SAXSdb — 8w8m

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1. Protein Identity and Related Structures Protein Identity & Related Structures

Myeloid differentiation primary response protein MyD88

Homo sapiens

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein homooligomer	Homooligomer	Protein 102	No other associated polymer	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	MYD88_HUMAN
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain 1A； PDBConstruct 1–144； UniProt 153–296 Author chain 1B； PDBConstruct 1–144； UniProt 153–296 Author chain 1C； PDBConstruct 1–144； UniProt 153–296 Author chain 1D； PDBConstruct 1–144； UniProt 153–296 Author chain 1E； PDBConstruct 1–144； UniProt 153–296 Author chain 1F； PDBConstruct 1–144； UniProt 153–296 Author chain 2A； PDBConstruct 1–144； UniProt 153–296 Author chain 2B； PDBConstruct 1–144； UniProt 153–296 Author chain 2C； PDBConstruct 1–144； UniProt 153–296 Author chain 2D； PDBConstruct 1–144； UniProt 153–296 Author chain 2E； PDBConstruct 1–144； UniProt 153–296 Author chain 2F； PDBConstruct 1–144； UniProt 153–296 Author chain 3A； PDBConstruct 1–144； UniProt 153–296 Author chain 3B； PDBConstruct 1–144； UniProt 153–296 Author chain 3C； PDBConstruct 1–144； UniProt 153–296 Author chain 3D； PDBConstruct 1–144； UniProt 153–296 Author chain 3E； PDBConstruct 1–144； UniProt 153–296 Author chain 3F； PDBConstruct 1–144； UniProt 153–296 Author chain A1； PDBConstruct 1–144； UniProt 153–296 Author chain A2； PDBConstruct 1–144； UniProt 153–296 Author chain A3； PDBConstruct 1–144； UniProt 153–296 Author chain B1； PDBConstruct 1–144； UniProt 153–296 Author chain B2； PDBConstruct 1–144； UniProt 153–296 Author chain B3； PDBConstruct 1–144； UniProt 153–296 Author chain C1； PDBConstruct 1–144； UniProt 153–296 Author chain C2； PDBConstruct 1–144； UniProt 153–296 Author chain C3； PDBConstruct 1–144； UniProt 153–296 Author chain D1； PDBConstruct 1–144； UniProt 153–296 Author chain D2； PDBConstruct 1–144； UniProt 153–296 Author chain D3； PDBConstruct 1–144； UniProt 153–296 Author chain E1； PDBConstruct 1–144； UniProt 153–296 Author chain E2； PDBConstruct 1–144； UniProt 153–296 Author chain E3； PDBConstruct 1–144； UniProt 153–296 Author chain F1； PDBConstruct 1–144； UniProt 153–296 Author chain F2； PDBConstruct 1–144； UniProt 153–296 Author chain F3； PDBConstruct 1–144； UniProt 153–296 Author chain G1； PDBConstruct 1–144； UniProt 153–296 Author chain G2； PDBConstruct 1–144； UniProt 153–296 Author chain G3； PDBConstruct 1–144； UniProt 153–296 Author chain H1； PDBConstruct 1–144； UniProt 153–296 Author chain H2； PDBConstruct 1–144； UniProt 153–296 Author chain H3； PDBConstruct 1–144； UniProt 153–296 Author chain I1； PDBConstruct 1–144； UniProt 153–296 Author chain I2； PDBConstruct 1–144； UniProt 153–296 Author chain I3； PDBConstruct 1–144； UniProt 153–296 Author chain J1； PDBConstruct 1–144； UniProt 153–296 Author chain J2； PDBConstruct 1–144； UniProt 153–296 Author chain J3； PDBConstruct 1–144； UniProt 153–296 Author chain K1； PDBConstruct 1–144； UniProt 153–296 Author chain K2； PDBConstruct 1–144； UniProt 153–296 Author chain K3； PDBConstruct 1–144； UniProt 153–296 Author chain L1； PDBConstruct 1–144； UniProt 153–296 Author chain L2； PDBConstruct 1–144； UniProt 153–296 Author chain L3； PDBConstruct 1–144； UniProt 153–296 Author chain M1； PDBConstruct 1–144； UniProt 153–296 Author chain M2； PDBConstruct 1–144； UniProt 153–296 Author chain M3； PDBConstruct 1–144； UniProt 153–296 Author chain N1； PDBConstruct 1–144； UniProt 153–296 Author chain N2； PDBConstruct 1–144； UniProt 153–296 Author chain N3； PDBConstruct 1–144； UniProt 153–296 Author chain O1； PDBConstruct 1–144； UniProt 153–296 Author chain O2； PDBConstruct 1–144； UniProt 153–296 Author chain O3； PDBConstruct 1–144； UniProt 153–296 Author chain P1； PDBConstruct 1–144； UniProt 153–296 Author chain P2； PDBConstruct 1–144； UniProt 153–296 Author chain P3； PDBConstruct 1–144； UniProt 153–296 Author chain Q1； PDBConstruct 1–144； UniProt 153–296 Author chain Q2； PDBConstruct 1–144； UniProt 153–296 Author chain Q3； PDBConstruct 1–144； UniProt 153–296 Author chain R1； PDBConstruct 1–144； UniProt 153–296 Author chain R2； PDBConstruct 1–144； UniProt 153–296 Author chain R3； PDBConstruct 1–144； UniProt 153–296 Author chain S1； PDBConstruct 1–144； UniProt 153–296 Author chain S2； PDBConstruct 1–144； UniProt 153–296 Author chain S3； PDBConstruct 1–144； UniProt 153–296 Author chain T1； PDBConstruct 1–144； UniProt 153–296 Author chain T2； PDBConstruct 1–144； UniProt 153–296 Author chain T3； PDBConstruct 1–144； UniProt 153–296 Author chain U1； PDBConstruct 1–144； UniProt 153–296 Author chain U2； PDBConstruct 1–144； UniProt 153–296 Author chain U3； PDBConstruct 1–144； UniProt 153–296 Author chain V1； PDBConstruct 1–144； UniProt 153–296 Author chain V2； PDBConstruct 1–144； UniProt 153–296 Author chain V3； PDBConstruct 1–144； UniProt 153–296 Author chain W1； PDBConstruct 1–144； UniProt 153–296 Author chain W2； PDBConstruct 1–144； UniProt 153–296 Author chain W3； PDBConstruct 1–144； UniProt 153–296 Author chain X1； PDBConstruct 1–144； UniProt 153–296 Author chain X2； PDBConstruct 1–144； UniProt 153–296 Author chain X3； PDBConstruct 1–144； UniProt 153–296 Author chain Y1； PDBConstruct 1–144； UniProt 153–296 Author chain Y2； PDBConstruct 1–144； UniProt 153–296 Author chain Y3； PDBConstruct 1–144； UniProt 153–296 Author chain YD； PDBConstruct 1–144； UniProt 153–296 Author chain YE； PDBConstruct 1–144； UniProt 153–296 Author chain YF； PDBConstruct 1–144； UniProt 153–296 Author chain Z1； PDBConstruct 1–144； UniProt 153–296 Author chain Z2； PDBConstruct 1–144； UniProt 153–296 Author chain Z3； PDBConstruct 1–144； UniProt 153–296 Author chain ZD； PDBConstruct 1–144； UniProt 153–296 Author chain ZE； PDBConstruct 1–144； UniProt 153–296 Author chain ZF； PDBConstruct 1–144； UniProt 153–296

