Homo sapiens
| Assembly | 物理组成 | 蛋白状态 | 分子拷贝数 | 共同组分 | 数据核对 |
|---|---|---|---|---|---|
| 1 | 蛋白–DNA | 单体 | 蛋白 1 DNA 2 | ;DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3') ; × 1 ;DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3') ; × 1 SULFATE ION × 1 SODIUM ION × 2 water × 3 | 与全部聚合物一致 |
| UniProt名称 | DPOB_HUMAN |
| Isoform | — |
| PDB实体 | 3 |
| 链与序列区间 | 作者链 A； PDB构建体 2–335； UniProt 1–334 |
页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。
| 条目编号 entry_id | 8icm |
| 沉积日期 deposition_date | 1996-01-04 |
| 结构标题 title | DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DATP (1 MILLIMOLAR), MNCL2 (5 MILLIMOLAR), AND AMMONIUM SULFATE (75 MILLIMOLAR) |
| 关键词 keywords | ;DNA-DIRECTED DNA POLYMERASE, DNA REPLICATION, DNA REPAIR, NUCLEOTIDYLTRANSFERASE, COMPLEX (NUCLEOTIDYLTRANSFERASE-DNA, TRANSFERASE-DNA complex ;; TRANSFERASE/DNA |
| 实验方法 method | X-RAY DIFFRACTION |
页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 23.76 Å |
| Rg（电子密度） | 23.35 Å |
| 总 Rg | 24.14 Å |
| 原子数 | 2919 |
| 残基数 | 342 |
| 排除体积 | 51137 ų |
| 最大 q | 0.500 Å⁻¹ |
| 结构域编号 domain_id | d8icma1 |
| 类 Class class | a — All alpha proteins |
| 折叠类型 Fold fold | a.60 — SAM domain-like |
| 超家族 Superfamily superfamily | a.60.6 — DNA polymerase beta, N-terminal domain-like |
| 家族 Family family | a.60.6.1 — DNA polymerase beta, N-terminal domain-like |
| 结构域编号 domain_id | d8icma3 |
| 类 Class class | a — All alpha proteins |
| 折叠类型 Fold fold | a.60 — SAM domain-like |
| 超家族 Superfamily superfamily | a.60.12 — PsbU/PolX domain-like |
| 家族 Family family | a.60.12.1 — DNA polymerase beta-like, second domain |
| 结构域编号 domain_id | d8icma4 |
| 类 Class class | d — Alpha and beta proteins (a+b) |
| 折叠类型 Fold fold | d.218 — Nucleotidyltransferase |
| 超家族 Superfamily superfamily | d.218.1 — Nucleotidyltransferase |
| 家族 Family family | d.218.1.2 — DNA polymerase beta-like |
| 结构域编号 domain_id | 8icmA01 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 150 — DNA polymerase; domain 1 |
| 同源超家族 H-superfamily homologous superfamily | 110 — DNA polymerase beta, N-terminal domain-like |
| 结构域编号 domain_id | 8icmA02 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 150 — DNA polymerase; domain 1 |
| 同源超家族 H-superfamily homologous superfamily | 20 — 5' to 3' exonuclease, C-terminal subdomain |
| 结构域编号 domain_id | 8icmA03 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 460 — Beta Polymerase; domain 2 |
| 同源超家族 H-superfamily homologous superfamily | 10 — Beta Polymerase, domain 2 |
| 结构域编号 domain_id | 8icmA04 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 210 — Beta Polymerase; domain 3 |
| 同源超家族 H-superfamily homologous superfamily | 10 — DNA polymerase, thumb domain |