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9pzr

GluN1/GluN2A in complex with polyclonal autoantibody Fab fragments (class 2), glycine- and glutamate-bound state

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Glutamate receptor ionotropic, NMDA 1

Rattus norvegicus

UniProt P35439

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 8 Glutamate receptor ionotropic, NMDA 2A × 2 （Q00959） Polyclonal antibody Fab fragment, termed FabEnc1 × 4 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1pb7 1pb8 1pb9 1pbq 1pbq 1y1m 1y1m 1y1z 1y20 4kfq 4kfq 6ove

12 assemblies

Homodimer
1y1m 3q41 3q41 4kcc

4 assemblies

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
2a5t 4nf4 4nf5 4nf6 4nf8 4pe5 5dex 5fxg 5fxh 5fxi 5fxj 5fxk

105 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name NMDZ1_RAT
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–847； UniProt 1–847 Author chain C； PDBConstruct 1–847； UniProt 1–847

Glutamate receptor ionotropic, NMDA 2A

Rattus norvegicus

UniProt Q00959

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 8 Glutamate receptor ionotropic, NMDA 1 × 2 （P35439） Polyclonal antibody Fab fragment, termed FabEnc1 × 4 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
2a5s 6ove

2 assemblies

Homodimer
2a5s

1 assemblies

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
2a5t 4nf4 4nf5 4nf6 4nf8 5dex 5i56 5i57 5i58 5i59 5jty 5tpw

59 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name NMDE1_RAT
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B； PDBConstruct 1–866； UniProt 1–866 Author chain D； PDBConstruct 1–866； UniProt 1–866

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id9pzr
Deposition date deposition_date2025-08-11
Structure title titleGluN1/GluN2A in complex with polyclonal autoantibody Fab fragments (class 2), glycine- and glutamate-bound state
Keywords keywordsligand-gated ion channel, NMDA, antibody, complex, TRANSPORT PROTEIN; TRANSPORT PROTEIN
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

9pzr__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

9pzr__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

9pzr__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）56.41 Å
Rg (electron density)55.16 Å
Total Rg54.83 Å
Atom count23598
Residues3362
Excluded volume413970 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 9pzr__assembly_1__model_1 octameric （8） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

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7. Citations (1)