← Back to search
8t9b

Structure of the CK variant of Fab F1 (FabC-F1) in complex with the C-terminal FN3 domain of EphA2

Method: X-RAY DIFFRACTION
▼

1. Protein Identity and Related Structures Protein Identity & Related Structures

Ephrin type-A receptor 2

Homo sapiens

UniProt P29317

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 3 CK variant of Fab F1 heavy chain × 1 CK variant of Fab F1 light chain × 1 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 3 CK variant of Fab F1 heavy chain × 1 CK variant of Fab F1 light chain × 1 Consistent with protein count
3 Protein heterocomplex Heteromer Protein 3 CK variant of Fab F1 heavy chain × 1 CK variant of Fab F1 light chain × 1 Consistent with protein count
4 Protein heterocomplex Heteromer Protein 3 CK variant of Fab F1 heavy chain × 1 CK variant of Fab F1 light chain × 1 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1mqb 1mqb 2e8n 2x10 3hpn 3hpn 3hpn 3hpn 3hpn 3hpn 3kka 3kka

89 assemblies; showing the first 12

Homodimer
2k9y 3c8x 3hpn 3hpn 3hpn 4pdo 5ek7

7 assemblies

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
2kso 2x11 3czu 3hei 3hei 3hei 3hei 3hei 3hei 3hei 3hei 3mbw

46 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name EPHA2_HUMAN
Isoform —
PDB entities 3
Chains and sequence ranges Author chain I； PDBConstruct 1–94； UniProt 436–529 Author chain J； PDBConstruct 1–94； UniProt 436–529 Author chain K； PDBConstruct 1–94； UniProt 436–529 Author chain L； PDBConstruct 1–94； UniProt 436–529

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

▼

2. Structure Basics 2. Structure Basics

Entry ID entry_id8t9b
Deposition date deposition_date2023-06-23
Structure title titleStructure of the CK variant of Fab F1 (FabC-F1) in complex with the C-terminal FN3 domain of EphA2
Keywords keywordsenhanced crystallization, EphA2 binding, expressed protein, Fab, Complex, receptor clustering, IMMUNE SYSTEM; IMMUNE SYSTEM
Experimental Method methodX-RAY DIFFRACTION
▼

3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

8t9b__assembly_2__model_1

Assembly 2 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

8t9b__assembly_2__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

8t9b__assembly_2__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）28.53 Å
Rg (electron density)28.22 Å
Total Rg28.79 Å
Atom count3966
Residues532
Excluded volume69679 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 8t9b__assembly_1__model_1 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 8t9b__assembly_2__model_1 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
3 1 8t9b__assembly_3__model_1 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
4 1 8t9b__assembly_4__model_1 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
▶

4. Crystallography and Experiment 4. Crystallography & Experiment

▶

5. Entities and Polymers Entities & Polymers (3)

▶

7. Citations (3)