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	8w8m
Deposition date deposition_date	2023-09-04
Structure title title	Cryo-EM structure of helical filament of MyD88 TIR
Keywords keywords	signaling protein, innate immunity, IMMUNE SYSTEM; IMMUNE SYSTEM
Experimental Method method	ELECTRON MICROSCOPY

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

8w8m__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

8w8m__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

8w8m__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	0.00 Å
Rg (electron density)	168.50 Å
Total Rg	168.50 Å
Atom count	113934
Residues	13770
Excluded volume	2059000 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`8w8m__assembly_1__model_1`	102-meric （102）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (1)

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Unit-cell length a length_a	1.000 Å
Unit-cell length b length_b	1.000 Å
Unit-cell length c length_c	1.000 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	—

Space group space_group	P 1
Space-group number int_tables_number	1
Crystal system crystal_system	triclinic

Resolution resolution	3.28 Å
Resolution测定Method resolution_method	—
颗粒数 num_particles	14934

Description description	Myeloid differentiation primary response protein MyD88
Molecular weight formula_weight	16841.8 kDa
Source method src_method	man
Copy count entity_count	102

Polymer type type	polypeptide(L)
Chain IDs strand_id	;D2,D3,E1,E2,E3,F1,F2,F3,D1,A2,A3,B1,B2,B3,C1,C2,C3,A1,J2,J3,K1,K2,K3,L1,L2,L3,J1,G2,G3,H1,H2,H3,I1,I2,I3,G1,M2,M3,N1,N2,N3,O1,O2,O3,M1,P2,P3,Q1,Q2,Q3,R1,R2,R3,P1,S2,S3,T1,T2,T3,U1,U2,U3,S1,V2,V3,W1,W2,W3,X1,X2,X3,V1,Y2,Y3,Z1,Z2,Z3,1A,2A,3A,Y1,2B,3B,1C,2C,3C,1D,2D,3D,1B,ZD,YE,ZE,1E,YF,ZF,1F,YD,2E,3E,2F,3F ;
Atom count atom_count	113934

Cryo-EM structure of helical filament of MyD88 TIR

1. Protein Identity and Related Structures Protein Identity & Related Structures

Myeloid differentiation primary response protein MyD88

State in the Current Structure

Other States of the Same Protein in the Database

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

8w8m__assembly_1__model_1

8w8m__assembly_1__model_1 | I(q)

8w8m__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

冷冻电镜 EM 3D

5. Entities and Polymers Entities & Polymers (1)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

7. Citations (2)

Source organism organism	Homo sapiens
Common name common_name	human
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	Escherichia coli

Cryo-EM structure of helical filament of MyD88 TIR

1. Protein Identity and Related Structures Protein Identity & Related Structures

Myeloid differentiation primary response protein MyD88

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

8w8m__assembly_1__model_1

8w8m__assembly_1__model_1 | I(q)

8w8m__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

冷冻电镜 EM 3D

5. Entities and Polymers Entities & Polymers (1)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

7. Citations (2)