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8wsw

The Crystal Structure of LIMK2a from Biortus

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

LIM domain kinase 2

Homo sapiens

UniProt P53671

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein monomer Monomer Protein 1 ~{N}-[5-[2-[2,6-bis(chloranyl)phenyl]-5-[bis(fluoranyl)methyl]pyrazol-3-yl]-1,3-thiazol-2-yl]-2-methyl-propanamide × 1 1,2-ETHANEDIOL × 7 water × 1 Consistent with protein count
2 Protein monomer Monomer Protein 1 ~{N}-[5-[2-[2,6-bis(chloranyl)phenyl]-5-[bis(fluoranyl)methyl]pyrazol-3-yl]-1,3-thiazol-2-yl]-2-methyl-propanamide × 1 1,2-ETHANEDIOL × 4 water × 1 Consistent with protein count
3 Protein monomer Monomer Protein 1 ~{N}-[5-[2-[2,6-bis(chloranyl)phenyl]-5-[bis(fluoranyl)methyl]pyrazol-3-yl]-1,3-thiazol-2-yl]-2-methyl-propanamide × 1 1,2-ETHANEDIOL × 4 water × 1 Consistent with protein count
4 Protein monomer Monomer Protein 1 ~{N}-[5-[2-[2,6-bis(chloranyl)phenyl]-5-[bis(fluoranyl)methyl]pyrazol-3-yl]-1,3-thiazol-2-yl]-2-methyl-propanamide × 1 1,2-ETHANEDIOL × 3 water × 1 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1x6a 5nxd 5nxd 7qhg 7qhg 8gi4 8gi4 8gi4 8gi4 8gi4 8gi4 8gi4

17 assemblies; showing the first 12

Homodimer
4tpt 8s3x 8s3x

3 assemblies

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex

None

View Construct and Data Evidence
UniProt name LIMK2_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–303； UniProt 330–632 Author chain B； PDBConstruct 1–303； UniProt 330–632 Author chain C； PDBConstruct 1–303； UniProt 330–632 Author chain D； PDBConstruct 1–303； UniProt 330–632

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id8wsw
Deposition date deposition_date2023-10-17
Last revision last_revision2023-11-15
Structure title titleThe Crystal Structure of LIMK2a from Biortus
Keywords keywordsKinase, Serine/threonine-protein kinase, Transferase, ATP-binding, Metal-binding, Nucleotide-binding, Zinc; TRANSFERASE
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

8wsw__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

8wsw__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

8wsw__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）20.20 Å
Rg (electron density)19.35 Å
Total Rg20.39 Å
Atom count2292
Residues281
Excluded volume41559 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 8wsw__assembly_1__model_1 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 8wsw__assembly_2__model_1 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
3 1 8wsw__assembly_3__model_1 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
4 1 8wsw__assembly_4__model_1 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (4)

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7. Citations (1)