9q1n
Crystal structure of human TEAD2-Yap binding domain covalently bound to an allosteric regulator
SAXS Profile
P(r) Distribution
1. Structure Basics
| entry_id | 9q1n |
| deposition_date | 2025-08-14 |
| title | Crystal structure of human TEAD2-Yap binding domain covalently bound to an allosteric regulator |
| keywords | ;TEAD, inhibitor, complex, covalent, allosteric, Transcriptional enhancer factor TEF-4, TRANSCRIPTION, TRANSCRIPTION-INHIBITOR complex ;; TRANSCRIPTION/INHIBITOR |
| method | X-RAY DIFFRACTION |
Download Data
2. SAXS Parameters (CRYSOL)
| rg_guinier | 23.24 Å |
| rg_electron | 22.31 Å |
| i0 | 71067400.00 |
| molecular_weight | 44478.0 kDa |
| excluded_volume | 43268 ų |
| envelope_volume | 71439 ų |
| shell_volume | 26295 ų |
| envelope_diameter | 75.8 Å |
| shell_rg | 29.52 Å |
| envelope_rg | 22.50 Å |
| shape_rg | 22.30 Å |
| total_rg | 22.99 Å |
| total_atoms | 3376 |
| n_residues | 405 |
| n_harmonics | 20 |
| q_range | — – 0.5000 Å−1 |
| n_points | 101 |
| shell_type | directional |
| solvent_density | 0.3340 e/ų |
| contrast_shell | 0.0300 e/ų |
| crysol_version | 4.1.3 |
3. P(r) Analysis (GNOM)
| dmax | 72.6 Å |
| rg_real | 23.12 Å |
| rg_real_error | 0.37 Å |
| i0_real | 7.1070e+07 |
| i0_real_error | 8.3740e+05 |
| rg_reciprocal | 23.15 Å |
| i0_reciprocal | 71070000.0000 |
| total_estimate | 0.9038 |
| solution_quality | EXCELLENT a EXCELLENT solution |
| n_peaks | 2 |
| r_peak_primary | 29.1 Å |
| skewness | 0.197 |
| kurtosis | -0.461 |
| angular_range | — – 0.3400 Å−1 |
| current_alpha | 0.0000 |
| highest_alpha | 10790000.0000 |
| n_real_points | 66 |
| gnom_version | 4.1.3 |
| quality_criteria | AN1: 0.000; Oscil: 0.922; Stabil: 1.000; Sysdev: 1.000; Positv: 1.000; Valcen: 0.995; Smooth: 0.984 |