
2–562（561 aa）
|
Mutation：K258R | CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 7 CUA DINUCLEAR COPPER ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION；pH 7；297 K；6-9% PEG 2000, 50mM KCl, 7.5-30mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside , VAPOR DIFFUSION, temperature 297K
|
Resolution 3.37 Å R-free 0.336 |
| 3EH3 Structure of the reduced form of cytochrome ba3 oxidase from Thermus thermophilus Deposited 2008-09-11 | Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain A
2–562（561 aa）
Fragment：UNP residues 6-562
|
Mutation：K258R | CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CUA DINUCLEAR COPPER ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；Peg 2000, Bis-tris, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 297K
|
Resolution 3.10 Å R-free 0.300 |
| 3EH3 Structure of the reduced form of cytochrome ba3 oxidase from Thermus thermophilus Deposited 2008-09-11 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–562（561 aa）
Fragment：UNP residues 6-562
|
Mutation：K258R | CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；Peg 2000, Bis-tris, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 297K
|
Resolution 3.10 Å R-free 0.300 |
| 3EH4 Structure of the reduced form of cytochrome ba3 oxidase from Thermus thermophilus Deposited 2008-09-11 | Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain A
2–562（561 aa）
Fragment：UNP residues 2-562
|
Mutation：K258R | CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CUA DINUCLEAR COPPER ION × 1 BNG nonyl beta-D-glucopyranoside × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；Peg 2000, Bis-tris, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 297K
|
Resolution 2.90 Å R-free 0.268 |
| 3EH4 Structure of the reduced form of cytochrome ba3 oxidase from Thermus thermophilus Deposited 2008-09-11 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–562（561 aa）
Fragment：UNP residues 2-562
|
Mutation：K258R | CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；Peg 2000, Bis-tris, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 297K
|
Resolution 2.90 Å R-free 0.268 |
| 3EH5 Structure of the reduced form of cytochrome ba3 oxidase from Thermus thermophilus Deposited 2008-09-11 | Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain A
2–562（561 aa）
Fragment：UNP residues 2-562
|
Mutation：K258R | CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 BNG nonyl beta-D-glucopyranoside × 4 CUA DINUCLEAR COPPER ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；Peg 2000, Bis-tris, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 297K
|
Resolution 2.80 Å R-free 0.257 |
| 3EH5 Structure of the reduced form of cytochrome ba3 oxidase from Thermus thermophilus Deposited 2008-09-11 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–562（561 aa）
Fragment：UNP residues 2-562
|
Mutation：K258R | CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 BNG nonyl beta-D-glucopyranoside × 3 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；Peg 2000, Bis-tris, pH 7.0, VAPOR DIFFUSION, SITTING DROP, temperature 297K
|
Resolution 2.80 Å R-free 0.257 |
| 3QJQ The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus Deposited 2011-01-30 | Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain A
2–562（561 aa）
|
Not recorded | CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris pH 7.0, 6.5 mM n-nonyl-beta-D glucopyranoside, VAPOR DIFFUSION, SITTING DROP, temperature 297K
|
Resolution 2.90 Å R-free 0.284 |
| 3QJR The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus Deposited 2011-01-30 | Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain A
2–562（561 aa）
|
Not recorded | CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris pH 7.0, 6.5 mM n-nonyl-beta-D-glucopyranoside
, VAPOR DIFFUSION, SITTING DROP, temperature 297K
|
Resolution 3.20 Å R-free 0.367 |
| 3QJS The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus Deposited 2011-01-30 | Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain A
2–562（561 aa）
|
Not recorded | CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris pH 7.0, 6.5 mM n-nonyl-beta-D-glucopyranoside , VAPOR DIFFUSION, SITTING DROP, temperature 297K
|
Resolution 2.80 Å R-free 0.265 |
| 3QJT The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus Deposited 2011-01-30 | Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain A
2–562（561 aa）
|
Not recorded | CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris pH 7.0, 6.5 mM n-nonyl-beta-D-glucopyranoside , VAPOR DIFFUSION, SITTING DROP, temperature 297K
|
Resolution 2.95 Å R-free 0.323 |
| 3QJU The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus Deposited 2011-01-30 | Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain A
