Cryo-EM structure of stabilized H5N1 A/Texas/37/2024 hemagglutinin fused to foldon

Method: ELECTRON MICROSCOPY D_max: 132.8 Å Quality: REASONABLE

SAXS Profile

P(r) Distribution

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1. Structure Basics

entry_id	9pr3
deposition_date	2025-07-23
title	Cryo-EM structure of stabilized H5N1 A/Texas/37/2024 hemagglutinin fused to foldon
keywords	HPAI H5N1, Influenza Hemagglutinin, stabilization, VIRAL PROTEIN; VIRAL PROTEIN
method	ELECTRON MICROSCOPY

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Download Data

SAXS curve (.dat) P(r) distribution (.pr.out) Structure (CIF)

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2. SAXS Parameters (CRYSOL)

rg_guinier	40.19 Å
rg_electron	39.46 Å
i0	428172000.00
molecular_weight	165140.0 kDa
excluded_volume	204960 Å³
envelope_volume	272820 Å³
shell_volume	57806 Å³
envelope_diameter	131.1 Å
shell_rg	44.70 Å
envelope_rg	39.25 Å
shape_rg	39.50 Å
total_rg	39.63 Å
total_atoms	22776
n_residues	1404
n_harmonics	20
q_range	— – 0.5000 Å⁻¹
n_points	101
shell_type	directional
solvent_density	0.3340 e/Å³
contrast_shell	0.0300 e/Å³
crysol_version	4.1.3

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3. P(r) Analysis (GNOM)

dmax	132.8 Å
rg_real	40.22 Å
rg_real_error	0.99 Å
i0_real	4.2820e+08
i0_real_error	7.7310e+06
rg_reciprocal	40.19 Å
i0_reciprocal	428200000.0000
total_estimate	0.5805
solution_quality	REASONABLE a REASONABLE solution
n_peaks	1
r_peak_primary	44.2 Å
skewness	0.392
kurtosis	-0.385
angular_range	— – 0.1950 Å⁻¹
current_alpha	0.0000
highest_alpha	37190000.0000
n_real_points	40
gnom_version	4.1.3
quality_criteria	AN1: 0.000; Oscil: 0.825; Stabil: 1.000; Sysdev: 0.025; Positv: 1.000; Valcen: 0.994; Smooth: 0.000

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4. Crystallography & Experiment

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5. Entities & Polymer Info (2)

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6. Citations (1)

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length_a	1.000 Å
length_b	1.000 Å
length_c	1.000 Å
angle_alpha	90.00 °
angle_beta	90.00 °
angle_gamma	90.00 °
z_pdb	—

space_group	P 1
int_tables_number	1
crystal_system	—

resolution	3.20 Å
resolution_method	—
num_particles	54035

description	Hemagglutinin, foldon fusion
formula_weight	63096.8 kDa
src_method	man
entity_count	3

type	polypeptide(L)
strand_id	A,B,C
atom_count	22776

Cryo-EM structure of stabilized H5N1 A/Texas/37/2024 hemagglutinin fused to foldon

SAXS Profile

P(r) Distribution

1. Structure Basics

Download Data

2. SAXS Parameters (CRYSOL)

3. P(r) Analysis (GNOM)

4. Crystallography & Experiment

Unit Cell

Symmetry

EM 3D

5. Entities & Polymer Info (2)

Entity 1 polymer

Polymer

Source

Entity 2 non-polymer

6. Citations (1)

7. Files & Curves (10)

Files (7)

Curves (3)

organism	Influenza A virus
ncbi_taxonomy_id	11320
host_organism	Homo sapiens

description	2-acetamido-2-deoxy-beta-D-glucopyranose
formula_weight	221.2 kDa
src_method	syn
entity_count	15

fit	/app/data/saxs_computation/pr/9pr3/9pr3.fit
pddf	/app/data/pr_computation/pr/9pr3/9pr3.pr.out
profile	/app/data/saxs_computation/pr/9pr3/9pr3.dat