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9o3r

Crystal Structure of I64A Variant of D-Dopachrome Tautomerase (D-DT)

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

D-dopachrome decarboxylase

Homo sapiens

UniProt P30046

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 3 CALCIUM ION × 2 water × 3 Consistent with protein count
2 Protein homooligomer Homooligomer Protein 3 CALCIUM ION × 1 water × 3 Consistent with protein count
3 Protein homooligomer Homooligomer Protein 3 CALCIUM ION × 5 water × 3 Consistent with protein count
4 Protein homooligomer Homooligomer Protein 3 CALCIUM ION × 2 water × 3 Consistent with protein count
5 Protein homooligomer Homooligomer Protein 3 CALCIUM ION × 1 water × 3 Consistent with protein count
6 Protein homooligomer Homooligomer Protein 3 CALCIUM ION × 1 water × 3 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1dpt 1dpt 1dpt

3 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers
4q3f 4q3f 4q3f 6c5f 6c5f 6c5f 7mru 7mrv 7mse 7mse 7mse 7mw7

52 assemblies; showing the first 12

Heteromeric or nucleic-acid complex

None

View Construct and Data Evidence
UniProt name DOPD_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain AAA； PDBConstruct 1–117； UniProt 2–118 Author chain BBB； PDBConstruct 1–117； UniProt 2–118 Author chain CCC； PDBConstruct 1–117； UniProt 2–118 Author chain DDD； PDBConstruct 1–117； UniProt 2–118 Author chain EEE； PDBConstruct 1–117； UniProt 2–118 Author chain FFF； PDBConstruct 1–117； UniProt 2–118 Author chain GGG； PDBConstruct 1–117； UniProt 2–118 Author chain HHH； PDBConstruct 1–117； UniProt 2–118 Author chain III； PDBConstruct 1–117； UniProt 2–118 Author chain JJJ； PDBConstruct 1–117； UniProt 2–118 Author chain KKK； PDBConstruct 1–117； UniProt 2–118 Author chain LLL； PDBConstruct 1–117； UniProt 2–118 Author chain MMM； PDBConstruct 1–117； UniProt 2–118 Author chain NNN； PDBConstruct 1–117； UniProt 2–118 Author chain OOO； PDBConstruct 1–117； UniProt 2–118 Author chain PPP； PDBConstruct 1–117； UniProt 2–118 Author chain QQQ； PDBConstruct 1–117； UniProt 2–118 Author chain RRR； PDBConstruct 1–117； UniProt 2–118

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id9o3r
Deposition date deposition_date2025-04-07
Last revision last_revision2026-05-06
Structure title titleCrystal Structure of I64A Variant of D-Dopachrome Tautomerase (D-DT)
Keywords keywordsDDT mutant, DDT, enzymatic activity, keto-to-enol tautomerization, tautomerization, CYTOKINE; CYTOKINE
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

9o3r__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

9o3r__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

9o3r__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）19.99 Å
Rg (electron density)18.84 Å
Total Rg19.77 Å
Atom count2590
Residues348
Excluded volume46459 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 9o3r__assembly_1__model_1 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 9o3r__assembly_2__model_1 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
3 1 9o3r__assembly_3__model_1 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
4 1 9o3r__assembly_4__model_1 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
5 1 9o3r__assembly_5__model_1 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
6 1 9o3r__assembly_6__model_1 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

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7. Citations (1)