8qmz

Soluble epoxide hydrolase in complex with RK4

Method: X-RAY DIFFRACTION
▼

1. Protein Identity and Related Structures Protein Identity & Related Structures

Bifunctional epoxide hydrolase 2

Homo sapiens

UniProt P34913

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein monomer Monomer Protein 1 ;(3~{a}~{R},6~{a}~{S})-~{N}-[(2,4-dichlorophenyl)methyl]-2-(4-methylphenyl)sulfonyl-3,3~{a},4,5,6,6~{a}-hexahydro-1~{H}-cyclopenta[c]pyrrole-5-carboxamide ; × 1 1,2-ETHANEDIOL × 4 water × 1 Consistent with protein count
2 Protein monomer Monomer Protein 1 ;(3~{a}~{R},6~{a}~{S})-~{N}-[(2,4-dichlorophenyl)methyl]-2-(4-methylphenyl)sulfonyl-3,3~{a},4,5,6,6~{a}-hexahydro-1~{H}-cyclopenta[c]pyrrole-5-carboxamide ; × 1 1,2-ETHANEDIOL × 5 water × 1 Consistent with protein count
3 Protein monomer Monomer Protein 1 ;(3~{a}~{R},6~{a}~{S})-~{N}-[(2,4-dichlorophenyl)methyl]-2-(4-methylphenyl)sulfonyl-3,3~{a},4,5,6,6~{a}-hexahydro-1~{H}-cyclopenta[c]pyrrole-5-carboxamide ; × 1 1,2-ETHANEDIOL × 2 water × 1 Consistent with protein count
4 Protein monomer Monomer Protein 1 ;(3~{a}~{R},6~{a}~{S})-~{N}-[(2,4-dichlorophenyl)methyl]-2-(4-methylphenyl)sulfonyl-3,3~{a},4,5,6,6~{a}-hexahydro-1~{H}-cyclopenta[c]pyrrole-5-carboxamide ; × 1 1,2-ETHANEDIOL × 5 water × 1 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name HYES_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 25–358; UniProt 222–555 Author chain B; PDBConstruct 25–358; UniProt 222–555 Author chain C; PDBConstruct 25–358; UniProt 222–555 Author chain D; PDBConstruct 25–358; UniProt 222–555

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

▼

2. Structure Basics 2. Structure Basics

Entry ID entry_id8qmz
Deposition date deposition_date2023-09-25
Last revision last_revision2024-02-14
Structure title titleSoluble epoxide hydrolase in complex with RK4
Keywords keywordsCOMPLEX, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, HYDROLASE; HYDROLASE
Experimental Method methodX-RAY DIFFRACTION
▼

3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

8qmz__assembly_2__model_1

Assembly 2 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

8qmz__assembly_2__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

8qmz__assembly_2__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)19.44 Å
Rg (electron density)18.22 Å
Total Rg19.17 Å
Atom count2596
Residues318
Excluded volume46422 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 8qmz__assembly_1__model_1 monomeric (1) Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 8qmz__assembly_2__model_1 monomeric (1) Success 4.1.3-1-20251215 (887e7ef) View Download
3 1 8qmz__assembly_3__model_1 monomeric (1) Success 4.1.3-1-20251215 (887e7ef) View Download
4 1 8qmz__assembly_4__model_1 monomeric (1) Success 4.1.3-1-20251215 (887e7ef) View Download
▶

4. Crystallography and Experiment 4. Crystallography & Experiment

▶

5. Entities and Polymers Entities & Polymers (4)

▶

7. Citations (1)