2–562（561 aa）
|
Not recorded | CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris pH 7.0, 6.5 mM n-nonyl-beta-D-glucopyranoside, VAPOR DIFFUSION, SITTING DROP, temperature 297K
|
Resolution 2.90 Å R-free 0.329 |
| 3QJV The structure of and photolytic induced changes of carbon monoxide binding to the cytochrome ba3-oxidase from Thermus thermophilus Deposited 2011-01-30 | Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain A
2–562（561 aa）
|
Not recorded | CU1 COPPER (I) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 7；297 K；7% PEK 2K, 50 mM KCl, 20 mM Bis-Tris pH 7.0, 6.5 mM n-nonyl-beta-D-glucopyranoside, VAPOR DIFFUSION, SITTING DROP, temperature 297K
|
Resolution 2.80 Å R-free 0.274 |
| 3S33 Structure of Thermus thermophilus cytochrome ba3 oxidase 10s after Xe depressurization Deposited 2011-05-17 | Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain A
2–562（561 aa）
|
Not recorded | CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 5 CUA DINUCLEAR COPPER ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7；297 K；12-17% PEG 2000, 0-200mM KCl, 15-60mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside, vapor diffusion, hanging drop, temperature 297K
|
Resolution 4.45 Å R-free 0.350 |
| 3S38 Structure of Thermus thermophilus cytochrome ba3 oxidase 30s after Xe depressurization Deposited 2011-05-17 | Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain A
2–562（561 aa）
|
Not recorded | CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 4 CUA DINUCLEAR COPPER ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7；297 K；12-17% PEG 2000, 0-200mM KCl, 15-60mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside, vapor diffusion, hanging drop, temperature 297K
|
Resolution 4.20 Å R-free 0.325 |
| 3S39 Structure of Thermus thermophilus cytochrome ba3 oxidase 60s after Xe depressurization Deposited 2011-05-17 | Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain A
2–562（561 aa）
|
Not recorded | CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 4 CUA DINUCLEAR COPPER ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7；297 K；12-17% PEG 2000, 0-200mM KCl, 15-60mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside, vapor diffusion, hanging drop, temperature 297K
|
Resolution 4.80 Å R-free 0.341 |
| 3S3A Structure of Thermus thermophilus cytochrome ba3 oxidase 120s after Xe depressurization Deposited 2011-05-18 | Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain A
2–562（561 aa）
|
Not recorded | CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 4 CUA DINUCLEAR COPPER ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7；297 K；12-17% PEG 2000, 0-200mM KCl, 15-60mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside, vapor diffusion, hanging drop, temperature 297K
|
Resolution 4.25 Å R-free 0.330 |
| 3S3B Structure of Thermus thermophilus cytochrome ba3 oxidase 240s after Xe depressurization Deposited 2011-05-18 | Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain A
2–562（561 aa）
|
Not recorded | CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 3 CUA DINUCLEAR COPPER ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 7；297 K；12-17% PEG 2000, 0-200mM KCl, 15-60mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside, vapor diffusion, hanging drop, temperature 297K
|
Resolution 3.30 Å R-free 0.299 |
| 3S3C Structure of Thermus thermophilus cytochrome ba3 oxidase 360s after Xe depressurization Deposited 2011-05-18 | Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain A
2–562（561 aa）
|
Not recorded | CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 3 CUA DINUCLEAR COPPER ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 7；297 K；12-17% PEG 2000, 0-200mM KCl, 15-60mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside, vapor diffusion, hanging drop, temperature 297K
|
Resolution 4.00 Å R-free 0.373 |
| 3S3D Structure of Thermus thermophilus cytochrome ba3 oxidase 480s after Xe depressurization Deposited 2011-05-18 | Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain A
2–562（561 aa）
|
Not recorded | CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 XE XENON × 3 CUA DINUCLEAR COPPER ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 7；297 K；12-17% PEG 2000, 0-200mM KCl, 15-60mM bis-Tris pH 7.0, 6.5mM nonyl-B-D-glucopyranoside, vapor diffusion, hanging drop, temperature 297K
|
Resolution 3.75 Å R-free 0.293 |
| 3S8F 1.8 A structure of ba3 cytochrome c oxidase from Thermus thermophilus in lipid environment Deposited 2011-05-27 | Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain A
2–562（561 aa）
|
Not recorded | CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
