8jp4

Cryo-EM structure of the head region of full-length ERGIC-53 with MCFD2 (form A)

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Protein ERGIC-53

Homo sapiens

UniProt P49257

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 8 Multiple coagulation factor deficiency protein 2 × 4 (Q8NI22) CALCIUM ION × 16 ZINC ION × 4 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name LMAN1_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 1–510; UniProt 1–510 Author chain B; PDBConstruct 1–510; UniProt 1–510 Author chain E; PDBConstruct 1–510; UniProt 1–510 Author chain F; PDBConstruct 1–510; UniProt 1–510

Multiple coagulation factor deficiency protein 2

Homo sapiens

UniProt Q8NI22

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 8 Protein ERGIC-53 × 4 (P49257) CALCIUM ION × 16 ZINC ION × 4 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name MCFD2_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain C; PDBConstruct 5–124; UniProt 27–146 Author chain D; PDBConstruct 5–124; UniProt 27–146 Author chain G; PDBConstruct 5–124; UniProt 27–146 Author chain H; PDBConstruct 5–124; UniProt 27–146

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id8jp4
Deposition date deposition_date2023-06-10
Structure title titleCryo-EM structure of the head region of full-length ERGIC-53 with MCFD2 (form A)
Keywords keywordscargo receptor, calcium, zinc, PROTEIN TRANSPORT; PROTEIN TRANSPORT
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

8jp4__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

8jp4__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

8jp4__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)41.45 Å
Rg (electron density)40.91 Å
Total Rg41.30 Å
Atom count13500
Residues1678
Excluded volume236840 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 8jp4__assembly_1__model_1 octameric (8) Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (4)

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7. Citations (1)