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8smk

hPAD4 bound to Activating Fab hA362

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Protein-arginine deiminase type-4

Homo sapiens

UniProt Q9UM07

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 6 Activating Fab 362 heavy chain × 2 Activating Fab 362 light chain × 2 CALCIUM ION × 8 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
9dop 9dpz

2 assemblies

Homodimer
1wd8 1wd9 1wda 2dw5 3apm 3apn 3b1t 3b1u 4x8c 4x8g 5n0m 5n0y

17 assemblies; showing the first 12

Homotetramer
9huj

1 assemblies

Other homooligomers

None

Heteromeric or nucleic-acid complex
2dew 2dex 2dey 4dkt 8r8u 8r8v 8smk 8sml

8 assemblies

View Construct and Data Evidence
UniProt name PADI4_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 34–695； UniProt 2–663 Author chain D； PDBConstruct 34–695； UniProt 2–663

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id8smk
Deposition date deposition_date2023-04-26
Structure title titlehPAD4 bound to Activating Fab hA362
Keywords keywordscomplex, enzyme, inflammation, calcium binding, IMMUNE SYSTEM; IMMUNE SYSTEM
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

8smk__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

8smk__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

8smk__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）51.91 Å
Rg (electron density)51.89 Å
Total Rg51.96 Å
Atom count15298
Residues1982
Excluded volume273150 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 8smk__assembly_1__model_1 hexameric （6） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (4)

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7. Citations (1)