LIPIDIC CUBIC PHASE；pH 6；293 K；40-45% PEG 400, 1.0-1.6M NaCl, 100mM sodium cacodylate trihydrate pH 5.5-6.5, lipidic cubic phase with monolein, temperature 293K
|
Resolution 1.80 Å R-free 0.215 |
| 3S8G 1.8 A structure of ba3 cytochrome c oxidase mutant (A120F) from Thermus thermophilus in lipid environment Deposited 2011-05-27 | Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain A
2–562（561 aa）
|
Not recorded | HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CU COPPER (II) ION × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 20 CUA DINUCLEAR COPPER ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
LIPIDIC CUBIC PHASE；293 K；40-45% PEG 400, 1.0-1.6M NaCl, 100mM sodium cacodylate trihydrate pH 5.5-6.5, lipidic cubic phase with monolein, temperature 293K
|
Resolution 1.80 Å R-free 0.196 |
| 4FA7 Structure of Recombinant Cytochrome ba3 Oxidase mutant A204F from Thermus thermophilus Deposited 2012-05-21 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain A
2–562（561 aa）
|
Mutation：A204F | CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PEO HYDROGEN PEROXIDE × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate, 1.6M NaCl, 40% PEG400, pH 6.5, Lipidic Cubic Phase, temperature 293K
|
Resolution 2.50 Å R-free 0.220 |
| 4FAA Structure of Recombinant Cytochrome ba3 Oxidase mutant A120F+A204F from Thermus thermophilus Deposited 2012-05-21 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain A
2–562（561 aa）
|
Mutation：Y120F,204F | CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PEO HYDROGEN PEROXIDE × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate, 1.6M NaCl, 40% PEG400, pH 6.5, Lipidic Cubic Phase, temperature 293K
|
Resolution 2.80 Å R-free 0.254 |
| 4G70 Structure of Recombinant Cytochrome ba3 Oxidase mutant V236T from Thermus thermophilus Deposited 2012-07-19 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain A
2–562（561 aa）
|
Mutation：A120F, V236T | HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 CU COPPER (II) ION × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate PH 6.5, 1.6M NaCl, 40% PEG400
, Lipidic Cubic Phase, temperature 293K
|
Resolution 2.60 Å R-free 0.252 |
| 4G71 Structure of Recombinant Cytochrome ba3 Oxidase mutant V236N from Thermus thermophilus Deposited 2012-07-19 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain A
2–562（561 aa）
|
Mutation：A120F, V236N | CUB CU(I)-S-MO(IV)(=O)O-NBIC CLUSTER × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate PH 6.5, 1.6M NaCl, 40% PEG400
, Lipidic Cubic Phase, temperature 293K
|
Resolution 2.90 Å R-free 0.224 |
| 4G72 Structure of Recombinant Cytochrome ba3 Oxidase mutant V236M from Thermus thermophilus Deposited 2012-07-19 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain A
2–562（561 aa）
|
Mutation：A120F, V236M | CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate PH 6.5, 1.6M NaCl, 40% PEG400
, Lipidic Cubic Phase, temperature 293K
|
Resolution 3.19 Å R-free 0.223 |
| 4G7Q Structure of Recombinant Cytochrome ba3 Oxidase mutant V236L from Thermus thermophilus Deposited 2012-07-20 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain A
2–562（561 aa）
|
Mutation：A120F, V236L | CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate PH 6.5, 1.6M NaCl, 40% PEG400
, Lipidic Cubic Phase, temperature 293K
|
Resolution 2.60 Å R-free 0.232 |
| 4G7R Structure of Recombinant Cytochrome ba3 Oxidase mutant V236A from Thermus thermophilus Deposited 2012-07-20 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain A
2–562（561 aa）
|
Mutation：A120F, V236A | CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CUA DINUCLEAR COPPER ION × 1 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 3.05 Å R-free 0.231 |
| 4G7S Structure of Recombinant Cytochrome ba3 Oxidase mutant V236I from Thermus thermophilus Deposited 2012-07-20 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain A
2–562（561 aa）
|
Mutation：A120F, V236I | CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CUA DINUCLEAR COPPER ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate PH 6.5, 1.6M NaCl, 40% PEG400
, Lipidic Cubic Phase, temperature 293K
|
Resolution 2.00 Å R-free 0.207 |
| 4GP4 Structure of Recombinant Cytochrome ba3 Oxidase mutant Y133F from Thermus thermophilus Deposited 2012-08-20 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain A
2–562（561 aa）
|
Mutation：Y133F | CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate, 1.6M NaCl, 40% PEG400, pH 6.5, Lipidic Cubic Phase, temperature 293K
|
Resolution 2.80 Å R-free 0.227 |
| 4GP5 Structure of Recombinant Cytochrome ba3 Oxidase mutant Y133W from Thermus thermophilus Deposited 2012-08-20 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain A
2–562（561 aa）
|
Mutation：Y133W | CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate, 1.6M NaCl, 40% PEG400, pH 6.5, Lipidic Cubic Phase, temperature 293K
|
Resolution 2.70 Å R-free 0.230 |
| 4GP8 Structure of Recombinant Cytochrome ba3 Oxidase mutant Y133W+T231F from Thermus thermophilus Deposited 2012-08-20 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain A
2–562（561 aa）
|
Mutation：Y133W, T231F | CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PER PEROXIDE ION × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
LIPIDIC CUBIC PHASE；pH 6.5；293 K；50mM Sodium Cacodylate, 1.6M NaCl, 40% PEG400, pH 6.5, Lipidic Cubic Phase, temperature 293K
|
Resolution 2.80 Å R-free 0.227 |
| 4N4Y Structure of Recombinant Cytochrome ba3 Oxidase mutant G232V from Thermus thermophilus Deposited 2013-10-08 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain A
2–562（561 aa）
|
Mutation：G232V | CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 PEO HYDROGEN PEROXIDE × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 16 CUA DINUCLEAR COPPER ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
LIPIDIC CUBIC PHASE；pH 6.5；293 K；50 mM sodium cacodylate, pH 6.5, 1.6 M sodium chloride, 40% PEG400, LIPIDIC CUBIC PHASE, temperature 293K
|
Resolution 2.90 Å R-free 0.225 |
| 5NDC Structure of ba3-type cytochrome c oxidase from Thermus thermophilus by serial femtosecond crystallography Deposited 2017-03-08 | Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain A
2–562（561 aa）
|
Not recorded | CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CUA DINUCLEAR COPPER ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
LIPIDIC CUBIC PHASE；pH 5.3；293 K；100mM sodium cacodylate trihydrate pH 5.3, 37% PEG400, 1.4M NaCl
Room temperature for 2-3 days
|
Resolution 2.30 Å R-free 0.197 |
| 8AJZ Serial femtosecond crystallography structure of CO bound ba3- type cytochrome c oxidase at 2 milliseconds after irradiation by a 532 nm laser Deposited 2022-07-29 | Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain A
2–562（561 aa）
|
Not recorded | CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
LIPIDIC CUBIC PHASE；pH 5.3；298 K；100 mM 2-Morpholinoethanesulfonic acid, 34-38 % PEG 400 (v/v), 1.4 M NaCl, pH 5.3
|
Resolution 2.00 Å R-free 0.210 |
| 8K65 Serial femtosecond crystallography structure of CO bound ba3- type cytochrome c oxidase without pump laser irradiation Deposited 2023-07-25 | Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain A
2–562（561 aa）
|
Not recorded | CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
LIPIDIC CUBIC PHASE；pH 5.3；293 K；34-38 % PEG 400 (v/v), 1.4 M NaCl, pH 5.3
|
Resolution 2.00 Å R-free 0.196 |
| 8K6Y Serial femtosecond crystallography structure of photo dissociated CO from ba3- type cytochrome c oxidase determined by extrapolation method Deposited 2023-07-25 | Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain A
2–562（561 aa）
|
Not recorded | CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CMO CARBON MONOXIDE × 1 CUA DINUCLEAR COPPER ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
LIPIDIC CUBIC PHASE；pH 5.3；293 K；34-38 % PEG 400 (v/v), 1.4 M NaCl, pH 5.3
|
Resolution 2.00 Å R-free 0.435 |
| 9GDF Chloride bound structure of oxidized ba3-type cytochrome c oxidase confirmed by single-wavelength anomalous diffraction Deposited 2024-08-05 | Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain A
2–562（561 aa）
|
Not recorded | CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CL CHLORIDE ION × 2 CUA DINUCLEAR COPPER ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
LIPIDIC CUBIC PHASE；pH 5.3；298 K；1.4 M NaCl, 100 mM MES. 40-43 % (v/v) PEG 400
|
Resolution 2.28 Å R-free 0.197 |
| 9VDJ Serial synchrotron crystallography structure of a ba3-type cytochrome c oxidase using a goniometer-compatible chip-based platform Deposited 2025-06-08 | Different experimental conditions Different structure-quality metrics | Assembly 1 Protein heterocomplex Heteromer；Protein × 3 PDB declaration: trimeric |
Chain A
2–562（561 aa）
|
Not recorded | CU COPPER (II) ION × 1 HEM PROTOPORPHYRIN IX CONTAINING FE × 1 HAS HEME-AS × 1 OLC (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate × 15 CUA DINUCLEAR COPPER ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
LIPIDIC CUBIC PHASE；293 K；0.1M MES (pH 5.3), 1.4M NaCl, 39-41% PEG 400
|
Resolution 2.30 Å R-free 0.264 |
40 other PDB entries and 43 assemblies. Open the comparison page and filter oligomeric states
View Construct and Data Evidence
| UniProt name | COX1_THET8 |
| Isoform | — |
| PDB entities | 1 |
| Chains and sequence ranges | Author chain A； PDBConstruct 9–569； UniProt 2–562 |
